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MANUELA LABBOZZETTA

Pubblicazioni

Data Titolo Tipologia Scheda
2020 Can NF-κB Be Considered a Valid Drug Target in Neoplastic Diseases? Our Point of View Review essay (rassegna critica) Vai
2019 Synthesis of Curcumin Derivatives and Analysis of Their Antitumor Effects in Triple Negative Breast Cancer (TNBC) Cell Lines Articolo in rivista Vai
2019 Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvement Articolo in rivista Vai
2019 Essential Oil Composition of Alluaudia procera and in Vitro Biological Activity on Two Drug-Resistant Models Articolo in rivista Vai
2019 Antitumor mechanism of the essential oils from two succulent plants in multidrug resistance leukemia cell Articolo in rivista Vai
2019 Essential oil of Cyphostemma juttae (Vitaceae): chemical composition and antitumor mechanism in triple negative breast cancer cells Articolo in rivista Vai
2018 Chemical Composition, In Vitro Antitumor and Pro-Oxidant Activities of Glandora rosmarinifolia (Boraginaceae) Essential Oil Articolo in rivista Vai
2018 MDA-9/Syntenin-NF-κB-RKIP loop in triple negative breast cancers (TNBC) and human liver carcinoma Proceedings (TIPOLOGIA NON ATTIVA) Vai
2018 Potential Therapeutic Applications of MDA-9/Syntenin-NF-κB-RKIP Loop in Human Liver Carcinoma Articolo in rivista Vai
2017 NF-kB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers Articolo in rivista Vai
2016 Chemical and pharmaceutical evaluation of the relationship between triazole linkers and pore size on cyclodextrin–calixarene nanosponges used as carriers for natural drugs Articolo in rivista Vai
2015 NF-κB is a potential pharmacological target in triple negative breast cancers. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 Rash and multiorgan dysfunction following lamotrigine: could genetic be involved? Articolo in rivista Vai
2015 Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple‑negative breast cancer SUM 159 cells Articolo in rivista Vai
2014 Mechanisms of Raf-1 Kinase Inhibitor Protein Dysregulation in Triple-Negative Breast Cancers and Identification of Possible Novel Therapeutic Approaches for These Tumors Articolo in rivista Vai
2013 Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients Articolo in rivista Vai
2013 Analysis of pharmacologic approaches able to restore RKIP function in hepatocellular carcinoma Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Analysis of UGT1A1*28 and DPYD*2A polymorphisms in Sicilians patients with metastatic colorectal cancer treated with Irinotecan and 5-fluorouracil. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Expression of a specific Thymidylate synthase polimorfic allele in metastatic colorectal patients is regulated by Myeloid Zinc Finger 1. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Unusual high dose of tacrolimus in liver transplant patient, a case report. Articolo in rivista Vai
2012 ANALISI DEI POLIMORFISMI DEI GENI CODIFICANTI PER L'ENZIMA UDP-GLUCURONILTRANSFERASI (UGT) E PER L'ENZIMA DIIDROPIRIMIDINA DEIDROGENASI (DPD), CORRELATI A MAGGIORE TOSSICITA' IN SEGUITO A TRATTAMENTO, RISPETTIVAMENTE, CON IRINOTECANO E CON 5-FLUOROURACILE IN SOGGETTI CON TUMORE COLON RETTALE (CRC). Tesi di dottorato pre 2013 Vai
2012 Alteration of signaling pathways in hepatocellular carcinoma: identification of new pharmacological targets and possible prognosis markers. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma: investigation of possible mechanisms Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Analysis of Possible Mechanisms Accounting for Raf-1 Kinase Inhibitor Protein Downregulation in Hepatocellular Carcinoma Articolo in rivista Vai
2012 Design and synthesis of hybrid drugs based on curcumin scaffold Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Analisi dei polimorfismi dei geni codificanti per l’enzima UDP-glucuronosiltrasferasi (UGT) e per l’enzima diidropirimidina deidrogenasi (DPD), correlati a maggiore tossicità in seguito a trattamento, rispettivamente, con Irinotecano e con 5-Fluorouracile in soggetti con tumore colon rettale (CRC) Tesi di dottorato pre 2013 Vai
2011 Possible mechanisms of Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma Proceedings (TIPOLOGIA NON ATTIVA) Vai
2011 Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients. Articolo in rivista Vai
2011 Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels Articolo in rivista Vai
2011 Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma Articolo in rivista Vai
2011 Restoration of Raf-1 Kinase Inhibitor Protein levels as a possible therapeutic approach in hepatocellular carcinoma. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2010 Yin Yang 1 and Raf-1 Kinase Inhibitory Protein Status in Hepatocellular Carcinoma: Future Perspectives Articolo in rivista Vai
2010 Frequent alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein ratio in hepatocellular carcinoma Proceedings (TIPOLOGIA NON ATTIVA) Vai
2010 Altered Yin Yang 1/RAF-1 kinase inhibitory protein ratio as a possible molecular marker and therapeutic target in hepatocellular carcinoma Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities. Articolo in rivista Vai
2009 ELABORATION OF CURCUMIN INTO DIKETONE MODIFIED ANALOGUES DEVOID OF NUCLEOPHILIC ADDITION CAPABILITY; IMPLICATIONS FOR THEIR ANTITUMOR AND CHEMOSENSITIZING ACTIVITIES Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Potential role of the natural multi-targeted agent curcumin in the treatment of oral diseases. Articolo in rivista Vai
2009 Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer Articolo in rivista Vai
2009 The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients Articolo in rivista Vai
2008 Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells Articolo in rivista Vai
2008 Plant polyphenols as possible lead compound against hormone-independent multidrug resistant breast cancer. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2008 THE EFFECT OF CYP3A5 AND ABCB1 SINGLE NUCLEOTIDE POLYMORPHISMS ON TACROLIMUS DOSE REQUIREMENTS IN CAUCASIAN LIVER TRANSPLANT PATIENTS Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 Pro-oxidant and antitumor effects of curcumin and N-ethylmaleimide in the HA22T/VGH model Overt hepatocellular carcinoma. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 The antitumor activities of curcumin and its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 brest cancer cell line: Analysis of the possible molecular basis. Articolo in rivista Vai
2007 Effetti della curcumina e di suoi analoghi modificati al frammento beta-dichetone in cellule tumorali multifarmacoresistenti. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 DISTRIBUTION OF CYP3A5 AND MDR-1 SINGLE NUCLEOTIDE POLYMORPHISMS IN CAUCASIAN LIVER TRANSPLANT PATIENTS Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 The antitumor activities of curcumin and of its novel isoxazole analogue MR 39 are not hampered by the multidrug resistant condition of tumor cells expressing both P-glycoprotein and different inhibitory of apoptosis proteins Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 The NF-kB inhibitors curcumin and DHMEQ exert antitumor synergy with cisplatin in hepatic cancer cells. Analysis of relationship to IL-6 production. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Le attività antitumorali della curcumina e del suo più potente analogo isossazolico non sono compromesse dal pattern di espressione genica della variante MDR della linea di carcinoma mammario MCF-7 Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 “Antitumor and molecular effects of curcumin and of its isoxazole analogue on multidrug resistant breast cancer cells. New perspectives in tumor theraphy: molecular aspects, 2006”. Capitolo o Saggio Vai
2006 "Antitumor effects of the novel NF-kB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production”. Articolo in rivista Vai
2006 Effetti della curcumina e del suo derivato isossazolico in modelli di neoplasia multifarmacoresistente Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Effects of curcumin and related analogues on tumor cell lines expressing multiple mechanisms of drug resistance Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma Articolo in rivista Vai
2006 Effects of the dietary polyphenols resveratrol and curcumin on the prevention and treatment of cancer. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Significance of autologous interleukin 6 production in the HA22T/VGH model of hepatocellular carcinoma Articolo in rivista Vai
2005 Antitumor effects of curcumin, alone or in combination with cisplatin, on hepatic cancer cells. Analysis of their relationship to IL-6 production Proceedings (TIPOLOGIA NON ATTIVA) Vai
2005 Antitumor effects of the NF-kB inhibitors curcumin and DHMEQ, alone or combined with cisplatin, on hepatic cancer cells. analysis of their relationship to IL-6 production. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2005 Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possibile relationship to the effects on inhibitor of apoptosis protein levels Articolo in rivista Vai
2005 Antitumor effects of curcumin in human hepatic cancer cells: Analysis of their relationship to inhibition of NF-kB and pro-survival gene expression. Altro Vai
2005 New trends in overcoming drug resistance in hepatocellular carcinoma. Looking for pharmacological inhibition of Inhibitory of Apoptosis Proteins (IAPs) by curcumin. Capitolo o Saggio Vai
2005 Antitumor effects of the grape stilbenes resveratrol and piceatannol on multidrug and apoptosis resistant HL60 leukemia cells" Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Evaluation of patients with thrombotic stroke by methionine loading oral curve Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Curva da carico orale di metionina nella valutazione di pazienti affetti da patologia trombotica Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells Articolo in rivista Vai
2004 Plasma omocysteine levels in patients with chronic renal failure Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Plasma homocysteine levels in patients with chronic renal failure Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Evaluations and new relationships between renal failure and homocysteine plasma levels in patients with chronic renal failure Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Evaluations and new relationship between renal failure and homocysteine plasma levels in patients with chronic renal failure. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation Articolo in rivista Vai
2004 Plasma homocysteine levels in patients with chronic renal failure. Proceedings (TIPOLOGIA NON ATTIVA) Vai