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SIMONA DE GRAZIA

Genetic heterogeneity and recombination in human type 2 astroviruses

  • Autori: DE GRAZIA, S.; Medici, M.; Pinto, P.; Moschidou, P.; Tummolo, F.; Calderaro, A.; Bonura, F.; Banyai, K.; Giammanco, G.; Martella, V.
  • Anno di pubblicazione: 2012
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/77925

Abstract

Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3= end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.