| 2024 |
Special Issue: “Inflammatory Signaling Pathways Involved in
Gastrointestinal Diseases” |
Nota o commento |
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| 2024 |
Seseli tortuosum L. subsp. tortuosum Essential Oils and Their Principal Constituents as Anticancer Agents |
Articolo in rivista |
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| 2024 |
Synthetic Derivatives of Natural ent‐Kaurane Atractyligenin Disclose Anticancer Properties in Colon Cancer Cells, Triggering Apoptotic Cell Demise |
Articolo in rivista |
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| 2024 |
Metabolismo dei lipidi (III). Lipoproteine plasmatiche |
Capitolo o Saggio |
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| 2023 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Review essay (rassegna critica) |
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| 2023 |
Multimodal Strategies to Fight Obesity: Research on Tailored Therapies Based on Natural and Synthetic Compounds for Prevention, Management and Treatment |
Nota o commento |
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| 2023 |
Cytotoxic Effect Induced by Sicilian Oregano Essential Oil in Human Breast Cancer Cells |
Articolo in rivista |
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| 2023 |
Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory
Bowel Disease |
Review essay (rassegna critica) |
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| 2023 |
Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition |
Curatela |
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| 2023 |
Hypertrophy and ER Stress Induced by Palmitate Are Counteracted by Mango Peel and Seed Extracts in 3T3-L1 Adipocytes |
Articolo in rivista |
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| 2023 |
Seseli bocconei Guss. and S. tortuosum subsp. maritimum Guss. essential oils inhibit colon cancer cell viability |
Articolo in rivista |
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| 2023 |
Biomarkers in Laryngeal Squamous Cell Carcinoma: The Literature Review |
Articolo in rivista |
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| 2023 |
Advances in the Astonishing World of Phytochemicals State-of-the-Art for Antioxidants |
Curatela |
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| 2023 |
Phytochemical investigation and antitumor activity of coumarins from Sicilian accession of Ferulago nodosa (L.) Boiss. roots |
Articolo in rivista |
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| 2023 |
MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells |
Articolo in rivista |
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| 2023 |
Advances in the Astonishing World of Phytochemicals: State-of-the-Art for Antioxidants |
Nota o commento |
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| 2023 |
Metabolismo del tessuto adiposo• Capitolo 25 - di La Biochimica di Thomas M. Devlin |
Capitolo o Saggio |
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| 2023 |
A Deadly Liaison between Oxidative Injury and p53 Drives Methyl-Gallate-Induced Autophagy and Apoptosis in HCT116 Colon Cancer Cells |
Articolo in rivista |
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| 2022 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Abstract in atti di convegno pubblicato in rivista |
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| 2022 |
5-Azacytidine Inhibits the Activation of Senescence Program and Promotes Cytotoxic Autophagy during Trdmt1-Mediated Oxidative Stress Response in Insulinoma β-TC-6 Cells |
Articolo in rivista |
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| 2022 |
The Histone Deacetylase Inhibitor ITF2357 (Givinostat) Targets Oncogenic BRAF in Melanoma Cells and Promotes a Switch from Pro-Survival Autophagy to Apoptosis |
Articolo in rivista |
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| 2022 |
Essential oil of Foeniculum vulgare subsp. piperitum fruits exerts an anti‑tumor effect in triple‑negative breast cancer cells |
Articolo in rivista |
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| 2022 |
Bio-Waste Products of Mangifera indica L. Reduce Adipogenesis and Exert Antioxidant Effects on 3T3-L1 Cells |
Articolo in rivista |
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| 2022 |
Parthenolide and Its Soluble Analogues: Multitasking Compounds with Antitumor Properties |
Review essay (rassegna critica) |
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| 2022 |
Phytochemical-rich extracts of Helianthemum
lippii possess antimicrobial, anticancer, and antibiofilm
activities |
Articolo in rivista |
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| 2022 |
Chemical composition, cytotoxic effects, antimicrobial and antibiofilm activity of Artemisia arborescens (Vaill.) L. growing wild in the province of Agrigento, Sicily, Italy. |
Articolo in rivista |
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| 2022 |
Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity |
Nota o commento |
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| 2021 |
SICILIAN MANGO PEEL INDUCES CELLULAR STRESS ACCOMPANIED TO MITOCHONDRIAL DYSFUNCTION IN COLON CANCER CELLS |
Abstract in atti di convegno pubblicato in rivista |
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| 2021 |
Oxidative stress induced by the novel compound tributyltin(iv) ferulate promotes ER stress and autophagy in colon cancer cells |
Abstract in atti di convegno pubblicato in rivista |
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| 2021 |
Oncogenic BRAF protein as a molecular target of HDAC inhibitors in melanoma cells |
Abstract in atti di convegno pubblicato in rivista |
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| 2021 |
The good and bad of nrf2: An update in cancer and new perspectives in COVID-19 |
Articolo in rivista |
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| 2021 |
The beneficial effects of essential oils in anti-obesity treatment |
Review essay (rassegna critica) |
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| 2021 |
Redox Imbalance and Mitochondrial Release of Apoptogenic Factors at the Forefront of the Antitumor Action of Mango Peel Extract |
Articolo in rivista |
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| 2020 |
Amminoacidi e proteine |
Capitolo o Saggio |
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| 2020 |
New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action |
Articolo in rivista |
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| 2020 |
Gluten Free Diet for the Management of Non Celiac Diseases: The Two Sides of the Coin |
Articolo in rivista |
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| 2020 |
Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice |
Articolo in rivista |
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| 2020 |
P62: Friend or foe? Evidences for oncojanus and neurojanus roles |
Articolo in rivista |
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| 2020 |
Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder |
Articolo in rivista |
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| 2020 |
La chimica organica e le macromolecole biologiche |
Curatela |
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| 2020 |
ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells |
Articolo in rivista |
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| 2019 |
Novel 4-(3-phenylpropionamido), 4-(2-phenoxyacetamido) and 4-(cinnamamido) substituted benzamides bearing the pyrazole or indazole nucleus: synthesis, biological evaluation and mechanism of action |
Articolo in rivista |
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| 2019 |
Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway |
Articolo in rivista |
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| 2019 |
The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells |
Articolo in rivista |
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| 2019 |
WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner |
Articolo in rivista |
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| 2018 |
Ethanol promotes survival and tumor progression of colon cancer cells |
Contributo in atti di convegno pubblicato in volume |
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| 2018 |
Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review |
Articolo in rivista |
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| 2018 |
Sicilian litchi fruit extracts induce autophagy versus apoptosis switch in human colon cancer cells |
Articolo in rivista |
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| 2018 |
The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer |
Review essay (rassegna critica) |
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| 2018 |
Biochimica delle cellule tumorali |
Capitolo o Saggio |
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| 2017 |
Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas |
Review essay (rassegna critica) |
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| 2017 |
Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence |
Articolo in rivista |
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| 2017 |
Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways |
Review essay (rassegna critica) |
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| 2017 |
Derivati policiclici con struttura complessa dotati di attività antiproliferativa |
Abstract in atti di convegno pubblicato in volume |
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| 2017 |
Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action |
Articolo in rivista |
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| 2016 |
Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells |
Abstract in atti di convegno pubblicato in volume |
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| 2016 |
Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound |
Articolo in rivista |
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| 2016 |
Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence |
Abstract in atti di convegno pubblicato in rivista |
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| 2016 |
Isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives endowed with anti-proliferative Activity. |
Abstract in atti di convegno pubblicato in volume |
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| 2016 |
The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms |
Articolo in rivista |
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| 2016 |
The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells |
Articolo in rivista |
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| 2016 |
Synthesized benzamido derivatives exert antiproliferative effects by DNA damage and ROS generation. |
Abstract in atti di convegno pubblicato in volume |
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| 2015 |
Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality |
Articolo in rivista |
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| 2015 |
Il sostegno e il miglioramento delle coltivazioni sub-tropicali in Sicilia traggono vantaggio dallo studio e dalla promozione delle loro proprietà nutrizionali. |
Contributo in atti di convegno pubblicato in volume |
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| 2015 |
ER+-derived breast cancer stem cells reveal a high expression of the serpin protease inhibitor PI-9. |
eedings |
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| 2015 |
Possible regulatory mechanisms responsible for the high expression of serpin protease inhibitor PI-9 in ER+ -derived breast cancer stem cells. |
eedings |
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| 2015 |
The Synergistic Effect of SAHA and Parthenolide in MDA-MB231 Breast Cancer Cells |
Articolo in rivista |
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| 2015 |
Different modulatory effect of the synthetic cannabinoid WIN55,212-2 on tumor cell migration. |
eedings |
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| 2014 |
The synergistic effect exerted by the HDAC inhibitor SAHA and the sesquiterpene
lactone parthenolide on triple negative breast canc
er cells |
eedings |
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| 2014 |
Synthesis and antiproliferative activity of a natural like glucosyl polycyclic compound |
eedings |
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| 2014 |
Synergistic effect of the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide in triple negative breast cancer cells. |
eedings |
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| 2014 |
ATTIVITÀ ANTIPROLIFERATIVA DI UN DERIVATO POLICICLICO CON STRUTTURA COMPLESSA |
eedings |
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| 2014 |
Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3’,4’:2,3]azepino[4,5-f]azocine |
Articolo in rivista |
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| 2014 |
Synthesis and antirpoliferative activity of isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives |
eedings |
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| 2014 |
The HDAC inhibitor SAHA synergistically stimulates
the cytotoxic effect induced by Parthenolide in
MDA-MB231 cells |
eedings |
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| 2014 |
The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells |
Articolo in rivista |
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| 2014 |
Heat shock protein 60 (Hsp60) modulation by the Histon Deacetylase Inhibitor (HDAC-i) SAHA in mucoepidermoid tumor H292 cells |
eedings |
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| 2013 |
Parthenolide induces EGF receptor phosphorylation and superoxide anion production in MDA-MB231 breast cancer cells. |
eedings |
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| 2013 |
Synergistic cytotoxic interaction of the HDAC inhibitor SAHA with the natural compound parthenolide in MDA-MB231 breast cancer cells. |
eedings |
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| 2013 |
Il partenolide stimola la produzione di ROS e autofagia in cellule di carcinoma mammario MDA-MB231.Il suo analogo solubile DMAPT inibisce la crescita e le metastasi di xenotrapianti di tumori mammari. |
eedings |
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| 2013 |
Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells. |
Articolo in rivista |
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| 2013 |
Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells. |
Articolo in rivista |
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| 2013 |
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. |
Articolo in rivista |
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| 2012 |
SAHA/TRAIL combination induces detachment and anoikis of MDA-MB231
and MCF-7 breast cancer cells |
Articolo in rivista |
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| 2012 |
Parthenolide induces caspase-independent cell death in osteosarcoma, melanoma and breast cancer cells through the induction of oxidative stress. |
eedings |
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| 2012 |
Il partenolide induce morte in cellule di osteosarcoma umano MG63 mediante un meccanismi caspasi-indipendente, mediato da AIF. |
eedings |
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| 2012 |
Parthenolide induces caspase-independent cell death mediated by AIF in osteosarcoma and melanoma cells. |
eedings |
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| 2012 |
Parthenolide induces caspase-independent and AIF mediated cell death in tumor cells |
eedings |
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| 2012 |
Evaluation of the in vitro and in vivo antineoplastic effects of
Parthenolide on MDA-MB231 breast cancer cells |
eedings |
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| 2011 |
Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. |
Articolo in rivista |
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| 2011 |
The mechanism of parthenolide-induced cell death in tumor cell lines. |
eedings |
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| 2010 |
Anti tumor action of the natural compound parthenolide |
eedings |
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| 2009 |
Parthenolide sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis |
eedings |
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| 2009 |
Composizioni farmaceutiche per il trattamento di tumori epatici |
Brevetto |
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| 2009 |
Synergistic interaction between
Parthenolide and TRAIL induces apoptosis
in human hepatocarcinoma cells. |
eedings |
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| 2009 |
The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation |
Articolo in rivista |
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| 2008 |
The sensitization of HepG2 and HT29 cells to TRAIL-induced apoptosis by histone deacetylase inhibitors is mediated by down-regulation of AKT and NF-kB. |
eedings |
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| 2008 |
The mechanism by which histone deacetylase inhibitors sensitize hepatoma and colon cancer cells to TRAIL-induced apoptosis |
eedings |
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| 2008 |
HISTONE DEACETYLASE INHIBITORS SENSITIZE HEPATOMA CELLS TO TRAIL_INDUCED APOPTOSIS |
eedings |
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| 2008 |
Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
Articolo in rivista |
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| 2008 |
Western Blotting Analysis |
Capitolo o Saggio |
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| 2008 |
Identification of Protein Complexes by Coimmunoprecipitation |
Capitolo o Saggio |
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| 2008 |
Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review). |
Articolo in rivista |
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| 2007 |
Role of the acetylation of p53 and histones in SAHA-induced apoptosis in human hepatoma HepG2 cells. |
eedings |
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| 2007 |
Histone deacetylase inhibitors in cancer therapy: Biological and clinical implications. |
Monografia |
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| 2007 |
Histone deacetylase inhibitors: Epigenetic drugs acting by pleiotropic apoptotic mechanism in tumor cells and highly potent in combination with other antitumor agents. |
eedings |
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| 2007 |
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. |
Articolo in rivista |
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| 2007 |
Novel Apoptotic drugs in targeting tumor cells |
Curatela |
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| 2007 |
THE APOPTOTIC EFFECT INDUCED IN HepG2 CELLS BY INHIBITORS OF HISTONE DEACETYLASES IS CORRELATED WITH ACETYLATION OF p53 AND HISTONES. |
eedings |
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| 2007 |
The proteasome inhibitor bortezomib in programmed cell death and cancer therapy |
Monografia |
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| 2006 |
“Acetilazione di p53 e degli istoni nell’apoptosi indotta dal SAHA in cellule di epatoma umano HepG2” |
eedings |
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| 2006 |
“Effects of histone deacetylase inhibitors in human hepatoma cells and synergistic apoptotic interaction with the proteasome inhibitor Bortezomib” |
eedings |
Go to |
| 2006 |
SAHA induces acetylation of p53 and histones in human hepatoma HepG2 cells |
eedings |
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| 2006 |
New perspectives in tumor therapy: molecular aspects, 2006 |
Curatela |
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| 2006 |
Synergistic apoptotic effect in HepG2 cells between bortezomib and hystone deacetylase inhibitors |
eedings |
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| 2006 |
THE ROLE OF THE EXTRINSIC PATHWAY OF APOPTOSIS IN THE EFFECT INDUCED BY SAHA IN HUMAN HEPATOMA CELLS. |
eedings |
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| 2006 |
JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways |
Articolo in rivista |
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| 2005 |
SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. |
eedings |
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| 2005 |
THE APOPTOTIC EFFECT EXERTED IN HUMAN HEPATOMA CELLS BY THE INHIBITOR OF HISTONE DEACETYLASE SAHA EITHER ALONE OR IN COMBINATION WITH BORTEZOMIB. |
eedings |
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| 2005 |
JNK AND AP-1 MEDIATE APOPTOSIS INDUCED BY BORTEZOMIB IN HEPATOMA HEPG2 CELLS. |
eedings |
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| 2004 |
Sodium butyrate induces apoptosis in human hepatoma cells by a mitochondria/caspase pathway, associated with degradation of beta-catenin, pRb and Bcl-XL. |
Articolo in rivista |
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| 2004 |
Proteasome inhibitor Velcade induces apoptosis in hepatoma HepG2 cells stimulating both the extrinsic and the intrinsic apoptotic pathways. |
eedings |
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| 2004 |
The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. |
eedings |
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| 2004 |
Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL. |
Articolo in rivista |
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| 2003 |
The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells |
Articolo in rivista |
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| 2003 |
Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb |
Articolo in rivista |
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| 2002 |
Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-Xs and activation of caspase-3 |
Articolo in rivista |
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| 2001 |
Sodium phenylbutyrate induces apoptosis in human retinoblastoma Y79 cells: The effect of combined treatment with the topoisomerase I-inhibitor topotecan |
Articolo in rivista |
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| 2001 |
pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. |
Articolo in rivista |
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| 2000 |
Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells |
Articolo in rivista |
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| 2000 |
Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress |
Articolo in rivista |
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| 1999 |
The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells |
Articolo in rivista |
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| 1998 |
Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells |
Articolo in rivista |
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| 1998 |
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors |
Articolo in rivista |
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| 1998 |
Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide |
Articolo in rivista |
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| 1998 |
The apoptotic effects of cisplatin and carboplatin in retinoblastoma Y79 cells |
Articolo in rivista |
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| 1998 |
Increased cyclin E level in retinoblastoma cells during programmed cell death |
Articolo in rivista |
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| 1997 |
Insulin and IGFs induce apoptosis in chick embryo retinas deprived of L-glutamine |
Articolo in rivista |
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| 1997 |
Differentiation of Y79 cells induced by prolonged exposure to insulin |
Articolo in rivista |
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| 1996 |
Role of insulin-like growth factors in autocrine growth of human retinoblastoma Y79 cells |
Articolo in rivista |
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| 1995 |
Chick embryo retina development in vitro: the effect of insulin |
Articolo in rivista |
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| 1994 |
Insulin synthesis in chick embryo retinas during development |
Articolo in rivista |
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| 1994 |
Synthesis of insulin and its effects in Y79 human retinoblastoma cells |
Articolo in rivista |
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