Head-to-Head Comparison of FDG and Radiolabeled FAPI PET: A Systematic Review of the Literature
- Autori: Guglielmo P.; Alongi P.; Baratto L.; Abenavoli E.; Buschiazzo A.; Celesti G.; Conte M.; Filice R.; Gorica J.; Jonghi-Lavarini L.; Lanzafame H.; Laudicella R.; Librando M.; Linguanti F.; Mattana F.; Miceli A.; Olivari L.; Piscopo L.; Romagnolo C.; Santo G.; Vento A.; Volpe F.; Evangelista L.
- Anno di pubblicazione: 2023
- Tipologia: Review essay (rassegna critica)
- OA Link: http://hdl.handle.net/10447/673158
Abstract
FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging, which have demonstrated several advantages over [18F]FDG, especially in the case of low-grade or well-differentiated tumors. We conducted this systematic review to evaluate all the studies where a head-to-head comparison had been performed to explore the potential utility of FAPI tracers in clinical practice. FAPI-based radiopharmaceuticals have shown promising results globally, in particular in detecting peritoneal carcinomatosis, but studies with wider populations are needed to better understand all the advantages of these new radiopharmaceuticals.