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ANTONIO CASCIO

Antimicrobial consumption and antimicrobial resistance: A snapshot of an Italian neuromuscular rehabilitation center

  • Autori: Barberi, G.; De Cola, M.; Dell'Utri, P.; Melardi, S.; Alagna, B.; Bramanti, P.; Cascio, A.
  • Anno di pubblicazione: 2017
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/290589

Abstract

The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-Annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam-resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).