Salta al contenuto principale
Passa alla visualizzazione normale.


Data comparison between pharmacological induction of labour and spontaneous delivery. A single centre experience

  • Autori: Granese, R.; Calagna, G.; Sollano, A.; Mondello, S.; Sicilia, A.; Grasso, R.; Cucinella, G.; Triolo, O.
  • Anno di pubblicazione: 2016
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: Induction of labour; Neonatal outcome; Prostaglandin E2; Spontaneous labour;
  • OA Link:


Objectives: To assess the differences in the maternal and fetal outcomes between pharmacological induced and spontaneous labour in nulliparous women.Material and methods: Observational cohort study carried out over a period of 2 years. Inclusion criteria: nulliparous singleton pregnancies, with cephalic fetal presentation, elective labour induction with intra-vaginal prostaglandin E2 (PGE2) gel (Prepidil® 2 mg) at a gestational age of 41 weeks. Control group: patients who entered labour spontaneously at a gestational age of ≥ 40 weeks. The main demographic maternal characteristics and intra- and postpartum data were extracted from computer records and obstetrics diaries and were used for the analysis.Results: One hundred and three patients with induction of labour and 97 with spontaneous labour were enrolled. Cesarean delivery was performed in 18 cases (17.5%), all in the induction group. There were no differences in newborn weights between the 2 groups while both the 1-minute and 5-minute Apgar scores were significantly higher in the spontaneous group (p = 0.014 and p = 0.0003, respectively). Women in the induction group had a significantly longer duration of I stage labour in comparison with spontaneous group (p < 0.0001). Conclusions: Primiparous women whose labour was induced spent a longer time in labour than women who presented in spontaneous labour. Clinicians should keep in mind that a slow rate of dilation in a woman being induced may be normal. For this reason, an arrest diagnosis needs to be carefully considered.