Microbiological testing of adults hospitalised with community-acquired pneumonia: An international study
- Autori: Carugati M.; Aliberti S.; Reyes L.F.; Sadud R.F.; Irfan M.; Prat C.; Soni N.J.; Faverio P.; Gori A.; Blasi F.; Restrepo M.I.; Aruj P.K.; Attorri S.; Barimboim E.; Caeiro J.P.; Garzon M.I.; Cambursano V.H.; Ceccato A.; Chertcoff J.; Diaz A.C.; De Vedia L.; Ganaha M.C.; Lambert S.; Lopardo G.; Luna C.M.; Malberti A.G.; Morcillo N.; Tartara S.; Pensotti C.; Pereyra B.; Scapellato P.G.; Stagnaro J.P.; Shah S.; Lotsch F.; Thalhammer F.; Anseeuw K.; Francois C.A.; Van Braeckel E.; Vincent J.L.; Djimon M.Z.; Bashi J.; Dodo R.; Nouer S.A.; Chipev P.; Encheva M.; Miteva D.; Petkova D.; Balkissou A.D.; Yone E.W.P.; Ngahane B.H.M.; Shen N.; Xu J.-F.; Rico C.A.B.; Buitrago R.; Paternina F.J.P.; Ntumba J.-M.K.; Carevic V.V.; Jakopovic M.; Jankovic M.; Matkovic Z.; Mitrecic I.; Jacobsson M.L.B.; Christensen A.B.; Bodtger U.C.H.; Meyer C.N.; Jensen A.V.; Baunbaek-Knudsen G.; Petersen P.T.; Andersen S.; Abd El-Wahhab I.E.-S.; Morsy N.E.; Shafiek H.; Sobh E.; Abdulsemed K.A.; Bertrand F.; Brun-Buisson C.; De Montmollin E.; Fartoukh M.; Messika J.; Tattevin P.; Khoury A.; Ebruke B.; Dreher M.; Kolditz M.; Meisinger M.; Pletz M.W.; Hagel S.; Rupp J.; Schaberg T.; Spielmanns M.; Creutz P.; Suttorp N.; Siaw-Lartey B.; Dimakou K.; Papapetrou D.; Tsigou E.; Ampazis D.; Kaimakamis E.; Gaga M.; Bhatia M.; Dhar R.; D'Souza G.; Garg R.; Koul P.A.; Mahesh P.A.; Jayaraj B.S.; Narayan K.V.; Udnur H.B.; Krishnamurthy S.B.; Kant S.; Swarnakar R.; Limaye S.; Salvi S.; Golshani K.; Keatings V.M.; Martin-Loeches I.; Maor Y.; Strahilevitz J.; Battaglia S.; Carrabba M.; Ceriana P.; Confalonieri M.; Monforte A.D.; Del Prato B.; De Rosa M.; Fantini R.; Fiorentino G.; Gammino M.A.; Menzella F.; Milani G.; Nava S.; Palmiero G.; Petrino R.; Gabrielli B.; Rossi P.; Sorino C.; Steinhilber G.; Zanforlin A.; Franzetti F.; Morosi M.; Monge E.; Carone M.; Patella V.; Scarlata S.; Comel A.; Kurahashi K.; Bacha Z.A.; Ugalde D.B.; Zuniga O.C.; Villegas J.F.; Medenica M.; Van De Garde E.M.W.; Mihsra D.R.; Medicine I.; Shrestha P.; Ridgeon E.; Awokola B.I.; Nwankwo O.N.O.; Olufunlola A.B.; Olumide S.; Ukwaja K.N.; Minarowski L.; Szymon S.; Froes F.; Leuschner P.; Meireles M.; Ferrao C.; Neves J.; De Medicina S.; Ravara S.B.; Brocovschii V.; Ion C.; Rusu D.; Tom C.; Chirita D.; Dorobat C.M.; Birkun A.; Kaluzhenina A.; Almotairi A.; Bukhary Z.A.A.; Edathodu J.; Fathy A.; Enani A.M.A.; Mohamed N.E.; Memon J.U.; Bella A.; Bogdanovic N.; Milenkovic B.; Pesut D.; Feldman C.; Yum H.K.; Borderias L.; Garcia N.M.B.; Alarcon H.C.; Cilloniz C.; Torres A.; Diaz-Brito V.; Casas X.; Gonzalez A.E.; Fernandez-Almira M.L.; Gallego M.; Gaspar-Garcia I.; Del Castillo J.G.; Victoria P.J.; Martinez E.L.; De Molina R.M.; Marcos P.J.; Menendez R.; Pando-Sandoval A.; Aymerich C.P.; Rello J.; Moyano S.; Sanz F.; Sibila O.; Rodrigo-Troyano A.; Sole-Violan J.; Uranga A.; Van Boven J.F.M.; Torra E.V.; Pujol J.A.; Fiogbe A.A.; Yangui F.; Bilaceroglu S.; Dalar L.; Yilmaz U.; Bogomolov A.; Elahi N.; Feneley A.; Ions R.; Skeemer J.; Woltmann G.; Hancock C.; Hill A.T.; Rudran B.; Ruiz-Buitrago S.; Campbell M.; Whitaker P.; Youzguin A.; Singanayagam A.; Allen K.S.; Brito V.; Dietz J.; Dysart C.E.; Kellie S.M.; Franco-Sadud R.A.; Meier G.; Holland T.L.; Bergin S.P.; Kheir F.; Landmeier M.; Lois M.; Nair G.B.; Patel H.; Reyes K.; Rodriguez-Cintron W.; Saito S.; Noda J.; Hinojosa C.I.; Levine S.M.; Angel L.F.; Anzueto A.; Whitlow K.S.; Hipskind J.; Sukhija K.; Totten V.; Wunderink R.G.; Shah R.D.; Mateyo K.J.; Dhasmana D.J.; Noriega L.; Alvarado E.; Aman M.; Labra L.
- Anno di pubblicazione: 2018
- Tipologia: Articolo in rivista
- OA Link: http://hdl.handle.net/10447/534649
Abstract
This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.