Salta al contenuto principale
Passa alla visualizzazione normale.

ANTONELLA D'ANNEO

Curriculum e ricerca

Insegnamenti

Anno accademico Codice della materia Nome della materia CFU Corso di studi
2020/2021 01560 BIOCHIMICA CON ESERCITAZIONI 9 SCIENZE BIOLOGICHE
2020/2021 18660 BIOCHIMICA TOSSICOLOGICA (MODULO) 3 SCIENZE BIOLOGICHE
2020/2021 05176 METODOLOGIE BIOCHIMICHE 6 BIOLOGIA MOLECOLARE E DELLA SALUTE

Pubblicazioni

Data Titolo Tipologia Scheda
2019 WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner Articolo in rivista Vai
2019 Phenolic composition of hydrophilic extract of manna from sicilian Fraxinus angustifolia vahl and its reducing, antioxidant and anti-inflammatory activity in vitro Articolo in rivista Vai
2019 Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway Articolo in rivista Vai
2019 The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells Articolo in rivista Vai
2019 Novel 4-(3-phenylpropionamido), 4-(2-phenoxyacetamido) and 4-(cinnamamido) substituted benzamides bearing the pyrazole or indazole nucleus: synthesis, biological evaluation and mechanism of action Articolo in rivista Vai
2018 Ethanol promotes survival and tumor progression of colon cancer cells Contributo in atti di convegno pubblicato in volume Vai
2018 The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer Articolo in rivista Vai
2018 Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review Articolo in rivista Vai
2018 Sicilian litchi fruit extracts induce autophagy versus apoptosis switch in human colon cancer cells Articolo in rivista Vai
2017 Derivati policiclici con struttura complessa dotati di attività antiproliferativa Abstract in atti di convegno pubblicato in volume Vai
2017 Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence. Articolo in rivista Vai
2017 Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action Articolo in rivista Vai
2017 Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways. Articolo in rivista Vai
2017 Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas Articolo in rivista Vai
2016 Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound Articolo in rivista Vai
2016 Synthesized benzamido derivatives exert antiproliferative effects by DNA damage and ROS generation. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2016 Isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives endowed with anti-proliferative Activity. Abstract in atti di convegno pubblicato in volume Vai
2016 The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms. Articolo in rivista Vai
2016 The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells Articolo in rivista Vai
2016 Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2016 Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence Abstract in atti di convegno pubblicato in rivista Vai
2015 Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality Articolo in rivista Vai
2015 The Synergistic Effect of SAHA and Parthenolide in MDA-MB231 Breast Cancer Cells Articolo in rivista Vai
2015 Possible regulatory mechanisms responsible for the high expression of serpin protease inhibitor PI-9 in ER+ -derived breast cancer stem cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 WIN-induced vesiculation cooperates to the inhibition of osteosarcoma cell migration Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 ER+-derived breast cancer stem cells reveal a high expression of the serpin protease inhibitor PI-9. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 Different modulatory effect of the synthetic cannabinoid WIN55,212-2 on tumor cell migration. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 Il sostegno e il miglioramento delle coltivazioni sub-tropicali in Sicilia traggono vantaggio dallo studio e dalla promozione delle loro proprietà nutrizionali. Contributo in atti di convegno pubblicato in volume Vai
2014 Synergistic effect of the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide in triple negative breast cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 The synergistic effect exerted by the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide on triple negative breast canc er cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 ATTIVITÀ ANTIPROLIFERATIVA DI UN DERIVATO POLICICLICO CON STRUTTURA COMPLESSA Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 The HDAC inhibitor SAHA synergistically stimulates the cytotoxic effect induced by Parthenolide in MDA-MB231 cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 Heat shock protein 60 (Hsp60) modulation by the Histon Deacetylase Inhibitor (HDAC-i) SAHA in mucoepidermoid tumor H292 cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells Articolo in rivista Vai
2014 MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells Articolo in rivista Vai
2014 Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells. Articolo in rivista Vai
2013 Okadaic acid-Parthenolide combination at subtoxic doses induces potent synergistic apoptotic effects in human retinoblastoma Y79 cells by upregulating PTEN. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells. Articolo in rivista Vai
2013 Il partenolide stimola la produzione di ROS e autofagia in cellule di carcinoma mammario MDA-MB231.Il suo analogo solubile DMAPT inibisce la crescita e le metastasi di xenotrapianti di tumori mammari. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Synergistic cytotoxic interaction of the HDAC inhibitor SAHA with the natural compound parthenolide in MDA-MB231 breast cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells. Articolo in rivista Vai
2013 RB1 in cancer: Different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis. Articolo in rivista Vai
2013 Differentiation of human osteosarcoma 3AB-OS stem-like cells in derivatives of the three primary germ layers as an useful in vitro model to develop several purposes Articolo in rivista Vai
2013 In human retinoblastoma Y79 cells okadaic acid–parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player. Articolo in rivista Vai
2013 Parthenolide induces EGF receptor phosphorylation and superoxide anion production in MDA-MB231 breast cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. Articolo in rivista Vai
2012 Parthenolide induces caspase-independent cell death mediated by AIF in osteosarcoma and melanoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Modeling human osteosarcoma in mice through 3AB-OS cancer stem cell xenografts Articolo in rivista Vai
2012 3AB-OS, a human osteosarcoma stem-like cell line, potential model for studying cancer Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Parthenolide induces caspase-independent cell death in osteosarcoma, melanoma and breast cancer cells through the induction of oxidative stress. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Il partenolide induce morte in cellule di osteosarcoma umano MG63 mediante un meccanismi caspasi-indipendente, mediato da AIF. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Evaluation of the in vitro and in vivo antineoplastic effects of Parthenolide on MDA-MB231 breast cancer cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Parthenolide induces caspase-independent and AIF mediated cell death in tumor cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2011 Phosphatidylinositol-3-kinase activity during in vitro dendritic cell generation determines suppressive or stimulatory capacity. Articolo in rivista Vai
2011 Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. Articolo in rivista Vai
2011 The mechanism of parthenolide-induced cell death in tumor cell lines. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2011 Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(-) CD25(high) FoxP3(+) regulatory T cells. Articolo in rivista Vai
2010 Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt. Articolo in rivista Vai
2010 Anti tumor action of the natural compound parthenolide Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Il partenolide sensibilizza le cellule di epatocarcinoma all'apoptosi indotta da TRAIL Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Composizioni farmaceutiche per il trattamento di tumori epatici Brevetto Vai
2009 Parthenolide sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Synergistic interaction between Parthenolide and TRAIL induces apoptosis in human hepatocarcinoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation Articolo in rivista Vai
2009 Karyotypic Complexity and Chromosomal Aberrations In Human Embryonic Cancer Stem Cells 3AB-OS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2008 Immuno-Fluorescence (IF) on interphase polytene chromosomes of Drosophila melanogaster Capitolo o Saggio Vai
2008 HISTONE DEACETYLASE INHIBITORS SENSITIZE HEPATOMA CELLS TO TRAIL_INDUCED APOPTOSIS Proceedings (TIPOLOGIA NON ATTIVA) Vai
2008 The sensitization of HepG2 and HT29 cells to TRAIL-induced apoptosis by histone deacetylase inhibitors is mediated by down-regulation of AKT and NF-kB. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2008 The mechanism by which histone deacetylase inhibitors sensitize hepatoma and colon cancer cells to TRAIL-induced apoptosis Proceedings (TIPOLOGIA NON ATTIVA) Vai
2008 Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. Articolo in rivista Vai
2008 Polymerase Chain Reaction (PCR) Capitolo o Saggio Vai
2007 SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. Articolo in rivista Vai
2007 THE APOPTOTIC EFFECT INDUCED IN HepG2 CELLS BY INHIBITORS OF HISTONE DEACETYLASES IS CORRELATED WITH ACETYLATION OF p53 AND HISTONES. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 The cannabinoid system and its potential therapeutic applications in cancer. Monografia Vai
2007 Histone deacetylase inhibitors: Epigenetic drugs acting by pleiotropic apoptotic mechanism in tumor cells and highly potent in combination with other antitumor agents. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 Role of the acetylation of p53 and histones in SAHA-induced apoptosis in human hepatoma HepG2 cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Apoptosis induced by the histone deacetylase inhibitor SAHA in human colon adenocarcinoma cell line HT29 Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 THE ROLE OF THE EXTRINSIC PATHWAY OF APOPTOSIS IN THE EFFECT INDUCED BY SAHA IN HUMAN HEPATOMA CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 “Effects of histone deacetylase inhibitors in human hepatoma cells and synergistic apoptotic interaction with the proteasome inhibitor Bortezomib” Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Gene therapy for type 1 diabetes: is it ready for the clinic? Articolo in rivista Vai
2006 Differentiation induced by 3-aminobenzamide in human osteosarcoma MG-63 cells is mediated by the inhibition of the Wnt/β-catenin pathway Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways Articolo in rivista Vai
2006 “Acetilazione di p53 e degli istoni nell’apoptosi indotta dal SAHA in cellule di epatoma umano HepG2” Proceedings (TIPOLOGIA NON ATTIVA) Vai
2005 Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. Articolo in rivista Vai
2005 JNK AND AP-1 MEDIATE APOPTOSIS INDUCED BY BORTEZOMIB IN HEPATOMA HEPG2 CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2005 THE APOPTOTIC EFFECT EXERTED IN HUMAN HEPATOMA CELLS BY THE INHIBITOR OF HISTONE DEACETYLASE SAHA EITHER ALONE OR IN COMBINATION WITH BORTEZOMIB. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2005 SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Sodium butyrate induces apoptosis in human hepatoma cells by a mitochondria/caspase pathway, associated with degradation of beta-catenin, pRb and Bcl-XL. Articolo in rivista Vai
2004 Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL. Articolo in rivista Vai
2004 Differentiative pathway induced by 3-aminobenzamide in MG-63 human osteosarcoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Proteasome inhibitor Velcade induces apoptosis in hepatoma HepG2 cells stimulating both the extrinsic and the intrinsic apoptotic pathways. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2003 Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb Articolo in rivista Vai
2003 The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells Articolo in rivista Vai
2003 Apoptosis meets proteasome, an invaluable therapeutic target of anticancer drugs Articolo in rivista Vai
2002 Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-Xs and activation of caspase-3 Articolo in rivista Vai
2001 pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. Articolo in rivista Vai
2001 Sodium phenylbutyrate induces apoptosis in human retinoblastoma Y79 cells: The effect of combined treatment with the topoisomerase I-inhibitor topotecan Articolo in rivista Vai