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MICHELA GIULIANO

Curriculum e ricerca

Insegnamenti

Anno accademico Codice della materia Nome della materia CFU Corso di studi
2020/2021 08559 BIOCHIMICA 6 INGEGNERIA CHIMICA E BIOCHIMICA
2020/2021 18658 BIOCHIMICA ANALITICA (MODULO) 3 SCIENZE BIOLOGICHE
2020/2021 01560 BIOCHIMICA CON ESERCITAZIONI 9 SCIENZE BIOLOGICHE
2020/2021 18661 BIOCHIMICA PER IL LABORATORIO BIOMEDICO 6 SCIENZE BIOLOGICHE
2020/2021 15559 MECCANISMI BIOCHIMICI DELLE FUNZIONI CELLULARI 6 BIOLOGIA MOLECOLARE E DELLA SALUTE

Pubblicazioni

Data Titolo Tipologia Scheda
2020 Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to biochemical effects Articolo in rivista Vai
2019 Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway Articolo in rivista Vai
2019 The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells Articolo in rivista Vai
2019 WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner Articolo in rivista Vai
2018 Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review Articolo in rivista Vai
2018 The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer Articolo in rivista Vai
2018 Ethanol promotes survival and tumor progression of colon cancer cells Contributo in atti di convegno pubblicato in volume Vai
2018 Sicilian litchi fruit extracts induce autophagy versus apoptosis switch in human colon cancer cells Articolo in rivista Vai
2018 Let-7d-5p miRNA shows oncogenic functions in triple negative breast cancer Proceedings (TIPOLOGIA NON ATTIVA) Vai
2017 Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways. Articolo in rivista Vai
2017 Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas Articolo in rivista Vai
2016 Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2016 The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms. Articolo in rivista Vai
2016 DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives Articolo in rivista Vai
2016 The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells Articolo in rivista Vai
2015 ER+-derived breast cancer stem cells reveal a high expression of the serpin protease inhibitor PI-9. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 Possible regulatory mechanisms responsible for the high expression of serpin protease inhibitor PI-9 in ER+ -derived breast cancer stem cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 Different modulatory effect of the synthetic cannabinoid WIN55,212-2 on tumor cell migration. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 WIN-induced vesiculation cooperates to the inhibition of osteosarcoma cell migration Proceedings (TIPOLOGIA NON ATTIVA) Vai
2015 Il sostegno e il miglioramento delle coltivazioni sub-tropicali in Sicilia traggono vantaggio dallo studio e dalla promozione delle loro proprietà nutrizionali. Contributo in atti di convegno pubblicato in volume Vai
2014 MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells Articolo in rivista Vai
2014 WIN modulates osteosarcoma MG63 cell migration by inhibiting MMPs activity and adjusting intra- and extra-cellular SPARC differential expression Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells. Articolo in rivista Vai
2014 Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis Articolo in rivista Vai
2014 Role of sparc and MIR-29B1 in molecular effects induced by win in osteosarcoma MG63 cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2014 WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARγ down-regulation Articolo in rivista Vai
2013 Synthesis, chemical characterization and biological activity of new histone acetylation/deacetylation specific inhibitors: A novel and potential approach to cancer therapy. Articolo in rivista Vai
2013 In human retinoblastoma Y79 cells okadaic acid–parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player. Articolo in rivista Vai
2013 Genetic and molecular characterization of the human osteosarcoma 3AB-OS cancer stem cell line: a possible model for studying osteosarcoma origin and stemness. Articolo in rivista Vai
2013 Okadaic acid-Parthenolide combination at subtoxic doses induces potent synergistic apoptotic effects in human retinoblastoma Y79 cells by upregulating PTEN. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2013 Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells. Articolo in rivista Vai
2013 Studio dell'autofagia nella citotossicità indotta dai cannabinoidi in cellule tumorali Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 INVOLVEMENT OF ER-STRESS IN SPARC UP-REGULATION INDUCED BY WIN AND IN APOPTOSIS OF MG63 CELLS Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Autophagy and ER-stress participate to cannabinoid-induced apoptosis in colon carcinoma cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Cannabinoid-associated cell death mechanisms in tumor models (review) Articolo in rivista Vai
2012 Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion. Articolo in rivista Vai
2012 A comparison between the role of SPARC in osteogenic differentiation of mesenchymal stem cells and in WIN/TRAIL-induced apoptosis in osteosarcoma cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Organotin(IV) and simple fatty acids: preliminary assessments Proceedings (TIPOLOGIA NON ATTIVA) Vai
2012 Different expression of PPARs in WIN-treated cells: the game of roles Proceedings (TIPOLOGIA NON ATTIVA) Vai
2011 New histone acetylation/deacetylation specific inhibitors: a novel and potential approach to cancer therapy Proceedings (TIPOLOGIA NON ATTIVA) Vai
2010 Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt. Articolo in rivista Vai
2010 The synthetic cannabinoid WIN sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by activating p8/CHOP/DR5 axis. Articolo in rivista Vai
2010 p8 (candidate of metasiasis 1) drives ER-stress/autophagy/apoptosis axis induced by the synthetic cannabinoid WIN in HCC cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2010 Diorganotin(IV) N-acetyl-L-cysteinate complexes: Synthesis, solid state, solution phase, DFT and biological investigations. Articolo in rivista Vai
2010 USO TERAPEUTICO COMBINATO DI ORGANOSTAGNO(IV) ED INIBITORI DELLE DEACETILASI ISTONICHE Brevetto Vai
2009 The transcription factor CHOP is critical for WIN-mediated DR5 up-regulation in apoptosis induced by WIN/TRAIL co-treatment in hepatoma cells Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma. Articolo in rivista Vai
2009 COINVOLGIMENTO DELLO STRESS DEL RETICOLO E DEL PROCESSO AUTOFAGICO NELL’APOPTOSI INDOTTA DAL CANNABINOIDE SINTETICO WIN IN CELLULE DI EPATOMA UMANO IN COLTURA Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 The cannabinoid WIN induces DR5 receptor expression in hepatoma cells sensitizing them to TRAIL signal Proceedings (TIPOLOGIA NON ATTIVA) Vai
2009 Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. Articolo in rivista Vai
2008 The role of oxidative stress in apoptosis induced by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in human colon adenocarcinoma HT-29 cells. Articolo in rivista Vai
2008 ORGANOSTAGNO(IV) COMPLESSI CON N-ACETILCISTEINA AD ATTIVITÀ ANTITUMORALE, PROCEDIMENTO PER LA LORO PRODUZIONE E LORO USO. Brevetto Vai
2008 Synergistic effects induced by combinations of the synthetic cannabinoid WIN55,212-2 and the death receptor ligand TRAIL in hepatoma HepG2 cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2008 TWO-DIMENSIONAL ANALYSIS OF PROTEIN EXPRESSION PATTERNS Monografia Vai
2008 Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1. Articolo in rivista Vai
2008 CELL CULTURES Monografia Vai
2007 Hsp72 controls bortezomib-induced HepG2 cell death via interaction with pro-apoptotic factors. Articolo in rivista Vai
2007 Role of PPARγ in apoptosis induced by cannabinoids in hepatoma HepG2 cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 WIN55,212-2, a synthetic agonist of cannabinoid receptors, sensitizes tumor cells to TRAIL-induced apoptosis. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2007 Poly(ADP-ribose) polymerase (PARP): The advantages of using PARP inhibitors to modulate its activity in pathological conditions and to kill cancer cells Monografia Vai
2007 The cannabinoid system and its potential therapeutic applications in cancer. Monografia Vai
2006 Synthesis, structural investigation and biological activity of metal ions complexes of N-acetylcysteine and carbocysteine Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Factors that protect HepG2 cells by anandamide-induced cell death Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 THE CANNABINOID AGONIST WIN55,212-2 INDUCES APOPTOSIS IN HUMAN HEPATOMA CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Apoptosis induced by the histone deacetylase inhibitor SAHA in human colon adenocarcinoma cell line HT29 Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Complessi di nuova sintesi di derivati della cisteina con ioni metallici Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. Articolo in rivista Vai
2006 Hsp72 and NF-κB protect human hepatoma HepG2 cells in the first phase of treatment with bortezomib Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Hsp-72 contrasta l'effetto apoptotico indotto dal bortezomib in cellule di epatoblastoma umano Hep-G2 Proceedings (TIPOLOGIA NON ATTIVA) Vai
2006 Bortezomib induces in HepG2 cells IkappaBalpha degradation mediated by caspase-8. Articolo in rivista Vai
2005 SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2005 APOPTOTIC EFFECTS INDUCED BY ANANDAMIDE IN HEPATIC CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL. Articolo in rivista Vai
2004 The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2004 Degradation of IkBalfa during apoptosis induced by proteasome inhibitors in hepatoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Vai
2003 Apoptosis meets proteasome, an invaluable therapeutic target of anticancer drugs Articolo in rivista Vai
2003 Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb Articolo in rivista Vai
2003 The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells Articolo in rivista Vai
2003 Macrophage-mediated clearance of cells undergoing caspase-3-independent death Articolo in rivista Vai
2002 Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-Xs and activation of caspase-3 Articolo in rivista Vai
2001 pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. Articolo in rivista Vai
2001 Sodium phenylbutyrate induces apoptosis in human retinoblastoma Y79 cells: The effect of combined treatment with the topoisomerase I-inhibitor topotecan Articolo in rivista Vai
2000 Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress Articolo in rivista Vai
2000 Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells Articolo in rivista Vai
1999 The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells Articolo in rivista Vai
1998 Increased cyclin E level in retinoblastoma cells during programmed cell death Articolo in rivista Vai
1998 The apoptotic effects of cisplatin and carboplatin in retinoblastoma Y79 cells Articolo in rivista Vai
1998 Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide Articolo in rivista Vai
1998 Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors Articolo in rivista Vai
1998 Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells Articolo in rivista Vai
1997 Differentiation of Y79 cells induced by prolonged exposure to insulin Articolo in rivista Vai
1996 Role of insulin-like growth factors in autocrine growth of human retinoblastoma Y79 cells Articolo in rivista Vai
1994 Synthesis of insulin and its effects in Y79 human retinoblastoma cells Articolo in rivista Vai
1994 High-performance liquid chromatographic method for the determination of insulin synthesis in biological systems Articolo in rivista Vai
1994 Insulin synthesis in chick embryo retinas during development Articolo in rivista Vai
1992 A factor derived from chick embryo retina which inhibits DNA synthesis of retina itself Articolo in rivista Vai
1992 Identification of insulin in chick embryo retina during development and its inhibitory effect on DNA synthesis Articolo in rivista Vai
1992 Identification and synthesis of insulin in human retinoblastoma Y-79 cells Articolo in rivista Vai
1990 Effects of dexamethasone on human synovial fibroblast-like cells, from osteoarthritic joints, in culture Articolo in rivista Vai
1990 The effects of dexamethasone on human synovial fibroblast-like cells, from ostheoarthritic joints, in culture Articolo in rivista Vai
1989 Inhibition of DNA synthesis in chick embryo retinas, in vitro, by a factor from fetal bovine serum Articolo in rivista Vai
1988 Morphological and biochemical effects of glucocorticoids in chick embryo hepatocytes during development Articolo in rivista Vai
1987 Ornithine decarboxylase activity during chick embryo retina development:hydrocortisone effect Articolo in rivista Vai
1987 Influence of hydrocortisone on chick embryo retina development Articolo in rivista Vai
1987 DNA content and thymidine incorporation during chick embryo retina development:hydrocortisone effect Articolo in rivista Vai
1985 Inhibitory effect of hydrocortisone administered in ovo on thymidine kinase in chick embryo retina during development Articolo in rivista Vai
1985 Growth-inhibitory response elicited by hydrocortisone in chick embryo hepatocytes Articolo in rivista Vai
1985 Nucleoside phosphotransferase in animal tissues. Tissue distribution and kinetic properties Articolo in rivista Vai
1984 The effects of glucocorticoids on thymidine kinase and nucleoside phosphotransferase during development of chicken embryo retina Articolo in rivista Vai
1984 The purification and properties of nucleoside phosphotransferase from mucosa of chicken intestine Articolo in rivista Vai
1984 Nucleoside phosphotransferase in animal tissues Articolo in rivista Vai
1984 The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells Articolo in rivista Vai
1983 Regulatory properties of nucleoside phosphotransferase from mucosa of chicken intestine Articolo in rivista Vai
1983 The effects of glucocorticoids on thymidine kinase and nucleoside phosphotransferase during development of chicken embryo retina Articolo in rivista Vai
1983 Purification of nucleoside phosphotransferase from mucosa of chicken intestine Articolo in rivista Vai
1983 Inhibitory effect of phosphate on nucleoside phosphotransferase from chicken intestinal mucosa Articolo in rivista Vai