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ANTONINO BIANCO

INFLUENCE OF FAMILY HISTORY OF TYPE 2 DIABETES ON PHENOTYPE AND PERFORMANCE IN YOUNG PEOPLE OF BOTH SEX.

  • Autori: Bianco, A.; Pomara, F.; Basile, D.; Petrucci, M.; Battaglia, G.; Paoli, A.; Bellafiore, M.; Palma, A.
  • Anno di pubblicazione: 2010
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: type 2 diabetes – family history – phenotype – adolescent
  • OA Link: http://hdl.handle.net/10447/49808

Abstract

The type 2 diabetes is commonly considered a complex genetic disease, resulting from interactions between multiple genes and environmental factors without any single factor having strong independent effects. We studied the influence of family history to type 2 diabetes on physical phenotype of 47 health adolescents. In both sexes groups with positive family history (FH+) had the highest values of stature and body weight (p<0.05 for males, not significant for females), waist circumference (p<0.05 for males, not significant for females), and wrist circumference (p=0.05 for males, not significant for females). Considering performance, FH+ males showed a significant higher performance in power exercises than FH- males; no significant differences were found between FH+ and FH- female groups. Family history to type 2 diabetes can induce in both sexes precocious phenotype and performances linked-related variations; more studies are necessary to confirm these data and to verify preventive interventions promoting significant life-style changes.