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Quality of life in patients with bladder cancer undergoing ileal conduit: A comparison of women versus men

  • Autori: Siracusano, S.; D’Elia, C.; Cerruto, M.; Saleh, O.; Serni, S.; Gacci, M.; Ciciliato, S.; Simonato, A.; Porcaro, A.; De Marco, V.; Talamini, R.; Toffoli, L.; Visalli, F.; Niero, M.; Lonardi, C.; Imbimbo, C.; Verze, P.; Mirone, V.; Racioppi, M.; Iafrate, M.; Cacciamani, G.; De Marchi, D.; Bassi, P.; Artibani, W.
  • Anno di pubblicazione: 2018
  • Tipologia: Articolo in rivista (Articolo in rivista)
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Background/Aim: Studies comparing health-related quality of life (HR-QoL) between patients who underwent radical cystectomy (RC) and those who underwent a different form of urinary diversion has not reached yet univocal and reliable conclusions. The aim of our study was to evaluate bladder-specific long-term HR-QoL after radical cystectomy and ileal conduit. Patients and Methods: A multicenter study was carried out on 145 consecutive patients (112 males and 33 females) undergoing RC and ileal conduit (IC). HR-QoL assessment was conducted using Italian versions of European Organisation for Research and Treatment of Cancer QLQ-C30 and EORTC BLM-30 questionnaires. Results: Our data showed that women who underwent IC presented greater problems than men in cognitive functioning (mean score±SD: 77.3±27.9 vs. 87.8±18.6) as well in future perspective (score: 42.4±34.4 vs. 21.9±24.6). Nevertheless, men undergoing IC had more problems in sexual functioning than women (score: 23.3±24.5 vs. 7.0±20.3) (all p<0.05). Conclusion: In our series, female patients presented a greater burden than male patients in cognitive functioning as well in future perspective, but lower concerns with regard to sexual function.