BIRS Lectures on Applied Biotechnology 2019
Dip. Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche – STEBICEF
Aula 10 ore 15:00 Viale delle Scienze ed. 16, Palermo
Prof. Giuseppe Balistreri
Head Macromolecular Dynamics Lab
University of Helsinki
Harnessing the power of genome-wide screens and artificial intelligence: rediscovering cell
biology from omics to single molecule.
The lecture will give an introduction of different state-of-the-art genome-wide screening methodologies and
how to use machine learning (i.e. artificial intelligence) to automatically classify single cells into distinct
phenotypic classes. The follow-up phase of the screens will be the central part of the talk, which will focus on
Imaging viral infection in live cells at single-molecule resolution: One flew over the virus nest
In this lecture the principles of super-resolution microscopy will be introduced, particularly PALM and
dSTORM, and how to use these imaging techniques to study single proteins in live cells during a viral
infection. How to adapt these technologies and approaches to other biological systems to study any aspect of
cell biology will also be discussed.