Acetic acid and acidification accelerate chronological and replicative aging in yeast

Abstract

yeast is widely regarded as one of the most valuable model systems to study aging and particularly the genetics of aging. Researchers have established two different methods to study yeast aging known as the replicative lifespan (RLS) and the chronological lifes- pan (CLS). These have led to the identifica- tion of many mammalian genes that affect aging suggesting that they will continue to shed light on the fundamental biology of aging.