Maxillary bone necrosis following the use of bisphosphonates in patients with cancer: management and case series
- Authors: TORTORICI S; BURRUANO F; CARADONNA L; BUZZANCA ML AND DIFALCO P
- Publication year: 2008
- Type: Articolo in rivista
- Key words: Bisphosphonates, bone necrosis, avascular necrosis of the jaw, cancer, case series
- OA Link: http://hdl.handle.net/10447/14408
Abstract
Bisphosphonates are bone-turnover modulating drugs used to treat various diseases such as certain cancers, bone metastasis, bone- and calcium-related disorders, Paget`s disease, osteoporosis and osteopenia. Recently, several preliminary reports have reported the insurgence of osteonecrosis of the mandible and/or maxilla, associated with intravenously administered bisphosphonates. This case series describes the effects of bisphosphonates used in the treatment of certain cancers on oral bone tissues.