Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis
- Autori: Colucci, Rocchina; Fornai, Matteo; Antonioli, Luca; Segnani, Cristina; Ippolito, Chiara; Pellegrini, Carolina; Nericcio, Anna; Zizzo, Maria Grazia; Serio, Rosa; Blandizzi, Corrado; Bernardini, Nunzia
- Anno di pubblicazione: 2022
- Tipologia: Articolo in rivista
- Parole Chiave: Cyclooxygenase; SMAD; TGF-β; fibrosis; inflammatory bowel disease
- OA Link: http://hdl.handle.net/10447/576428
Abstract
Gut fibrosis occurs under chronic inflammation. This study examined the effects of different cyclooxygenase (COX) inhibitors on fibrosis in the inflamed colon.