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GAETANO GIAMMONA

Radiation synthesis of polyaspartamide functionalised hydrogels for sustained release of fragrances

  • Autori: Dispenza, C.; Battaglia, G.; Giammona, G.; Licciardi, M.; Spadaro, G.
  • Anno di pubblicazione: 2005
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: ORAL PROTEIN DELIVERY
  • OA Link: http://hdl.handle.net/10447/5478

Abstract

The aim of the present investigation is to assess the possibility of obtaining a biocompatible material device which is able to deliver oil-soluble fragrances in air over a length of time. Aqueous solutions of polyaspartamide functionalised with glycidyl methacrylate have been cross linked through gamma irradiation in the presence of a lipophilic model fragrance, emulsified prior to irradiation. Two emulsification conditions have been considered at two different concentrations of both fragrance and surfactant in water. Chemical hydrogels have been obtained in correspondence to two irradiation absorbed doses and have been characterised for their solubility properties and swelling ability in water. Both static and dynamic release experiments of the fragrance in air have been performed and the release behaviour related to the hydrogel network structure and its water retention properties.