Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome.
- Autori: Tuttolomondo, A; Pecoraro, R; Di Raimondo, D; Di Sciacca, R; Canino, B; Arnao, V; Buttà , C; Della Corte, V; Maida, C; Licata, G; Pinto, A
- Anno di pubblicazione: 2014
- Tipologia: Articolo in rivista (Articolo in rivista)
- Parole Chiave: Stroke, arterial stiffness, metabolic syndrome
- OA Link: http://hdl.handle.net/10447/90403
Abstract
Objective. The aim of our study was to evaluate the associations between arterial stiffness indexes and immune-inflammatory markers in subjects with acute ischemic stroke with and without metabolic syndrome. Materials/Methods. We enrolled 130 patients with acute ischemic stroke and metabolic syndrome, 127 patients with acute ischemic stroke without metabolic syndrome and 120 control subjects without acute stroke. Applanation tonometry was used to record the augmentation index (Aix) and pulse wave velocity (PWV). We also evaluated plasma levels of C-reactive protein (CRP), Interleukin-1beta (IL-1β), tumor necrosis factor-alpha (TNF-), Interleukin-6 (IL-6) and Interleukin-10 (IL-10), E-selectin, P-selectin, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), von Willebrand Factor (vWF) plasma levels, tissue plasminogen activator (TPA) and plasminogen activator inhibitor-1 (PAI-1). Results: In subjects with acute ischemic stroke and metabolic syndrome w...