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Factors associated with circulating concentrations of irisin in the general population cohort of the ABCD study

  • Autori: Buscemi, S; Corleo, D; Vasto, S; Buscemi, C; Massenti, M F; Nuzzo, D; Lucisano, G; Barile, A M; Rosafio, G; Maniaci, V; Giordano, C
  • Anno di pubblicazione: 2017
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link:


Animal studies have shown that irisin is a myokine secreted following physical exercise, and that it induces the remodeling of white adipose tissue toward brown adipose tissue. Therefore, a protective role of irisin against obesity, diabetes, and other metabolic and cardiovascular conditions has been hypothesized. However, data in humans are contradictory and few data are available concerning the general population.