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Biological activities of the extracts from macroalgae Carpodesmia crinita, Carpodesmia brachycarpa, Asparagopsis taxiformis

  • Autori: Badalamenti Rosario ,Palumbo Piccionello A.,Settanni Luca, Mauro Manuela, Vazzana Mirella ,Attanzio Alessandro,Restivo Ignazio,Vizzini Aiti,Arizza Vincenzo
  • Anno di pubblicazione: 2023
  • Tipologia: Abstract in atti di convegno pubblicato in volume
  • OA Link:


Marine species represent a rich source of biologically active products that can be used in various fields. Among them, marine algae produce numerous secondary metabolites responsible for different biological activities such as: immunomodulatory [1], antioxidant [2], and antimicrobial [3]. The aim of this study was chemically characterizing the extracts of three macroalgae species: Carpodesmia crinite (Duby) Orellana & Sansón, 2019, Carpodesmia brachycarpa (J. Agardh) Orellana & Sansón 2019, Asparagopsis taxiformis (Delile) Trevisan 1845 and evaluate their biological activities. The characterization of the secondary metabolites was performed by HPLC-MS and the results obtained showed higher meroterpenoids levels. Moreover, the extracts tested against the Arbacia lixula sea urchin modulate the total and differential cellular count demonstrating their involvement in immunity responses. Furthermore, important antimicrobial activities were observed by testing these extracts against the bacterial strains Listeria monocytogenes and Staphylococcus aureus. For the first time our study shows the effects of macroalgae extracts on the immunomodulatory activity in Arbacia lixula sea urchin and important antimicrobial activity. The results obtained, although preliminary, are certainly encouraging and our purpose is also improved this information performing biochemical and molecular assays of extracts obtained to understand better the potential that these metabolites have towards the sea urchin Arbacia lixula that graze on these macroalga.