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LAURA TOMASELLO

Donor age and long-term culture do not negatively influence the stem potential of limbal fibroblast-like stem cells

  • Autori: Tomasello, L.; Musso, R.; Cillino, G.; Pitrone, M.; Pizzolanti, G.; Coppola, A.; Arancio, W.; DI CARA, G.; Pucci Minafra, I.; Cillino, S.; Giordano, C.
  • Anno di pubblicazione: 2016
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/179190

Abstract

In regenerative medicine the maintenance of stem cell properties is of crucial importance. Ageing is considered a cause of reduced stemness capability. The limbus is a stem niche of easy access and harbors two stem cell populations: epithelial stem cells and fibroblast-like stem cells. Our aim was to investigate whether donor age and/or long-term culture have any influence on stem cell marker expression and the profiles in the fibroblast-like stem cell population.