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PATRIZIA DIANA

Synthesis of the New Ring System 2-Oxo-[1,4]oxazino[3,2-e]indole, Heteroanalogue of Angelicin

  • Autori: Barraja, P.; Diana, P.; Montalbano, A.; Martorana, A.; Carbone, A.; Cirrincione, G.
  • Anno di pubblicazione: 2009
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: 1,4-Oxazinoindoles; 1,4-Benzoxazines; Angelicin heteroanalogue; 4-Amino-5-hydroxy indoles
  • OA Link: http://hdl.handle.net/10447/43884

Abstract

A series of 2-oxo-[1,4]oxazino[3,2-e ]indoles, heteroanalogues of Angelicin, have been synthesized by a multistep sequence consisting of the annelation of the oxazine ring on the indole moiety. The phototoxicity and the antiproliferative activity of the new derivatives were investigated.