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MARIANNA LAURICELLA

Curriculum and Research

Subjects

Academic Year Subject identification code Subject name ECTS Course of study
2021/2022 01542 BIOCHIMICA (MODULO) 5 OTTICA E OPTOMETRIA
2021/2022 01567 BIOCHIMICA E FISIOLOGIA C.I. 10 OTTICA E OPTOMETRIA
2021/2022 01570 BIOCHIMICA I (MODULO) 6 MEDICINA E CHIRURGIA
2021/2022 96505 BIOCHIMICA SISTEMATICA UMANA 7 MEDICINA E CHIRURGIA
2021/2022 17447 CHIMICA E BIOCHIMICA C.I. 12 MEDICINA E CHIRURGIA

Publications

Date Title Type Record
2021 SICILIAN MANGO PEEL INDUCES CELLULAR STRESS ACCOMPANIED TO MITOCHONDRIAL DYSFUNCTION IN COLON CANCER CELLS Abstract in atti di convegno pubblicato in rivista Go to
2020 Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder Articolo in rivista Go to
2020 ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells Articolo in rivista Go to
2020 Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice Articolo in rivista Go to
2020 Amminoacidi e proteine Capitolo o Saggio Go to
2020 Gluten Free Diet for the Management of Non Celiac Diseases: The Two Sides of the Coin Articolo in rivista Go to
2020 La chimica organica e le macromolecole biologiche Curatela Go to
2020 New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action Articolo in rivista Go to
2020 P62: Friend or foe? Evidences for oncojanus and neurojanus roles Articolo in rivista Go to
2019 WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner Articolo in rivista Go to
2019 Novel 4-(3-phenylpropionamido), 4-(2-phenoxyacetamido) and 4-(cinnamamido) substituted benzamides bearing the pyrazole or indazole nucleus: synthesis, biological evaluation and mechanism of action Articolo in rivista Go to
2019 The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells Articolo in rivista Go to
2019 Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway Articolo in rivista Go to
2018 Sicilian litchi fruit extracts induce autophagy versus apoptosis switch in human colon cancer cells Articolo in rivista Go to
2018 Biochimica delle cellule tumorali Capitolo o Saggio Go to
2018 Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review Articolo in rivista Go to
2018 Ethanol promotes survival and tumor progression of colon cancer cells Contributo in atti di convegno pubblicato in volume Go to
2018 The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer Review essay (rassegna critica) Go to
2017 Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas Review essay (rassegna critica) Go to
2017 Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action Articolo in rivista Go to
2017 Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways. Review essay (rassegna critica) Go to
2017 Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence Articolo in rivista Go to
2017 Derivati policiclici con struttura complessa dotati di attività antiproliferativa Abstract in atti di convegno pubblicato in volume Go to
2016 Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2016 Isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives endowed with anti-proliferative Activity. Abstract in atti di convegno pubblicato in volume Go to
2016 The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms. Articolo in rivista Go to
2016 Synthesized benzamido derivatives exert antiproliferative effects by DNA damage and ROS generation. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2016 The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells Articolo in rivista Go to
2016 Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence Abstract in atti di convegno pubblicato in rivista Go to
2016 Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound Articolo in rivista Go to
2015 Different modulatory effect of the synthetic cannabinoid WIN55,212-2 on tumor cell migration. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2015 Il sostegno e il miglioramento delle coltivazioni sub-tropicali in Sicilia traggono vantaggio dallo studio e dalla promozione delle loro proprietà nutrizionali. Contributo in atti di convegno pubblicato in volume Go to
2015 The Synergistic Effect of SAHA and Parthenolide in MDA-MB231 Breast Cancer Cells Articolo in rivista Go to
2015 Possible regulatory mechanisms responsible for the high expression of serpin protease inhibitor PI-9 in ER+ -derived breast cancer stem cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2015 Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality Articolo in rivista Go to
2015 ER+-derived breast cancer stem cells reveal a high expression of the serpin protease inhibitor PI-9. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 The synergistic effect exerted by the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide on triple negative breast canc er cells Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3’,4’:2,3]azepino[4,5-f]azocine Articolo in rivista Go to
2014 Synthesis and antirpoliferative activity of isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 The HDAC inhibitor SAHA synergistically stimulates the cytotoxic effect induced by Parthenolide in MDA-MB231 cells Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 Synergistic effect of the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide in triple negative breast cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 ATTIVITÀ ANTIPROLIFERATIVA DI UN DERIVATO POLICICLICO CON STRUTTURA COMPLESSA Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 Synthesis and antiproliferative activity of a natural like glucosyl polycyclic compound Proceedings (TIPOLOGIA NON ATTIVA) Go to
2014 The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells Articolo in rivista Go to
2014 Heat shock protein 60 (Hsp60) modulation by the Histon Deacetylase Inhibitor (HDAC-i) SAHA in mucoepidermoid tumor H292 cells Proceedings (TIPOLOGIA NON ATTIVA) Go to
2013 Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells. Articolo in rivista Go to
2013 Il partenolide stimola la produzione di ROS e autofagia in cellule di carcinoma mammario MDA-MB231.Il suo analogo solubile DMAPT inibisce la crescita e le metastasi di xenotrapianti di tumori mammari. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2013 Synergistic cytotoxic interaction of the HDAC inhibitor SAHA with the natural compound parthenolide in MDA-MB231 breast cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2013 Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. Articolo in rivista Go to
2013 Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells. Articolo in rivista Go to
2013 Parthenolide induces EGF receptor phosphorylation and superoxide anion production in MDA-MB231 breast cancer cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2012 SAHA/TRAIL combination induces detachment and anoikis of MDA-MB231 and MCF-7 breast cancer cells Articolo in rivista Go to
2012 Parthenolide induces caspase-independent cell death mediated by AIF in osteosarcoma and melanoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2012 Evaluation of the in vitro and in vivo antineoplastic effects of Parthenolide on MDA-MB231 breast cancer cells Proceedings (TIPOLOGIA NON ATTIVA) Go to
2012 Parthenolide induces caspase-independent and AIF mediated cell death in tumor cells Proceedings (TIPOLOGIA NON ATTIVA) Go to
2012 Il partenolide induce morte in cellule di osteosarcoma umano MG63 mediante un meccanismi caspasi-indipendente, mediato da AIF. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2012 Parthenolide induces caspase-independent cell death in osteosarcoma, melanoma and breast cancer cells through the induction of oxidative stress. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2011 The mechanism of parthenolide-induced cell death in tumor cell lines. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2011 Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. Articolo in rivista Go to
2010 Anti tumor action of the natural compound parthenolide Proceedings (TIPOLOGIA NON ATTIVA) Go to
2009 Synergistic interaction between Parthenolide and TRAIL induces apoptosis in human hepatocarcinoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2009 Composizioni farmaceutiche per il trattamento di tumori epatici Brevetto Go to
2009 The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation Articolo in rivista Go to
2009 Parthenolide sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis Proceedings (TIPOLOGIA NON ATTIVA) Go to
2008 Western Blotting Analysis Capitolo o Saggio Go to
2008 Identification of Protein Complexes by Coimmunoprecipitation Capitolo o Saggio Go to
2008 Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review). Articolo in rivista Go to
2008 Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. Articolo in rivista Go to
2008 The sensitization of HepG2 and HT29 cells to TRAIL-induced apoptosis by histone deacetylase inhibitors is mediated by down-regulation of AKT and NF-kB. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2008 The mechanism by which histone deacetylase inhibitors sensitize hepatoma and colon cancer cells to TRAIL-induced apoptosis Proceedings (TIPOLOGIA NON ATTIVA) Go to
2008 HISTONE DEACETYLASE INHIBITORS SENSITIZE HEPATOMA CELLS TO TRAIL_INDUCED APOPTOSIS Proceedings (TIPOLOGIA NON ATTIVA) Go to
2007 Histone deacetylase inhibitors in cancer therapy: Biological and clinical implications. Monografia Go to
2007 Role of the acetylation of p53 and histones in SAHA-induced apoptosis in human hepatoma HepG2 cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2007 THE APOPTOTIC EFFECT INDUCED IN HepG2 CELLS BY INHIBITORS OF HISTONE DEACETYLASES IS CORRELATED WITH ACETYLATION OF p53 AND HISTONES. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2007 SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. Articolo in rivista Go to
2007 Histone deacetylase inhibitors: Epigenetic drugs acting by pleiotropic apoptotic mechanism in tumor cells and highly potent in combination with other antitumor agents. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2007 The proteasome inhibitor bortezomib in programmed cell death and cancer therapy Monografia Go to
2007 Novel Apoptotic drugs in targeting tumor cells Curatela Go to
2006 New perspectives in tumor therapy: molecular aspects, 2006 Curatela Go to
2006 SAHA induces acetylation of p53 and histones in human hepatoma HepG2 cells Proceedings (TIPOLOGIA NON ATTIVA) Go to
2006 JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways Articolo in rivista Go to
2006 “Acetilazione di p53 e degli istoni nell’apoptosi indotta dal SAHA in cellule di epatoma umano HepG2” Proceedings (TIPOLOGIA NON ATTIVA) Go to
2006 Synergistic apoptotic effect in HepG2 cells between bortezomib and hystone deacetylase inhibitors Proceedings (TIPOLOGIA NON ATTIVA) Go to
2006 THE ROLE OF THE EXTRINSIC PATHWAY OF APOPTOSIS IN THE EFFECT INDUCED BY SAHA IN HUMAN HEPATOMA CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2006 “Effects of histone deacetylase inhibitors in human hepatoma cells and synergistic apoptotic interaction with the proteasome inhibitor Bortezomib” Proceedings (TIPOLOGIA NON ATTIVA) Go to
2005 SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2005 JNK AND AP-1 MEDIATE APOPTOSIS INDUCED BY BORTEZOMIB IN HEPATOMA HEPG2 CELLS. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2005 THE APOPTOTIC EFFECT EXERTED IN HUMAN HEPATOMA CELLS BY THE INHIBITOR OF HISTONE DEACETYLASE SAHA EITHER ALONE OR IN COMBINATION WITH BORTEZOMIB. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2004 The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2004 Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL. Articolo in rivista Go to
2004 Proteasome inhibitor Velcade induces apoptosis in hepatoma HepG2 cells stimulating both the extrinsic and the intrinsic apoptotic pathways. Proceedings (TIPOLOGIA NON ATTIVA) Go to
2004 Sodium butyrate induces apoptosis in human hepatoma cells by a mitochondria/caspase pathway, associated with degradation of beta-catenin, pRb and Bcl-XL. Articolo in rivista Go to
2003 The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells Articolo in rivista Go to
2003 Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb Articolo in rivista Go to
2002 Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-Xs and activation of caspase-3 Articolo in rivista Go to
2001 Sodium phenylbutyrate induces apoptosis in human retinoblastoma Y79 cells: The effect of combined treatment with the topoisomerase I-inhibitor topotecan Articolo in rivista Go to
2001 pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. Articolo in rivista Go to
2000 Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells Articolo in rivista Go to
2000 Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress Articolo in rivista Go to
1999 The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells Articolo in rivista Go to
1998 Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide Articolo in rivista Go to
1998 The apoptotic effects of cisplatin and carboplatin in retinoblastoma Y79 cells Articolo in rivista Go to
1998 Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors Articolo in rivista Go to
1998 Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells Articolo in rivista Go to
1998 Increased cyclin E level in retinoblastoma cells during programmed cell death Articolo in rivista Go to
1997 Differentiation of Y79 cells induced by prolonged exposure to insulin Articolo in rivista Go to
1997 Insulin and IGFs induce apoptosis in chick embryo retinas deprived of L-glutamine Articolo in rivista Go to
1996 Role of insulin-like growth factors in autocrine growth of human retinoblastoma Y79 cells Articolo in rivista Go to
1995 Chick embryo retina development in vitro: the effect of insulin Articolo in rivista Go to
1994 Insulin synthesis in chick embryo retinas during development Articolo in rivista Go to
1994 Synthesis of insulin and its effects in Y79 human retinoblastoma cells Articolo in rivista Go to