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MARIO ALLEGRA

Pubblicazioni

Data Titolo Tipologia Scheda
2024 Golden tomato juice enhances hepatic PPAR-α expression, mitigates metabolic dysfunctions and influences redox balance in a high-fat diet rat model Articolo in rivista Vai
2024 Unraveling the “metabolic syndrome and cognitive decline” detrimental loop: What role for Mediterranean phytonutrients? Contributo in atti di convegno pubblicato in volume Vai
2024 Indicaxanthin prevents eryptosis induced by cigarette smoke extract by interfering with active Fas-mediated signaling Articolo in rivista Vai
2024 The remarkable impact of Opuntia Ficus Indica fruit administration on metabolic syndrome: Correlations between cognitive functions, oxidative stress and lipid dysmetabolism in the high-fat, diet-fed rat model Articolo in rivista Vai
2024 Positive impact of indicaxanthin from Opuntia ficusindica fruit on high-fat diet–induced neuronal damage and gut microbiota dysbiosis Articolo in rivista Vai
2023 A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation Articolo in rivista Vai
2023 Oncogenic BRAF and p53 Interplay in Melanoma Cells and the Effects of the HDAC Inhibitor ITF2357 (Givinostat) Articolo in rivista Vai
2023 A Mixture of Dietary Plant Sterols at Nutritional Relevant Serum Concentration Inhibits Extrinsic Pathway of Eryptosis Induced by Cigarette Smoke Extract Articolo in rivista Vai
2023 Multicomponent Antibiofilm Lipid Nanoparticles as Novel Platform to Ameliorate Resveratrol Properties: Preliminary Outcomes on Fibroblast Proliferation and Migration Articolo in rivista Vai
2023 Anti-Inflammatory Effects of Nutritionally Relevant Concentrations of Oleuropein and Hydroxytyrosol on Peripheral Blood Mononuclear Cells: An Age-Related Analysis Articolo in rivista Vai
2023 Long-Term Ingestion of Sicilian Black Bee Chestnut Honey and/or D-Limonene Counteracts Brain Damage Induced by High Fat-Diet in Obese Mice Articolo in rivista Vai
2023 “Golden” Tomato Consumption Ameliorates Metabolic Syndrome: A Focus on the Redox Balance in the High-Fat-Diet-Fed Rat Articolo in rivista Vai
2023 A Deadly Liaison between Oxidative Injury and p53 Drives Methyl-Gallate-Induced Autophagy and Apoptosis in HCT116 Colon Cancer Cells Articolo in rivista Vai
2022 Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging Review essay (rassegna critica) Vai
2022 Redox Properties, Bioactivity and Health Effects of Indicaxanthin, a Bioavailable Phytochemical from Opuntia ficus indica, L.: A Critical Review of Accumulated Evidence and Perspectives Review essay (rassegna critica) Vai
2022 Cigarette Smoke Extract Induces p38 MAPK-Initiated, Fas-Mediated Eryptosis Articolo in rivista Vai
2022 Modulation of Human Motor Cortical Excitability and Plasticity by Opuntia Ficus Indica Fruit Consumption: Evidence from a Preliminary Study through Non-Invasive Brain Stimulation Articolo in rivista Vai
2022 Green Extraction of Polyphenols from Waste Bentonite to Produce Functional Antioxidant Excipients for Cosmetic and Pharmaceutical Purposes: A Waste-to-Market Approach Articolo in rivista Vai
2022 Anti-Eryptotic Activity of Food-Derived Phytochemicals and Natural Compounds Articolo in rivista Vai
2022 In Silico Design, Synthesis and Biological Evaluation of Anticancer Arylsulfonamide Endowed with Anti-Telomerase Activity Articolo in rivista Vai
2022 Indicaxanthin from Opuntia ficus-indica fruit ameliorates glucose dysmetabolism and counteracts insulin resistance in high-fat-diet-fed mice Articolo in rivista Vai
2021 Inhibitory effects of cynaropicrin on human melanoma progression by targeting MAPK, NF-κB, and Nrf-2 signaling pathways in vitro Articolo in rivista Vai
2021 Suicidal erythrocyte death in metabolic syndrome Articolo in rivista Vai
2021 Redox systems, oxidative stress, and antioxidant defences in health and disease Nota o commento Vai
2021 Amyloid‐beta induces different expression pattern of tissue transglutaminase and its isoforms on olfactory ensheathing cells: Modulatory effect of indicaxanthin Articolo in rivista Vai
2021 Composizione comprendente indicaxantina per uso per la prevenzione e il trattamento del diabete mellito di tipo 2, obesità, stress ossidativo e patologie infiammatorie. Brevetto Vai
2021 Evaluation of the IKKβ Binding of Indicaxanthin by Induced-Fit Docking, Binding Pose Metadynamics, and Molecular Dynamics Articolo in rivista Vai
2021 Redox regulation of metabolic syndrome: From biochemical mechanisms to nutritional interventions Nota o commento Vai
2021 EFFECTS OF INDICAXANTHIN ON HUMAN MOTOR CORTICAL EXCITABILITY AND PLASTICITY Abstract in atti di convegno pubblicato in rivista Vai
2020 Proeryptotic activity of 4-hydroxynonenal: A new potential physiopathological role for lipid peroxidation products Articolo in rivista Vai
2020 Anti-Proliferative Activity of A Hydrophilic Extract of Manna from Fraxinus angustifolia Vahl through Mitochondrial Pathway-Mediated Apoptosis and Cell Cycle Arrest in Human Colon Cancer Cells Articolo in rivista Vai
2020 The phytochemical indicaxanthin synergistically enhances cisplatin-induced apoptosis in hela cells via oxidative stress-dependent p53/p21waf1 axis Articolo in rivista Vai
2019 Antioxidant and anti-inflammatory properties of plants extract Nota o commento Vai
2019 7-Keto-Cholesterol and Cholestan-3beta, 5alpha, 6beta-Triol Induce Eryptosis through Distinct Pathways Leading to NADPH Oxidase and Nitric Oxide Synthase Activation Articolo in rivista Vai
2019 Phenolic composition of hydrophilic extract of manna from sicilian Fraxinus angustifolia vahl and its reducing, antioxidant and anti-inflammatory activity in vitro Articolo in rivista Vai
2019 Indicaxanthin from Opuntia ficus indica (L. Mill) Inhibits Oxidized LDL-Mediated Human Endothelial Cell Dysfunction through Inhibition of NF- κB Activation Articolo in rivista Vai
2019 Increased eryptosis in smokers is associated with the antioxidant status and C-reactive protein levels Articolo in rivista Vai
2019 Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes Articolo in rivista Vai
2019 Indicaxanthin, a multi-target natural compound from Opuntia ficus-indica fruit: From its poly-pharmacological effects to biochemical mechanisms and molecular modelling studies Articolo in rivista Vai
2018 Brain Distribution and Modulation of Neuronal Excitability by Indicaxanthin From Opuntia Ficus Indica Administered at Nutritionally-Relevant Amounts Articolo in rivista Vai
2018 Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression Articolo in rivista Vai
2018 Hyaluronic acid and α-elastin based hydrogel for three dimensional culture of vascular endothelial cells Articolo in rivista Vai
2018 Short-term cactus pear [opuntia ficus-indica (L.) Mill] fruit supplementation ameliorates the inflammatory profile and is associated with improved antioxidant status among healthy humans Articolo in rivista Vai
2016 Monofloral honeys by Sicilian black honeybee (Apis mellifera ssp. sicula) have high reducing power and antioxidant capacity Articolo in rivista Vai
2015 Indicaxanthin from Opuntia ficus-indica Crosses the Blood−Brain Barrier and Modulates Neuronal Bioelectric Activity in Rat Hippocampus at Dietary-Consistent Amounts. Articolo in rivista Vai
2015 IL-1b induces DNA demethylation, at genome level and in specific CpG sites of IL-6 and IL-8 genes in human intestinal epithelial cells Abstract in rivista Vai
2015 Valutazione degli effetti antiossidanti del Resolvis OmegaTM in un modello di disfunzione corneale in vitro. Abstract in rivista Vai
2015 Cactus pear fruit extract exerts anti-inflammatory effects in carrageenin-induced rat pleurisy Articolo in rivista Vai
2015 Dietary indicaxanthin from cactus pear (Opuntia ficus-indica L. Mill) fruit prevents eryptosis induced by oxysterols in a hypercholesterolaemia relevant proportion and adhesion of human erythrocytes to endothelial cell layers Articolo in rivista Vai
2014 Oxysterol mixture in hypercholesterolemia-relevant proportion causes oxidative stress-dependent eryptotic activity. Proceedings Vai
2014 In vitro digestion of beta glucan enriched pasta: polysaccharide molecular characterization and antioxidant activity of bioaccessible fraction. Proceedings Vai
2014 Indicaxanthin from Opuntia Ficus Indica exerts antioxidant and anti-inflammatory effects in an in vitro model of human corneal dysfunction. Proceedings Vai
2014 Pro-oxidant activity of indicaxanthin from Opuntia ficus indica modulates arachidonate metabolism and prostaglandin synthesis through lipid peroxide production in LPS-stimulated RAW 264.7 macrophages. Articolo in rivista Vai
2014 Hyaluronic acid, elastin and heparin containing scaffolds for the treatment of skin chronic wounds Proceedings Vai
2014 Indicaxanthin from cactus pear fruit exerts anti-inflammatory effects in carrageenin-induced rat pleurisy Articolo in rivista Vai
2014 Reducing and antioxidant properties of aqueous extracts of manna from Fraxinus ornus (Oleaceae). Proceedings Vai
2014 Oxysterol mixture in hypercholesterolemia-relevant proportion causes oxidative stress-dependent eryptosis Articolo in rivista Vai
2014 Indicaxanthin inhibits NADPH oxidase (NOX)-1 activation and NF-κB-dependent release of inflammatory mediators and prevents the increase of epithelial permeability in IL-1β-exposed Caco-2 cells Articolo in rivista Vai
2013 Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca++ increase and oxidative stress Articolo in rivista Vai
2013 Trans-epithelial transport of the betalain pigments indicaxanthin and betanin across Caco-2 cell monolayers and influence of food matrix Articolo in rivista Vai
2013 IL-1. induces DNA demethylation at genome level and in specific CpG sites of IL-6 and IL-8 genes in human intestinal epithelial cells Abstract in atti di convegno pubblicato in volume Vai
2013 Eryptosis by major components of a plasma-compatible mixture of oxysterols. Proceedings Vai
2012 Modulation of Th1/Th17 equilibrium in vitro by Indicaxanthin from Opuntia Ficus Indica (L.Mill). Proceedings Vai
2012 The diet phytochemical Indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis via inhibition of redox unbalance, cytosolic Ca2+ increase and NF-kB activation. Proceedings Vai
2012 Polymeric proanthocyanidins from Sicilian pistachio (Pistacia vera L.) nut extract inhibit lipopolysaccharide-induced inflammatory response in RAW 264.7 cells Articolo in rivista Vai
2011 Antiinflammatory effects of pistachio nut proanthocyanidins in LPS-stimulated RAW264.7 cells Proceedings Vai
2011 Cross-talk between minimally primed HL-60 cells and resting HUVEC reveals a crucial role for adhesion over extracellularly released oxidants. Articolo in rivista Vai
2011 Phytochemical indicaxanthin prevents 7-ketocholesterol-induced oxidative stress and cell cycle arrest in murine macrophages Proceedings Vai
2010 Transepithelial transport of betalainic phytochemicals in Caco-2 cell monolayers. Proceedings Vai
2009 Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes Articolo in rivista Vai
2009 Lipoperoxyl radical scavenging activity of the phytochemical betanin and its aglycone in aqueous/lipid membrane system. Kinetics and mechanistic aspects. Proceedings Vai
2009 Indicaxanthin exerts anti-inflammatory effects on carrageenin-induced rat pleurisy. Proceedings Vai
2009 Uptake of Betanin and Indicaxanthin by Caco-2 cell monolayer. Proceedings Vai
2009 Partition of Indicaxanthin in Membrane Biomimetic Systems. A Kinetic and Modeling Approach Articolo in rivista Vai
2008 Sicilian pistachio nut extract inhibits inflammatory response in lipopolysaccharide-stimulated macrophages. Proceedings Vai
2008 Kinetics of the lipoperoxyl radical-scavenging of betanin and betanidin in solution. Proceedings Vai
2007 Betanin inhibits icam-1 expression in endothelial cells co-cultured with activated HL-60 cells Proceedings Vai
2007 Kinetics of the lipoperoxyl radical-scavenging activity of indicaxanthin in solution and unilamellar liposomes Articolo in rivista Vai
2007 Antioxidant activity of Sicilian Pistachio (Pistacia vera, L. var. Bronte) nut extracts and its bioactive components Articolo in rivista Vai
2007 Cactus Pear Fruit Extract exerts anti-inflammatory effects on carrageenan-induced rat pleurisy. Proceedings Vai
2007 Inhibition of the TCR-mediated activation of naïve murine T cells by Cactus Pear Fruit Extracts. Proceedings Vai
2007 Indicaxanthin up-regulates COX-2 gene and increases cyclopentenone levels in LPS-activated RAW264.7 macrophages. Proceedings Vai
2007 Antioxidant activity of sicilian caper (Capparis spinosa L.) and its bioactive compounds Proceedings Vai
2007 Betanin inhibits the myeloperoxidase/nitrite-induced oxidation of human low-density lipoproteins Articolo in rivista Vai
2006 Indicaxanthin and betanin suppress LPS-induced NF-kB activation and modulate the levels of inflammatory mediators iNOS, COX-2 and PGE2 in macrophages Proceedings Vai
2006 Cytoprotective effects of the antioxidant phytochemical indicaxanthin in β-thalassemia red blood cells. Articolo in rivista Vai
2005 ADHESION OF ACTIVATED HL-60 TO ENDOTHELIAL CELLS UP-REGULATES ICAM-1 EXPRESSION. Proceedings Vai
2005 Biothiols, taurine, and lipid-soluble antioxidants in the edible pulp of Sicilian cactus pear (Opuntia ficus-indica) fruits and changes of bioactive juice components upon industrial processing Articolo in rivista Vai
2005 Betanin protects endothelial cell dysfunction produced by activated HL-60 Proceedings Vai
2005 BETANIN INHIBITS MPO-NITRITE-MEDIATED PEROXIDATION OF HUMAN LOW-DENSITY LIPOPROTEINS Proceedings Vai
2005 Distribution of betalain pigments in red blood cells after consuption of cactus pear fruits and increased resistance of the cells to ex vivo induced oxidative hemolysis in humans Articolo in rivista Vai
2005 Betanin inhibits myeloperoxidase/nitrite-mediated peroxidation of human low-density lipoprotein. Proceedings Vai
2005 Mechanism of interaction of betanin and indicaxanthin with human myeloperoxidase and hypochlorous acid Articolo in rivista Vai
2004 Absorption, excretion, and distribution of dietary antioxidant betalains in LDLs: potential health effects of betalains in humans Articolo in rivista Vai
2004 Absorption and distribution in erytrocytes and low density lipoproteins of betalains from cactus pear (Opuntia ficus indica) in healthy humans. Potential health effects of the dietary betalains Proceedings Vai
2004 Absorption and distribution in erythrocytes and low density lipoproteins of betalains from cacus pear (Opuntia Ficus Indica) in healthy humans. Potential health effects of the dietary betalains Capitolo o Saggio Vai
2004 Supplementation with cactus pear (Opuntia ficus-indica) fruit decreases oxidative stress in healthy humans: A comparative study with vitamin C Articolo in rivista Vai
2004 Betanin inhibits myeloperoxidase/nitrite-mediated peroxidation of human low-density lipoprotein Proceedings Vai
2004 Betanin inhibits myeloperoxidase/nitrite-mediated peroxidation of human low-density lipoprotein. Proceedings Vai
2004 Anti-inflammatory properties of betanin from cactus pear (Opuntia Ficus Indica) in an endothelial cell model. Proceedings Vai
2004 Antioxidant Betalains from Cactus Pear (Opuntia Ficus Indica) inhibit endothelial ICAM-1 expression Articolo in rivista Vai
2003 Increased resistance to oxidation of betalain-enriched human low density lipoproteins Articolo in rivista Vai