S-100 calcium binding proteins as potential markers for breast cancer metastasis.
- Autori: PUCCI, I;CANCEMI, P; DI CARA, G; ALBANESE, NN; MARABETI, MR; COSTANTINI, F; MUSSO, R; TAORMINA, P; MARRAZZO, A; MINAFRA, A
- Anno di pubblicazione: 2009
- Tipologia: eedings
- Parole Chiave: S-100 proteins, breast cancer
- OA Link: http://hdl.handle.net/10447/35696
Abstract
The S-100 family of calcium-binding proteins includes about 20 members of low molecular weight characterized by two consecutive EF hands domains. They make interactions with cellular target proteins in a calcium-dependent manner; therefore they are thought to regulate a variety of physiological functions, such as cell proliferation, signal transduction, cell adhesion, motility as well as cancer metastasis.