2024 |
Chaperoning system: Intriguing target to modulate the expression of CFTR in cystic fibrosis |
Articolo in rivista |
Vai |
2024 |
Computational Approaches and Drug Discovery: Where Are We Going? |
Articolo in rivista |
Vai |
2024 |
Natural products as non-covalent and covalent modulators of the KEAP1/NRF2 pathway exerting antioxidant effects |
Articolo in rivista |
Vai |
2023 |
Treatment of Complex Regional Pain Syndrome (Crps): New Perspectives in the Use of Sulfonamides as Modulators of P2x Receptors |
Review essay (rassegna critica) |
Vai |
2023 |
Aminoquinolines: Fluorescent sensors to DNA – A minor groove probe. Experimental and in silico studies |
Articolo in rivista |
Vai |
2023 |
Synthesis of new antiproliferative 1,3,4-substituted-pyrrolo[3,2-c]quinoline derivatives, biological and in silico insights |
Articolo in rivista |
Vai |
2023 |
Exploring the new non-covalent immunoproteasome inhibitors of β1i /β5i subunits: Virtual screening and in vitro test |
Abstract in atti di convegno pubblicato in volume |
Vai |
2023 |
Immuno-oncological treatment of Non-Small-Cell Lung Cancer (NSCLC)
in advanced stage with Nivolumab |
Articolo in rivista |
Vai |
2023 |
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific
2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in
nonsense mutated CFTR |
Articolo in rivista |
Vai |
2023 |
Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome |
Articolo in rivista |
Vai |
2023 |
Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors |
Articolo in rivista |
Vai |
2023 |
Non-covalent immunoproteasome inhibitors: virtual screening and in vitro test on β1i /β5i subunits |
Abstract in atti di convegno pubblicato in volume |
Vai |
2022 |
Sulfonamide moiety as "molecular chimera" in the design of new drugs |
Review essay (rassegna critica) |
Vai |
2022 |
In Silico Design, Synthesis and Biological Evaluation of Anticancer Arylsulfonamide Endowed with Anti-Telomerase Activity |
Articolo in rivista |
Vai |
2021 |
Immunoproteasome and Non-Covalent Inhibition: Exploration by Advanced Molecular Dynamics and Docking Methods |
Articolo in rivista |
Vai |
2021 |
Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
Articolo in rivista |
Vai |
2021 |
Preface to "Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics" |
Prefazione/Postfazione |
Vai |
2021 |
Antiproliferative properties and g-quadruplex-binding of symmetrical naphtho[1,2-b:8,7-b’]dithiophene derivatives |
Articolo in rivista |
Vai |
2021 |
Exploring the non-covalent ligand-binding mechanism on immunoproteasome by enhanced Molecular Dynamics |
Abstract in atti di convegno pubblicato in volume |
Vai |
2021 |
Evaluation of the IKKβ Binding of Indicaxanthin by Induced-Fit Docking, Binding Pose Metadynamics, and Molecular Dynamics |
Articolo in rivista |
Vai |
2020 |
The in silico fischer lock-and-key model: The combined use of molecular descriptors and docking poses for the repurposing of old drugs |
Capitolo o Saggio |
Vai |
2020 |
Investigation on quantitative structure-activity relationships of 1,3,4-oxadiazole derivatives as potential telomerase inhibitors |
Articolo in rivista |
Vai |
2020 |
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) |
Articolo in rivista |
Vai |
2020 |
A definitive pharmacophore modelling study on CDK2 ATP pocket binders: Tracing the path of new virtual high-throughput screenings |
Articolo in rivista |
Vai |
2020 |
Comparing molecular dynamics-derived pharmacophore models with docking: A study on CDK-2 inhibitors |
Articolo in rivista |
Vai |
2020 |
Exploring the SARS-CoV-2 proteome in the search of potential inhibitors via structure-based pharmacophore modeling/docking approach |
Articolo in rivista |
Vai |
2019 |
Indicaxanthin, a multi-target natural compound from Opuntia ficus-indica fruit: From its poly-pharmacological effects to biochemical mechanisms and molecular modelling studies |
Articolo in rivista |
Vai |
2019 |
TOWARD ENRICHED VHTS FOR CDK2 INHIBITORS: MOLECULAR DYNAMICS, PHARMACOPHORE MODELLING, AND DOCKING |
Abstract in atti di convegno pubblicato in volume |
Vai |
2019 |
Deciphering the Nonsense Readthrough Mechanism of Action of Ataluren: An in Silico Compared Study |
Articolo in rivista |
Vai |
2019 |
Uno studio comparativo in silico sui possibili target di Ataluren e analoghi farmaci promotori di readthrough di codoni di stop prematuri |
Contributo in atti di convegno pubblicato in volume |
Vai |
2019 |
Predicting Skin Permeability by Means of Computational Approaches: Reliability and Caveats in Pharmaceutical Studies |
Review essay (rassegna critica) |
Vai |
2018 |
Reverse screening on indicaxanthin from Opuntia ficus-indica as natural chemoactive and chemopreventive agent |
Articolo in rivista |
Vai |
2018 |
Consensus modelling and molecular dynamics studies for the identification of novel telomerase inhibitors as anti-cancer agents |
Poster pubblicato in volume |
Vai |
2018 |
The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA |
Articolo in rivista |
Vai |
2018 |
Reverse Screening on Indicaxanthin from Opuntia ficus-indica as natural chemoactive and chemopreventive agent |
Abstract in atti di convegno pubblicato in volume |
Vai |
2017 |
Conf-VLKA: A structure-based revisitation of the Virtual Lock-and-key Approach |
Articolo in rivista |
Vai |
2017 |
Common Hits Approach: Combining Pharmacophore Modeling and Molecular Dynamics Simulations |
Articolo in rivista |
Vai |
2017 |
Micelles of the chiral biocompatible surfactant (1R,2S)-dodecyl-(2-hydroxy-1-methyl-2-phenylethyl)dimethylammonium bromide (DMEB): Molecular dynamics and fragmentation patterns in the gas phase |
Articolo in rivista |
Vai |
2017 |
A Molecular Dynamics-Shared Pharmacophore Approach to Boost Early-Enrichment Virtual Screening: A Case Study on Peroxisome Proliferator-Activated Receptor α |
Articolo in rivista |
Vai |
2017 |
Recent advances on CDK inhibitors: An insight by means of in silico methods |
Articolo in rivista |
Vai |
2017 |
The Molecular dYnamics SHAred PharmacophorE (MYSHAPE) approacha new tool to arise docking and pharmacophore modeling performance: virtues and vices |
Poster pubblicato in volume |
Vai |
2017 |
Micelles, Rods, Liposomes, and Other Supramolecular Surfactant Aggregates: Computational Approaches |
Articolo in rivista |
Vai |
2016 |
Design, synthesis and preliminary evaluation of dopamine-amino acid conjugates as potential D1 dopaminergic modulators |
Articolo in rivista |
Vai |
2016 |
A dynamic-common pharmacophore approach to improve virtual screening. A case study on PPAR-alpha |
Abstract in atti di convegno pubblicato in volume |
Vai |
2016 |
MOLECULAR DYNAMICS - MULTIPLE RECEPTOR CONFORMATIONS APPROACH TO ENHANCE STRUCTURE-BASED VIRTUAL SCREENING ON PPAR-alpha RECEPTOR |
Abstract in atti di convegno pubblicato in volume |
Vai |
2016 |
A dynamic multiple receptor conformations (MD-MRC) approach to enhance early enrichment in virtual screening. A case study on PPAR-alpha |
Abstract in atti di convegno pubblicato in volume |
Vai |
2016 |
G-quadruplex vs. duplex-DNA binding of nickel(II) and zinc(II) Schiff base complexes |
Articolo in rivista |
Vai |
2015 |
Theoretical Determination of the pK a Values of Betalamic Acid Related to the Free Radical Scavenger Capacity: Comparison Between Empirical and Quantum Chemical Methods |
Articolo in rivista |
Vai |
2015 |
Studies on a new potential dopaminergic agent: in vitro BBB permeability, in vivo behavioural effects and molecular docking evaluation |
Articolo in rivista |
Vai |
2015 |
Evaluation of matrix effect on the GC/MS response of eighteen pesticides by multivariate approach |
eedings |
Vai |
2015 |
Manuale di chimica farmaceutica. Progettazione, meccanismo d'azione e metabolismo dei farmaci |
Traduzione in volume |
Vai |
2015 |
Ni(II) and Zn(II) Schiff Base complexes: B-DNA vs G4-DNA binding |
Abstract in atti di convegno pubblicato in volume |
Vai |
2015 |
Molecular modelling studies on dopamine-amino acid conjugates as potential dopaminergic modulators |
eedings |
Vai |
2015 |
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives |
Articolo in rivista |
Vai |
2015 |
Zinc complexes as fluorescent chemosensors for nucleic acids: New perspectives for a "boring" element |
Articolo in rivista |
Vai |
2015 |
Molecular modeling studies on dopamine-amino acid conjugates as potential dopaminergic modulators |
Abstract in atti di convegno pubblicato in volume |
Vai |
2015 |
Indicaxanthin from Opuntia ficus-indica Crosses the Blood−Brain Barrier and Modulates Neuronal Bioelectric Activity in Rat Hippocampus at Dietary-Consistent Amounts. |
Articolo in rivista |
Vai |
2015 |
Selective in vitro antileukemic activity (HL-60, K-562, MOLT-4, SR) of new chloro-propyl-pyrazolo[1,2-a]benzo[1,2,5]triazepinones |
Poster pubblicato in volume |
Vai |
2014 |
DNA-Binding of NiII, CuII and ZnII Complexes of Salen Derivatives |
eedings |
Vai |
2014 |
The role of side chains in Substituted Pyrrole derivatives towards antiproliferative activity |
eedings |
Vai |
2014 |
New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: Synthesis, spectroscopic studies, and biological activity |
Articolo in rivista |
Vai |
2014 |
Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation |
Articolo in rivista |
Vai |
2014 |
Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target |
Articolo in rivista |
Vai |
2014 |
Multivariate analysis in the identification of biological targets for designed molecular structures: The BIOTA protocol |
Articolo in rivista |
Vai |
2014 |
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers |
eedings |
Vai |
2014 |
Leptin and the ob-receptor as anti-obesity target: recent in silico advances in the comprehension of the protein-protein interaction and rational drug design of anti-obesity lead compounds |
Articolo in rivista |
Vai |
2014 |
The Interaction of Small Molecules with Biomolecules |
eedings |
Vai |
2014 |
Does ligand symmetry play a role in the stabilization of DNA g-quadruplex host-guest complexes? |
Articolo in rivista |
Vai |
2014 |
DA-Phen, a new dopamine aminoacid conjugate: in vivo testing and molecular modeling as dopaminergic modulator |
eedings |
Vai |
2014 |
1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions |
Articolo in rivista |
Vai |
2014 |
Selective G-Quadruplex Stabilizers: Schiff-base Metal Complexes with Anticancer Activity |
Articolo in rivista |
Vai |
2014 |
Double chained naphthalenes as G4 binders |
eedings |
Vai |
2014 |
In silico, spectroscopic, and biological insights on annelated pyrrolo[3,2-e]pyrimidines with antiproliferative activity |
Articolo in rivista |
Vai |
2014 |
A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model |
Articolo in rivista |
Vai |
2014 |
G4-DNA vs. B-DNA binding of Schiff base transition metal complexes |
eedings |
Vai |
2013 |
An Unexpected Dimroth Rearrangement Leading to Annelated Thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with Potent Antitumor Activity |
Articolo in rivista |
Vai |
2013 |
Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening |
Articolo in rivista |
Vai |
2013 |
The influence of substitution in the quinoxaline nucleus on 1,3-dipolar cycloaddition reactions |
Articolo in rivista |
Vai |
2013 |
New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol |
Articolo in rivista |
Vai |
2013 |
Hsp60, a novel target for antitumor therapy: Structure-function features and prospective drugs design |
Articolo in rivista |
Vai |
2013 |
SYNTHESIS AND EVALUATION OF CURCUMIN ANALOGUES AS NEURO-PROTECTIVE AGENTS FOR THE ALZHEIMER'S DISEASE |
eedings |
Vai |
2013 |
SELECTIVE G-QUADRUPLEX STABILIZERS: SALPHEN-LIKE COMPLEXES WITH ANTIPROLIFERATIVE ACTIVITY |
eedings |
Vai |
2013 |
Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: The effect on apoptosis induction, cell cycle and proliferation |
Articolo in rivista |
Vai |
2013 |
Design and synthesis of high affinity compounds for the Hsp60 expression
control in carcinogenic processes |
eedings |
Vai |
2013 |
Verso l’ottimizzazione dell’attività antiproliferativa di derivati pirroloisochinolinici |
eedings |
Vai |
2013 |
A3 adenosine receptor: Homology modeling and 3D-QSAR studies |
Articolo in rivista |
Vai |
2013 |
DNA-binding of nickel(II), copper(II) and zinc(II) complexes: structure-affinity relationships |
Articolo in rivista |
Vai |
2013 |
Theoretical Determination Of The pKas Of Betalamic Acid Related To The Free-Radical Scavenger Capacity: Comparison Between Semi-Empirical And Ab Initio Methods |
eedings |
Vai |
2012 |
Synthesis, characterization and DNA binding studies of potential G4 stabilizer metal complexes |
eedings |
Vai |
2012 |
NOVEL ANTAGONISTS FOR AN Hsp60-BASED ANTICANCER
CHAPERONOTHERAPY |
eedings |
Vai |
2012 |
Molecular Modelling on Leptin and the Ob Receptor as anti-obesity target |
eedings |
Vai |
2012 |
In vitro and in silico studies of polycondensed diazine systems as
anti-parasitic agents |
Articolo in rivista |
Vai |
2012 |
Antiproliferative activity of Pyrrolo[3,2-c]quinoline derivatives |
eedings |
Vai |
2012 |
Receptor-guided 3D-QSAR approach for the discovery
of c-kit tyrosine kinase inhibitors |
Articolo in rivista |
Vai |
2012 |
1,2-Dihydropyrazole[1,2-a]benzo[1,2,4]triazine-3-one: deaza analogue tricyclic scaffold with valuable antiproliferative activity |
eedings |
Vai |
2012 |
Lead optimization through VLAK protocol: New annelated pyrrolo-pyrimidine derivatives as antitumor agents |
Articolo in rivista |
Vai |
2012 |
Studio del ruolo delle mutazioni “gatekeeper” V654A e T670I di c-kit kinase nell’interazione con inibitori attraverso un approccio misto Dinamica Molecolare/Docking |
eedings |
Vai |
2012 |
Molecular Dynamics studies on Mdm2 complexes: an analysis of the inhibitor
influence |
Articolo in rivista |
Vai |
2012 |
Human chaperonin disease-causing mutations: study with a prokaryotic model. |
Poster pubblicato in volume |
Vai |
2012 |
Pharmacophore modelling as useful tool in the lead compounds identification
and optimization |
eedings |
Vai |
2012 |
DERIVATI TIENO[3,2-d]-1,2,3-TRIAZIN-4(3H)ONI ANELLATI:UNA NUOVA CLASSE DI INIBITORI DI AURORA CHINASI A |
eedings |
Vai |
2012 |
IL DNA PUÒ ANCORA ESSERE CONSIDERATO UN BERSAGLIO D’ELEZIONE PER LO SVILUPPO DI NUOVI FARMACI ANTITUMORALI? |
eedings |
Vai |
2012 |
IN THE SEARCH OF LEPTIN AGONISTS AS ANTI-OBESITY DRUGS:
PROTEIN/PROTEIN DOCKING, MOLECULAR DYNAMICS, AND
VIRTUAL SCREENING |
eedings |
Vai |
2011 |
Synthesis and antiproliferative activity of Naphtalenyl substituted 1,2-dihydropyrazol-5-one and related fused tetrazine |
eedings |
Vai |
2011 |
Virtual lock-and-key approach: The in silico revival of Fischer model by means
of molecular descriptors |
Articolo in rivista |
Vai |
2011 |
STUDIO DELL'INTERAZIONE DI DNA-NATIVO CON Zn(3-ACETIL-1-(2-NITROFENIL)PENTAN-1,4-DIONATO)2 |
eedings |
Vai |
2011 |
Study of the role of “gatekeeper” mutations V654A
and T670I of c-kit kinase in the interaction with
inhibitors by means mixed molecular
dynamics/docking approach |
Articolo in rivista |
Vai |
2011 |
Nuovi inibitori di Aurora chinasi A come target biologico coinvolto nei processi carcinogenici |
eedings |
Vai |
2011 |
A3 Adenosine Receptor: homology modeling and
3D-QSAR studies |
eedings |
Vai |
2011 |
In vitro and in silico studies of polycondensed diazine systems as anti-infective agents |
eedings |
Vai |
2010 |
The discovery of new inhibitors of HIF-1 transcriptional activity by virtual screening |
eedings |
Vai |
2010 |
3D-QSAR Pharmacophore Modeling and in Silico Screening of new Bcl-xl Inhibitors |
Articolo in rivista |
Vai |
2010 |
Design, synthesis, and biological evaluation of pyridothienotriazolopyrimidine derivatives as new HSP90 inhibitors |
eedings |
Vai |
2010 |
TECNICHE DI MODELLISTICA MOLECOLARE NELLA PROGETTAZIONE DI INIBITORI DELL'ATTIVITÀ TRASCRIZIONALE DI HIF-1 |
eedings |
Vai |
2010 |
Molecular Modeling Approaches in the Discovery of New Drugs for Anti-Cancer Therapy: The Investigation of p53-MDM2 Interaction and its Inhibition by Small Molecules |
Articolo in rivista |
Vai |
2010 |
Design of new DNA-interactive agents
by molecular docking and QSPR approach |
Articolo in rivista |
Vai |
2010 |
THE PURPOSING OF NEW COMPOUNDS OR THE RE-PURPOSING OF OLD DRUGS BY MEANS OF MULTIVARIATE ANATYSIS ON
MOLECULAR DESCRIPTORS |
eedings |
Vai |
2010 |
THE DISCOVERY OF NEW HIF-1 INHIBITORS THROUGH
MOLECULAR MODELING STUDIES |
eedings |
Vai |
2010 |
IKK-beta inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches |
Articolo in rivista |
Vai |
2010 |
Inside c-kit tyrosine kinase: molecular modeling and
QSAR in the search of new inhibitors |
eedings |
Vai |
2010 |
Study of Reactivity in the 1,3-Dipolar Cycloaddition Reactions Leading to New Triazolopyrrolopyrazine Ring Systems |
Articolo in rivista |
Vai |
2009 |
PROGETTAZIONE, SINTESI E VALUTAZIONE BIOLOGICA DI NUOVI INIBITORI DI HSP90 |
eedings |
Vai |
2009 |
A QSAR study investigating the potential anti-HIV-1 effect of some Acyclovir and Ganciclovir analogs |
Articolo in rivista |
Vai |
2009 |
Inside the Hsp90 inhibitors binding mode through induced fit docking |
Articolo in rivista |
Vai |
2009 |
Virtual lock and key approach: the revival of Fischer model |
eedings |
Vai |
2009 |
The Role of 1,3-Dipolar Cycloaddition Reactions in the Design and Synthesis of Complex Heterocyclic Scaffolds with Anti-tumor/Anti-infective Activity |
eedings |
Vai |
2009 |
Apoptotic induction on HeLa tumor cell
line. A comparison of activity between
pyrazolo[1,2-a]benzo[1,2,3,4]tetrazinone
derivatives and their synthetic precursors |
eedings |
Vai |
2009 |
Computational methodologies in the discovery of inhibitors of HIV-1 |
eedings |
Vai |
2009 |
Studi di dinamica molecolare su Mdm2 legata a due differenti inibitori |
eedings |
Vai |
2009 |
SCREENING APOPTOTICI SU NUOVI DERIVATI PIRAZOLO[1,2-A]BENZO[1,2,3,4]TETRAZINONI |
eedings |
Vai |
2009 |
Reactivity of asymmetric benzo-condensed diazines with nitrilimine dipoles in the 1,3-dipolar cycloaddition reactions |
Articolo in rivista |
Vai |
2009 |
Molecular Modeling and Dynamics of the transcriptionfactor NF-kB complexed with IkB |
eedings |
Vai |
2009 |
Targeted synthesis of pyrrolo tricycles for selective biomolecules overexpressed in cancer cells |
eedings |
Vai |
2009 |
Combined use of PCA and QSAR/QSPR to predict the drugs mechanism of action. An application to the NCI ACAM Database |
Articolo in rivista |
Vai |
2009 |
In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators |
Articolo in rivista |
Vai |
2009 |
The influence of acidic pH environment in regulating the activity of novel HIF-1 inhibitors |
eedings |
Vai |
2009 |
Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors |
Articolo in rivista |
Vai |
2008 |
Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement |
Articolo in rivista |
Vai |
2008 |
Principal Component Analysis on molecular descriptors as alternative point of view in the search of new Hsp90 inhibitors |
eedings |
Vai |
2008 |
BINDING MODES OF HSP90 INHIBITORS INVESTIGATED THROUGH INDUCED FIT DOCKING: IMPORTANCE OF ACTIVE SITE FLEXIBILITY |
eedings |
Vai |
2008 |
1,3-Dipolar cycloadditions in the synthesis of annelated diazines: design of new scaffolds for anticancer and antimicrobial agents |
eedings |
Vai |
2008 |
Study on the mechanism of action of antitumor photochemotherapic agents by means of docking and QSPR analysis |
eedings |
Vai |
2008 |
Identificazione e sintesi di nuovi potenziali inibitori di Heat Shock Protein 90 |
eedings |
Vai |
2008 |
Investigation of flap motions in wild type and M46I/G51D Mutant HIV-1 Protease by molecular dynamics studies |
eedings |
Vai |
2008 |
LOOKING FOR NEW HSP-90 INHIBITORS THROUGH A MOLECULAR DOCKING/PHARMACOPHORE APPROACH |
eedings |
Vai |
2008 |
Sintesi di Nuovi Derivati del Sistema Triciclico Pirazolo[3,4-d][1,2,3]triazolo[1,5-a]pirimidinico DNA interattivi |
eedings |
Vai |
2008 |
Pharmacophore modeling e screening in silico di nuovi inibitori della proteina antiapoptotica Bcl-xl |
eedings |
Vai |
2008 |
New imidazo[1,2-c]pyrrolo[3,2-e]pyrimidinone derivatives as potential DNA-binders |
eedings |
Vai |
2008 |
DOCKING AND MULTIVARIATE METHODS TO EXPLORE HIV-1 DRUG-RESISTANCE: A COMPARATIVE ANALYSIS |
Articolo in rivista |
Vai |
2008 |
Nuovi derivati 3,5-diaril-4,5-diidropirazolici come inibitori di HSP90 |
eedings |
Vai |
2008 |
Design and Synthesis of 4-Substituted Indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Derivatives with Antitumor Activity |
Articolo in rivista |
Vai |
2008 |
PCA and QSAR/QSPR used in combination to predict the drugs mechanism of action. An application to the NCI ACAM Database |
eedings |
Vai |
2008 |
Bis-1,2,4-triazolo[4,3-a:3',4'-c]quinoxalines of pharmaceutical interest from 1,3-dipolar cycloaddition |
Articolo in rivista |
Vai |
2008 |
MOLECULAR DYNAMICS AND DOCKING IN THE STUDY OF NEW INHIBITORS OF MDM2-p53 INTERACTION |
eedings |
Vai |
2008 |
Intercalation of daunomycin into stacked DNA base pairs. DFT study of an anticancer drug |
Articolo in rivista |
Vai |
2007 |
Benzothieno-triazolo-pyrimidine: a new class of potential DNA-binders |
eedings |
Vai |
2007 |
ISOINDOLO[2,1-C]BENZO[1,2,4]TRIAZINES: A NEW RING SYSTEM WITH ANTIPROLIFERATIVE ACTIVITY |
Articolo in rivista |
Vai |
2007 |
Reattività di diazine benzocondensate asimmetriche nelle reazioni di cicloaddizione 1,3-dipolare con dipoli nitriliminici |
eedings |
Vai |
2007 |
Molecular dynamics studies on HIV-1 protease: a comparison of the flap motions between wild type protease and the M46I/G51D double mutant |
Articolo in rivista |
Vai |
2007 |
Docking and synthesis of pyrrolopyrimidodiazepinone derivatives (PPDs) and their precursors: new scaffolds for DNA-interacting agents |
Articolo in rivista |
Vai |
2007 |
Studi spettroscopici su complessi indolotriazolopirimidina-DNA nativo. |
eedings |
Vai |
2007 |
Molecular Docking approach on the Topoisomerase I inhibitors series included in the NCI anti-cancer agents mechanism database |
Articolo in rivista |
Vai |
2007 |
Potenziali agenti DNA-interattivi: Benzotieno[2,3-e][1,2,3]triazolo[1,5-a]pirimidine |
eedings |
Vai |
2007 |
New triazolo-pyrrolopyrazine systems by 1,3-dipolar cycloaddition |
eedings |
Vai |
2007 |
Molecular modelling and QSAR in the discovery of HIV-1 integrase inhibitors |
Articolo in rivista |
Vai |
2007 |
Protocollo chemiometrico per la predizione del meccanismo di azione di derivati a potenziale attività antitumorale |
eedings |
Vai |
2007 |
Bcl-2 come target di farmaci antitumorali modulatori dell'apoptosi |
eedings |
Vai |
2007 |
Sintesi di derivati tetraidrobis-triazolochinossalinici e di nuovi sistemi triazolopirrolopirazinici di interesse biologico mediante cicloaddizioni 1,3-dipolari |
eedings |
Vai |
2007 |
Pirazolo[3,4-d][1,2,3]triazolo[1,5-a]pirimidina: accesso sintetico tramite cicloaddizioni 1,3-dipolari e riarrangiamento di Dimroth |
eedings |
Vai |
2007 |
DNA minor groove binders: an overview on molecular modeling and QSAR approaches |
Articolo in rivista |
Vai |
2006 |
NCI Anti-cancer agent mechanism database. An analysis by the combined use of molecular docking and QSPR |
eedings |
Vai |
2006 |
A convenient synthesis of cycloadduct bis-1,2,4-triazolo[4,3-a:3’,4’-c]quinoxalines by 1,3-dipolar cycloaddition |
eedings |
Vai |
2006 |
A Multivariate Analysis of HIV-1 Protease Inhibitors and Resistance Induced by Mutation |
Articolo in rivista |
Vai |
2006 |
METODI CHEMIOMETRICI NELLO STUDIO DEGLI INIBITORI DI HIV-1:
TECNICHE STATITICHE MULTIVARIATE E MOLECULAR DOCKING |
Tesi di dottorato pre 2013 |
Vai |
2006 |
MADoSPRO: a new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders |
Articolo in rivista |
Vai |
2006 |
Molecular Docking and QSPR approach on NCI Anti-Cancer Agents Mechanism Database Topoisomerase I inhibitors |
eedings |
Vai |
2006 |
Bis-1,2,4-triazolo[4,3-a:3’,4’-c]quinoxalines of pharmaceutical interest from 1,3-dipolar cycloaddition |
eedings |
Vai |
2006 |
Molecular modelling studies on new series of DNA-interactive annelated pyrrolo-pyrimidines |
eedings |
Vai |
2006 |
1,3-Dipolar cycloaddition in the synthesis of a new potential DNA-intercalating agent: indolo[3,2-e]pyrrolo[1,2-c]triazolo[1,5-a]pyrimidine |
eedings |
Vai |
2006 |
A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine |
Articolo in rivista |
Vai |
2006 |
Sintesi di derivati triazolo-chinossalinici e triazolo-pirrolopirazinici di interesse farmaceutico mediante cicloaddizioni 1,3-dipolari |
eedings |
Vai |
2006 |
A multivariate analysis on HIV-1 protease inhibitors and resistance induced by mutation |
eedings |
Vai |
2005 |
Chemometric Methods in the Study of HIV-1 Inhibitors and Resistance Induced by Mutations |
eedings |
Vai |
2005 |
2,5-bis(3'-Indolyl)thiophenes, Analogues of Marine Alkaloid Nortopsentin. |
eedings |
Vai |
2005 |
1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, Synthesis, and Biological Activity of New Antitumor Agents |
Articolo in rivista |
Vai |
2005 |
Design and Synthesis of Annelated Triazolo-pyrimidines with Antitumor Activity |
eedings |
Vai |
2005 |
SYNTHESIS AND PHOTOCHEMIOTHERAPEUTIC ACTIVITY OF THIOPYRANO[2,3-E]INDOL-2-ONES |
Articolo in rivista |
Vai |
2005 |
20Th International Congress of Heterocyclic Chemistry (20ICHC) |
Articolo in rivista |
Vai |
2005 |
In House Methodology to Assign the Mechanism of Action of New Annelated Triazolopyrimidine Derivatives with Anticancer Activity |
eedings |
Vai |
2005 |
Analisi Multivariata e Docking nello Studio degli Inibitori di HIV-1 Integrasi |
eedings |
Vai |
2005 |
HIV-1 Protease Inhibitors and Resistance Induced by Mutation. Correlation between Multivariate Analysis and Molecular Docking. |
eedings |
Vai |
2005 |
Synthesis and Antiproliferative Activity of [1,2,3,5]tetrazino[5,4-a]indoles, a New Class of Azolo-tetrazinones |
Articolo in rivista |
Vai |
2005 |
New Tricyclic System of Biological Interest Thieno[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Trough Domino Reactions of 2-Azidothiophene. |
eedings |
Vai |
2005 |
Isoindolo[1,2-a]quinoxaline derivatives with potent antitumor activity. |
eedings |
Vai |
2005 |
SYNTHESIS OF 3,5-BIS(3'-INDOLYL)PYRAZOLES, ANALOGUES OF NORTOPSENTIN |
eedings |
Vai |
2005 |
20 International Congresses of Heterocyclic Chemistry |
Altro |
Vai |
2005 |
2-OXO-[1,4]OXAZINO[3,2-E]INDOLE: A NEW RING SYSTEM WITH POTENTIAL PHOTOBIOLOGICAL PROPERTIES |
eedings |
Vai |
2005 |
Annelated Pyrrolo-pyrimidines from Amino-cyanopyrroles and BMMAs as Leads for New DNA-interactive Ring Systems |
Articolo in rivista |
Vai |
2005 |
A new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders |
Articolo in rivista |
Vai |
2004 |
European School of Medicinal Chemistry (Advanced Course of Medicinal Chemistry and National Seminar "E.Duranti" for PhD students) |
Altro |
Vai |
2004 |
Studi di Docking su Isomeri della Distamicina e della Netropsina |
eedings |
Vai |
2004 |
Synthesis and Antiproliferative Activity of [1,2,4]triazino[4,3-a]indoles |
Articolo in rivista |
Vai |
2004 |
“QSPR, Sintesi ed Attività Biologica di Nuovi Derivati del Sistema Tetraciclico Indolo[3,2-e][1,2,3]triazolo[1,5-a]pirimidinico.” |
eedings |
Vai |
2004 |
A multivariate analysis on non-nucleoside HIV-1 reverse transcriptase inhibitors and resistance induced by mutation |
Articolo in rivista |
Vai |
2004 |
Design and Synthesis of Annelated Pyrrolo-pyrimidines as Leads for New Antitumor Agents. |
eedings |
Vai |
2004 |
Sintesi ed Attivita’ Fotobiologica di Tiopirano[2,3-c]indol-2-oni |
eedings |
Vai |
2004 |
Pirrolo[3,4-h]chinolinoni: Potenziali Agenti Fotochemioterapici |
eedings |
Vai |
2004 |
Studi di Molecular Modelling su Derivati del Nuovo Sistema Eterociclico DNA-interattivo Isoindolo[2,1-c]benzo[1,2,4]triazina |
eedings |
Vai |
2004 |
Studi di Modellistica Molecolare e Sintesi di Sistemi Indolotriazolopirimidinici |
eedings |
Vai |
2004 |
Molecular Modelling Studies on New Series of DNA-Interactive annelated Pyrrolo-pyrimidines |
eedings |
Vai |
2004 |
Docking of indolo- and pyrrolo-pyrimidines to DNA. New DNA-interactive polycycles from amino-indoles/pyrroles and BMMA. |
Articolo in rivista |
Vai |
2004 |
Sintesi di Nuovi Derivati 2,5-bis(3’Indolil)tiofeni, Analoghi dell’Alcaloide Marino Nortopsentina. |
eedings |
Vai |
2004 |
Sintesi di Oligopeptidi Pirrolici Isomeri della Distamicina e della Netropsina |
eedings |
Vai |