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AGATA MALTESE

The main sequelae of preterm birth: Focus on neurodevelopmental disorders

  • Autori: Maltese, Agata*; Cerroni, Francesco; Romano, Palmira; Russo, Daniela; Salerno, Margherita; Gallai, Beatrice; Marotta, Rosa; Lavano, Serenamarianna; Lavano, Francesco; Tripi, Gabriele
  • Anno di pubblicazione: 2018
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: Neonatal Intensive Care Unit; Periventricular leukomalacia; Preterm birth; Medicine (all)
  • OA Link: http://hdl.handle.net/10447/298076

Abstract

Preterm birth is a traumatic event that interrupts the physiological processes that allow the development of the Nervous System and the body systems, resulting in a multi-organ dysfunction, of an entity in inverse proportion to the gestational age, which causes respiratory, cardiovascular, metabolic, infectious endocrine problems. and neurological. In particular, at a neurological level, in the most serious cases, for macroscopic lesions of the Central Nervous System, there is the risk of incurring in evolutionary Disabilities (Infantile Cerebral Palsy etc.); but in the absence of severe damage, since the birth occurs at a critical moment of the cerebral development in which the cortex is being organized, it is possible to establish minor deficits, arising from alterations in neural connectivity.