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The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update

  • Autori: Carlo, C.; Armin, A.; Christian, B.; Bruno, B.; Gerd, B.; Carroccio, A.; Gemma, C.; Laura De Magistris, ; Walburga, D.; DI LIBERTO, D.; Luca, E.; Alessio, F.; Marios, H.; Matthew, K.; Elena, L.; Mulder, C.; Kamran, R.; Anna, S.; Katharina, S.; Detlef, S.; Nick, T.; Umberto, V.; Victor, Z.; Yurdagül, Z.; Sanders, D.
  • Anno di pubblicazione: 2017
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link:


Gluten-related disorders have recently been reclassified with an emerging scientific literature supporting the concept of non-celiac gluten sensitivity (NCGS). New research has specifically addressed prevalence, immune mechanisms, the recognition of non-immunoglobulin E (non-IgE) wheat allergy and overlap of NCGS with irritable bowel syndrome (IBS)-type symptoms. This review article will provide clinicians with an update that directly impacts on the management of a subgroup of their IBS patients whose symptoms are triggered by wheat ingestion.