Studi Osservazionali in corso
Ascolta
[#TOT Trial in corso: 31] - [ultimo aggiornamento: 17/09/2026]
| Title |
A prospective, observational cohort study to evaluate the clinical impact of novel monoclonal antibodies (MAB) in B-cell Non-Hodgkin Lymphoma (NHL) in Italian clinical practice. Studio di coorte osservazionale prospettico per valutare nei pazienti con linfoma non-Hodgkin a cellule B l’impatto clinico dei nuovi anticorpi monoclonali MAB nella pratica clinica italiana. |
| NCT number | NCT06008691 FIL-MAB |
| Conditions | Non-Hodgkin Lymphoma, B-cell |
| Interventions | Drug: "novel" MAB (alone or in combination) |
| Sponsor | Fondazione Italiana Linfomi - ETS |
| Gender | Female; Male |
| Age | 18 Years and older (Adult, Older Adult ) |
| Phases | |
| Enrollment | 1500 |
| Study Type | Observational |
| Study Designs | Observational Model : Cohort Time Perspective: Prospective |
| Start Date | 27/12/2023 |
| Completion Date | 31/10/2038 |
| Locations | Italy - A.O.U. Policlinico P. Giaccone Palermo, U.O.C. di Ematologia, Dott.ssa Salvatrice Mancuso |
| URL | https://clinicaltrials.gov/study/NCT06008691 |
| Study Title | ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing |
| NCT Number | NCT06324682 Other IDs: 825/2022/Oss/AOUFe |
| Conditions | Arrhythmias, Cardiac|Atrioventricular Block|Reduced Systolic Function|Atrial Fibrillation|Bradyarrhythmia|Ventricular Tachycardia|Ventricular Dysfunction|Ventricular Fibrillation|Ventricular Arrythmia|Atrioventricular Nodal Disease|Atrioventricular Conduction Defects|Atrioventricular Block Complete|Atrioventricular Block Incomplete|Atrioventricular Junctional Rhythm|Bundle-Branch Block|Left Bundle-Branch Block|Heart Failure, Systolic|Block;Atrioventricular|Block; Arrhythmic|Block; Mobitz|Block, Heart|Block, Fascicular|Block Branch Bundle Left|Heart Failure，Congestive|Heart Arrhythmia |
| Interventions | DEVICE: Cardiac pacing - Conventional RV pacing|DEVICE: Cardiac pacing - Conduction System Pacing|DEVICE: Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)|DEVICE: Cardiac pacing - Epicardial pacing|DEVICE: Cardiac pacing - Leadless pacing |
| Sponsor | University Hospital of Ferrara |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 8400 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 01/01/2023 |
| Completion Date | 31/12/2034 |
| Locations | Ospedale Civico, azienda Ospedaliera di Palermo, Palermo, Italy| Policlinico Paolo Giaccone, Palermo, Italy, Giuseppe Coppola (docente Ente convenzionato PROMISE) |
| Study URL | https://clinicaltrials.gov/study/NCT06324682 |
| Study Title | Lynch Syndrome X-Talk of Enteral Mucosa With Immune System |
| NCT Number | NCT06708429 Other IDs: LYNX EYE 2023 |
| Conditions | Lynch Syndrome|Lynch Syndrome I|Lynch Syndrome II|Lynch Syndrome I (Site-specific Colonic Cancer)|HNPCC|HNPCC Gene Mutation|Hereditary Cancer Syndrome|Hereditary Cancer|MLH1 Gene Mutation|MLH1 Gene Deletion+Duplication|MLH1 Loss of Expression|MLH1 Gene Inactivation|MSH2 Gene Mutation|MSH2 Gene Deletion+Duplication|MSH2 Loss of Expression|MSH2 Gene Inactivation|MSH6 Gene Mutation|MSH6 Loss of Expression|MSH6 Gene Inactivation|PMS2 Gene Mutation|PMS2 Gene Inactivation|PMS2 Loss of Expression |
| Interventions | DIAGNOSTIC_TEST: LYNX EYE (Lynch syndrome X-Talk of Enteral mucosa with Immune System) |
| Sponsor | San Raffaele University |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 300 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 06/01/2023 |
| Completion Date | 06/01/2034 |
| Locations | Dipartimento di controllo qualità e rischio chimico biologico, AOOR Villa Sofia Cervello, Palermo, PM, Italy, Francesca Di Gaudio |
| Study URL | https://clinicaltrials.gov/study/NCT06708429 |
| Study Title | Multicenter Italian Cohort Study on Tuberculosis in Pediatric Age |
| NCT Number | NCT06289660 - Other IDs: PED-TB22 |
| Conditions | Tuberculosis Infection |
| Interventions | |
| Sponsor | Meyer Children's Hospital IRCCS |
| Sex | ALL |
| Age | CHILD, ADULT |
| Phases | |
| Enrollment | 1000 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 22/12/2022 |
| Completion Date | 03/01/2033 |
| Locations | prof.ssa Claudia Colomba, Ospedale dei Bambini "G.Di Cristina", Palermo, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT06289660 |
| Title | Multicenter, Nationwide, Observational, Prospective Study Based on the Development of a Primary Sclerosing Cholangitis Patient's Database Linked to a Biological Sample Storage |
| NCT Number |
NCT05618145 PSC_Database |
| Conditions | Primary Sclerosing Cholangitis |
| Interventions | Other: Clinical information |
| Sponsor/Collaborators | University of Milano Bicocca |
| Gender | All |
| Age | 17 Years and older (Child, Adult, Older Adult) |
| Phases | |
| Enrollment | 6000 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 21/10/2022 |
| Completion Date | 21/10/2032 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. Gastroenterologia, prof.ssa Vincenza Calvaruso |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT05618145 |
| Study Title | Italian Anderson Fabry Disease Cardiovascular Registry |
| NCT Number |
NCT06806813 Other IDs: RICMAF |
| Conditions | Fabry Disease |
| Interventions | |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna |
| Sex | ALL |
| Age | CHILD, ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 800 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 26/01/2022 |
| Completion Date | 31/12/2031 |
| Locations | Antonino Tuttolomondo, U.O.C. Medicina Interna con Stroke Care, Policlinico P. Giaccone, Palermo, Sicilia/Palermo, 90127, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT06806813 |
| Study Title | A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC) |
| NCT Number | NCT01848561 Other IDs: P11-282 |
| Conditions | Ulcerative Colitis (UC) |
| Interventions | |
| Sponsor | AbbVie |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 8250 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 29/04/2013 |
| Completion Date | 24/06/2030 |
| Locations | Dott.ssa Maria Cappello, Gastroenterologia , Direttore Prof. Calogero Cammà, Azienda Ospedaliera Universitaria Paolo Giaccone /ID# 141397, Palermo, 90127, Italy| A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 141392, Palermo, 90146, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT01848561 |
| Study Title | AutoInflammatory Disease Alliance Registry (AIDA) |
| NCT Number | NCT05200715 Other IDs: AIDA V.04 19.05.2021 |
| Conditions | Hereditary Autoinflammatory Diseases|Schnitzler Syndrome|Behcet Syndrome|PFAPA Syndrome|Still Disease|Autoinflammatory Syndrome, Unspecified|Uveitis|Scleritis|Vexas Syndrome |
| Interventions | OTHER: No intervention is foreseen by the protocol. |
| Sponsor | University of Siena |
| Sex | ALL |
| Age | CHILD, ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 3500 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 08/06/2020 |
| Completion Date | 08/06/2030 |
| Locations | ARNAS Ospedale Civico di Cristina Benfratelli, Palermo, Italy| Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy| prof.ssa Maria Cristina Maggio, University Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE) “G. D’Alessandro”, University of Palermo, Palermo, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT05200715 |
| Study Title | Fosfomycin I.v. for Treatment of Severely Infected Patients |
| NCT Number | NCT02979951 Other IDs: FORTRESS |
| Conditions | Bacterial Infections|Bone Diseases, Infectious|Osteomyelitis|Central Nervous System Bacterial Infections|Meningitis, Bacterial|Encephalitis|Brain Abscess|Urinary Tract Infections|Respiratory Tract Infections|Pneumonia, Bacterial|Skin Diseases, Bacterial|Soft Tissue Infections|Intraabdominal Infections|Sepsis|Bacteremia|Endocarditis, Bacterial |
| Interventions | |
| Sponsor | Sponsor: Infectopharm Arzneimittel GmbH - Collaborators: INPADS GmbH|Dr. Oestreich + Partner GmbH |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 1000 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 12/01/2016 |
| Completion Date | 12/01/2030 |
| Locations | Istituto Mediterraneo per i Trapianti Ismett IRCCS, Palermo, Italy| Policlinico Paolo Giaccone, Palermo, Italy, Antonio Cascio |
| Study URL | https://clinicaltrials.gov/study/NCT02979951 |
| Study Title | ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis) |
| NCT Number | NCT04561518 Other IDs: ALN-TTR02-013 |
| Conditions | Transthyretin-Mediated Amyloidosis|ATTR Amyloidosis |
| Interventions | |
| Sponsor | Alnylam Pharmaceuticals |
| Sex | ALL |
| Age | CHILD, ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 1500 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 23/11/2020 |
| Completion Date | 09/01/2030 |
| Locations | Alfredo Ruggero Galassi, Giuseppina Novo, Division of Cardiology, University Hospital Paolo Giaccone, Palermo, Italy; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE) "G. D'Alessandro", University of Palermo, Palermo, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT04561518 |
| Study Title | Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH) |
| NCT Number | NCT07447648 Other IDs: EVOLVE-HoFH |
| Conditions | Homozygous Familial Hypercholesterolemia (HoFH)|Coronary Computed Tomography Angiography |
| Interventions | |
| Sponsor/Collaborators | Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)/Ultragenyx Pharmaceutical Inc|CMV-Stat S.r.l.|Clinical Trial Consulting s.s. |
| Sex | ALL |
| Age | CHILD, ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 52 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: COHORT | Time Perspective: OTHER |
| Start Date | 30/04/2026 |
| Completion Date | 01/02/2029 |
| Locations |
Unité de Lipidologie et Prévention Cardiovasculaire, Centre de Compétence Dyslipidémies Rares (CEDRA), Service de Nutrition, Hôpital Pitié-Salpétriêre, Paris, France|Dipartimento Scienze-Cardiovascolari, AO "Sant'Anna e San Sebastiano" di Caserta, Caserta, Italy|U.O.C. di Medicina Interna, P.O. Nesima, ARNAS Garibaldi, Catania, Italy|Nefrologia e Emodialisi, Centro Aterosclerosi e Dislipidemie, Ospedale Bassini, ASST Nord Milano, Cinisello Balsamo, Italy|Malattie Aterotrombotiche, Azienda Ospedaliero Universitaria Careggi, Florence, Italy|DAI di Medicina Clinica, Centro di Riferimento Regionale di Lipidologia e Dislipidemie, AOU Federico II di Napoli, Naples, Italy|UOC Clinica Medica I, AOU di Padova, Padova, Italy| Prof. Angelo Baldassare Cefalù, U.O. Astanteria/MCAU AOU, Policlinico "Paolo Giaccone" di Palermo, Palermo, Italy| Centro per le Malattie Rare del Metabolismo dei Lipidi, Unità di Medicina Interna e Malattie Metaboliche, Dipartimento di Medicina Traslazionale e di Precisione Sapienza, Università di Roma, Roma, Italy|Medicina Interna, Ospedale Molinette, AOU Città della Salute e della Scienza, Torino, Italy|Amsterdam University Medical Center, Amsterdam UMC, locatie AMC, Amsterdam, Netherlands|Erasmus University Medical Center, Dr. Molewaterplein 40, Rotterdam, Netherlands|Ege University,Director of Lipid and Prevention Clinic, Department of Cardiology, Bornova, Turkey (Türkiye) |
| Study URL | https://clinicaltrials.gov/study/NCT07447648 |
| Study Title | National Database on Primary Biliary Cholangitis |
| NCT Number | NCT05151809 |
| Conditions | Primary Biliary Cholangitis |
| Interventions | OTHER: Clinical information |
| Sponsor | University of Milano Bicocca |
| Phases | |
| Enrollment | 6000 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 19/09/2019 |
| Completion Date | 24/01/2029 |
| Locations | UO gastroenterologia, Policlinico Paolo Giaccone, Palermo, Italy, prof. Calogero Cammà |
| Study URL | https://clinicaltrials.gov/study/NCT05151809 |
| Study Title | A Real-life Observational Study in Severe Eosinophilic Asthma Adult Participant Treated With Benralizumab in Italy |
| NCT Number | NCT07214753 Other Ids: D3250R00141 |
| Conditions | Severe Eosinophilic Asthma |
| Interventions | BIOLOGICAL: benralizumab |
| Sponsor/Collaborators | AstraZeneca |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 335 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 20/12/2025 |
| Completion Date | 31/12/2028 |
| Locations | Dott.ssa Alida Benfante, A O U Policlinico P. Giaccone, U.O.C. Pneumologia, Palermo, 90127, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT07214753 |
| Study Title | Observational Study on Long-term Use of Pegunigalsidase Alfa in Fabry Patients in a Real-world Setting |
| NCT Number | NCT07109375 Other IDs: CHIT-2401 |
| Conditions | Fabry Disease |
| Interventions | DRUG: pegunigalsidase alfa |
| Sponsor/Collaborators | Chiesi Italia |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 75 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 01/01/2026 |
| Completion Date | 01/11/2028 |
| Locations | Prof. Antonino Tuttolomondo, , U.O.C. Medicina Interna con Stroke Care, Policlinico P. Giaccone, Palermo, Sicilia/Palermo, 90127, Italy | AOU Federico II, Dipartimento di Nefrologia, Napoli, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT07109375 |
| Study Title | MONTEROSA - Italian Multicenter Observational Study to Evaluate Time to Clinical Hepatic Decompensation, Quality of Life, Effectiveness, and Safety of Tremelimumab Plus Durvalumab in Patients With Advanced or Unresectable Hepatocellular Carcinoma Who Have Received no Prior Systemic Treatment. |
| NCT Number | NCT07607769 Other IDs: D419CR00060 |
| Conditions | Hepatocellular Carcinoma |
| Interventions | DRUG: STRIDE |
| Sponsor | AstraZeneca |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 200 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: COHORT | Time Perspective: PROSPECTIVE |
| Start Date | 16/04/2026 |
| Completion Date | 31/10/2028 |
| Locations | Research site, Ancona, 60126, Italy|Research site, Bergamo, 24129, Italy|Research site, Foggia, 71122, Italy|Research site, Meldola, 47014, Italy|Research site, Milan, 20122, Italy|Research site, Milan, 20162, Italy|Research site, Modena, 41124, Italy|Research site, Naples, 80131, Italy|Research site, Padova, 35100, Italy Prof. Calogero Cammà, Gastroenterologia, Azienda Ospedaliera Universitaria Paolo Giaccone, Research site, Palermo, 90127, Italy Research site, Pisa, 56126, Italy|Research site, Pozzuoli, 80078, Italy|Research site, Roma, 00168, Italy|Research site, Rozzano, 20089, Italy|Research site, Torino, 10126, Italy|Research site, Verona, 37134, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT07607769 |
| Study Title | Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab |
| NCT Number |
NCT07330245 Other IDs: D3461R00093 |
| Study Status | RECRUITING |
| Conditions | Lupus Erythematosus, Systemic |
| Interventions | BIOLOGICAL: Anifrolumab |
| Sponsor/Collaborators | AstraZeneca |
| Sex | ALL |
| Age | CHILD, ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 218 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 31/12/2025 |
| Completion Date | 30/09/2028 |
| Locations | Prof.ssa Giuliana Guggino, UOC di Reumatologia, Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", Palermo, 90127, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT07330245 |
| Study Title | A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes |
| NCT Number | NCT07112339 Other IDs: NN1436-7727|U1111-1302-4943|2024-520068-32 |
| Conditions | Diabetes Mellitus, Type 2 |
| Interventions | DRUG: Insulin icodec|DRUG: Basal insulin analogues |
| Sponsor | Novo Nordisk A/S |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | PHASE4 |
| Enrollment | 586 |
| Study Type | INTERVENTIONAL |
| Study Design | Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT |
| Start Date | 15/08/2025 |
| Completion Date | 31/08/2028 |
| Locations | prof. Silvio Buscemi, responsabile del programma di Nutrizione Clinica, Obesità e Malattie del Metabolismo, Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone - Presidio Villa Belmonte, Palermo, Sicily, 90127, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT07112339 |
| Study Title | A Non-Interventional Clinical Study to Evaluate Long-Term Safety and Effectiveness of HUMIRA (Adalimumab) in Pediatric Patients With Moderately to Severely Active Crohn's Disease (CD) |
| NCT Number | NCT02130362 Other IDs: P11-292 |
| Conditions | Crohn's Disease |
| Interventions | |
| Sponsor | AbbVie |
| Sex | ALL |
| Age | CHILD |
| Phases | |
| Enrollment | 1446 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 28/08/2014 |
| Completion Date | 03/02/2028 |
| Locations | U.O. Gastroenterologia - Malattie Infiammatorie Croniche Intestinali, Prof. Calogero Cammà, Policlinico Paolo Giaccone /ID# 138410, Palermo, Sicilia, 90127, Italy| A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 152684, Palermo, 90146, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT02130362 |
| Study Title | Study to Assess Speed of Onset and Durability of Effectiveness of Upadacitinib in Adult Participants With Moderate to Severe Crohn's Disease (CD) in Real World Clinical Practice. |
| NCT Number | NCT05930275 Other IDs: P23-899 |
| Conditions | Crohn's Disease |
| Interventions | |
| Sponsor | AbbVie |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 1200 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 19/02/2024 |
| Completion Date | 09/01/2028 |
| Locations | Prof. Camma' Calogero, UOC Gastroenterologia, Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone /ID# 275093, Palermo, 90127, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT05930275 |
| Title | Assessment of Guselkumab (Tremfya) and IL-17 Inhibitor Therapies in Patients With Psoriatic Arthritis in Routine Clinical Practice; A Prospective, Observational Cohort Study |
| NCT Number | NCT05049798 |
| Conditions | Intervention/treatment Arthritis, Psoriatic |
| Interventions | Drug: Guselkumab Drug: IL-17i |
| Sponsor/Collaborators | Janssen Pharmaceutica N.V., Belgium |
| Gender | All |
| Age | 18 Years and older (Adult, Older Adult) |
| Phases | |
| Enrollment | 1300 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 25/08/2021 |
| Completion Date | 07/12/2027 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. Dermatologia, Prof.ssa Maria Rita Bongiorno |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT05049798 |
| Study Title | A Study of Guselkumab in Participants With Psoriatic Arthritis (PsA) in a Real-World Setting |
| NCT Number | NCT07220824 Other IDs: CNTO1959PSA4020|CNTO1959PSA4020 |
| Conditions | Arthritis, Psoriatic |
| Interventions | |
| Sponsor | Janssen Research & Development, LLC |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 200 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 12/04/2025 |
| Completion Date | 30/09/2027 |
| Locations | Giuliana Guggino, Direttore U.O. di Reumatologia, Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone, Palermo, 90127, Italy |
| Study URL | https://clinicaltrials.gov/study/NCT07220824 |
| Study Title | Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs) |
| NCT Number | NCT07457580 Other Ids: OBS20675|U111-1322-8196 |
| Conditions | Type 1 Diabetes |
| Interventions | DRUG: Teplizumab |
| Sponsor | Sanofi |
| Sex | ALL |
| Age | CHILD, ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 60 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: COHORT | Time Perspective: RETROSPECTIVE |
| Start Date | 16/03/2026 |
| Completion Date | 30/11/2026 |
| Locations |
Investigational Site Number: 0560001, Leuven, 3000, Belgium|Investigational Site Number: 2500001, Bron, 69677, France|Investigational Site Number: 2500003, Paris, 75014, France|Investigational Site Number: 2500002, Paris, 75015, France|Investigational Site Number: 2760002, Frankfurt, 60596, Germany|Investigational Site Number: 2760001, Hanover, 30173, Germany|Investigational Site Number: 3800001, Ancona, 60123, Italy| Dott.ssa Valentina Guarnotta, Unita Operativa: Malattie Endocrine, del Ricambio e della Nutrizione, AOUP "P. Giaccone", Investigational Site Number: 3800003, Palermo, 90127, Italy| Investigational Site Number: 3800002, Verona, 37126, Italy|Investigational Site Number: 7240001, Madrid, 28034, Spain|Investigational Site Number: 7240002, Madrid, 28046, Spain|Investigational Site Number: 7240003, Zaragoza, 50009, Spain|Investigational Site Number: 8260001, Birmingham, B4 6NH, United Kingdom|Investigational Site Number: 8260002, London, E1 1BB, United Kingdom |
| Study URL | https://clinicaltrials.gov/study/NCT07457580 |
| Title | Observational Study on the Diagnosis and Management of Chronic Lymphocytic Leukemia (CLL) in Italy by Gruppo Italiano Malattie EMatologiche Dell'Adulto (GIMEMA) |
| NCT Number | NCT04867915 |
| CLL2121 | |
| Conditions | Chronic Lymphocytic Leukemia |
| Small Lymphocytic Lymphoma | |
| MBL-CLL - Monoclonal B-Cell Lymphocytosis Chronic Lymphocytic Leukaemia-Type | |
| Interventions | |
| Sponsor/Collaborators | Gruppo Italiano Malattie EMatologiche dell'Adulto |
| Gender | All |
| Age | 18 Years and older (Adult, Older Adult) |
| Phases | |
| Enrollment | 12500 participants |
| Study Type | Observational |
| Study Designs | Case-Only |
| Start Date | 13/10/2021 |
| Completion Date | 31/10/2026 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. di Ematologia, Prof. Sergio Siragusa |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT04867915 |
| Title | Patient-Reported Outcomes in PHiladelphia-nEgative Cytogenetic mYeloproliferative Neoplasms (PROPHECY): A GIMEMA Observational Registry for Italian MPN Patients |
| NCT Number | NCT04378855 |
| QoL MPN0118 | |
| Conditions | Myeloproliferative Neoplasm |
| Other: Questionnaire | |
| Interventions | |
| Sponsor/Collaborators | Gruppo Italiano Malattie EMatologiche dell'Adulto |
| Gender | All |
| Age | 18 Years and older (Adult, Older Adult) |
| Phases | Phase 2 |
| Enrollment | 576 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 30/09/2020 |
| Completion Date | 31/10/2026 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. di Ematologia, Prof. Sergio Siragusa |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT04378855 |
| Study Title | European and North Indian Cohort of KaWasaki dIsease |
| NCT Number | NCT06305611 Other IDs: KIWI |
| Conditions | Kawasaki Disease |
| Interventions | |
| Sponsor | Meyer Children's Hospital IRCCS |
| Sex | ALL |
| Age | CHILD |
| Phases | |
| Enrollment | 103 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: p |
| Start Date | 13/07/2021 |
| Completion Date | 30/10/2026 |
| Locations | Maria Cristina Maggio e Giovanni Corsello, P.O. "Giovanni Di Cristina", Palermo, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT06305611 |
| Study Title | Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia |
| NCT Number | NCT04579367 Other IDs: DSE-BMP-01-20-EU |
| Conditions | Hypercholesterolemia|Mixed Dyslipidemia |
| Interventions | DRUG: Bempedoic acid and/or its fixed-dose combination with ezetimibe |
| Sponsor | Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company |
| Sex | ALL |
| Age | ADULT, OLDER_ADULT |
| Phases | |
| Enrollment | 5000 |
| Study Type | OBSERVATIONAL |
| Study Design | Observational Model: |Time Perspective: |
| Start Date | 15/01/2021 |
| Completion Date | 30/10/2026 |
| Locations | prof. Maurizio Averna, Medicina Interna e Dislipidemie Genetiche, Dir. Prof. Carlo Maria Barbagallo, A.O.U. Policlinico "P. Giaccone", Palermo, 90127, Italy| Casa di Cura Triolo Zancla Hospital, Palermo, 90133, Italy| |
| Study URL | https://clinicaltrials.gov/study/NCT04579367 |
| Title | Prospective Observational Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera |
| NCT Number | NCT05548062 CINC424BIT01 |
| Conditions | Intervention/treatment Polycythemia Vera |
| Interventions | Other: Hydroxyurea Other: Ruxolitinib |
| Sponsor/Collaborators | Novartis ( Novartis Pharmaceuticals ) |
| Gender | All |
| Age | 18 Years to 99 Years (Adult, Older Adult) |
| Phases | |
| Enrollment | 300 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 02/03/2023 |
| Completion Date | 30/09/2026 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. di Ematologia, Prof. Sergio Siragusa |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT05548062 |
| Title | Non-Interventional Study of the Change in Joint Health in Adult Patients With Haemophilia A After Switching to Prophylaxis With Turoctocog Alfa Pegol (N8-GP) |
| NCT Number | NCT05621746 |
| NN7088-4928 | |
| Conditions | Intervention/treatment |
| Haemophilia A | |
| Drug: Esperoct | |
| Interventions | |
| Sponsor/Collaborators | Novo Nordisk A/S |
| Gender | Male |
| Age | 18 Years and older (Adult, Older Adult) |
| Phases | |
| Enrollment | 100 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 23/11/2022 |
| Completion Date | 30/06/2026 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. Ematologia, prof.ssa Mariasanta Napolitano |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT05621746 |
| Title | Real-world Effectiveness and Treatment Patterns of Upadacitinib in Monotherapy or Used in Combination With Methotrexate in Active Psoriatic Arthritis Patients |
| NCT Number | NCT05616871 P22-897 |
| Conditions | Psoriatic Arthritis |
| Interventions | |
| Sponsor/Collaborators | AbbVie |
| Gender | All |
| Age | 18 Years and older (Adult, Older Adult) |
| Phases | |
| Enrollment | 450 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 15/12/2022 |
| Completion Date | 14/06/2026 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT05616871 |
| Title | Quality Of Life On Elderly Patients With Low Grade Non-Hodgkin Lymphoma Treated With Immunotherapy Or Immunochemotherapy And/Or Radiotherapy: An Observational Prospective Study Of The Fondazione Italiana Linfomi |
| NCT Number | NCT05524298 |
| FIL_QoL-ELDIND | |
| Conditions | Low Grade Non-Hodgkin's Lymphoma, Adult |
| Interventions | |
| Sponsor/Collaborators | Fondazione Italiana Linfomi ONLUS |
| Gender | All |
| Age | 70 Years and older (Older Adult) |
| Phases | |
| Enrollment | 150 participants |
| Study Type | Observational |
| Study Designs | Cohort |
| Start Date | 01/09/2022 |
| Completion Date | 01/02/2026 |
| Locations | A.O.U. Policlinico P. Giaccone di Palermo, U.O.C. di Ematologia, Dott.ssa Salvatrice Mancuso |
| URL | https://www.clinicaltrials.gov/ct2/show/NCT05524298 |
| Study Title |
Study for Elderly (≥ 65 Years) Patients With Classical Hodgkin Lymphoma Undergoing CGA at Diagnosis Raccolta prospettica di dati di pazienti anziani (≥65 aa) con linfoma di Hodgkin di tipo classico sottoposti al momento della diagnosi a valutazione geriatrica multidimensionale (VGM) |
| NCT Number |
NCT03552003 Other IDs: FIL_ELDHL |
| Conditions | Classical Hodgkin Lymphoma |
| Interventions | Other: Treatment for clinical practise |
| Sponsor |
Fondazione Italiana Linfomi - ETS |
| Sex | ALL |
| Age | 65 Years and older (Older Adult) |
| Phases | |
| Enrollment | 400 |
| Study Type | Observational |
| Study Design | Observational Model : Cohort Time Perspective: Prospective Biospecimen Retention: Samples Without DNA Biospecimen Description: Mandatory:
Optional:
|
| Start Date | 10/08/2018 |
| Completion Date | 31/01/2026 |
| Locations | A.O. Univ. Policlinico "Paolo Giaccone", Ematologia, prof.ssa Salvatrice Mancuso |
| Study URL | https://clinicaltrials.gov/study/NCT03552003 |
