Thrombocytopenia and hyperinflammation are induced by extracellular histones circulating in blood
- Autori: Giglio, R.V.; Ligi, D.; Della Franca, C.; Lo Sasso, B.; Rivas, J.Z.; Agnello, L.; Mannello, F.; Ciaccio, M.
- Anno di pubblicazione: 2023
- Tipologia: Lettera
- OA Link: http://hdl.handle.net/10447/621328
Abstract
Circulating histones have been suggested as critical mediators and potential diagnostic/prognostic markers in several hyperinflammatory diseases, including Sars-CoV-2 infection and classical bacterial sepsis, because their levels increase with the worsening of classical and viral sepsis