The diagnostic accuracy of increased late night salivary cortisol for Cushing's syndrome: a real-life prospective study
- Autori: Ceccato, F; Marcelli, G; Martino, M; Concettoni, C; Brugia, M; Trementino, L; Michetti, G; Arnaldi, G
- Anno di pubblicazione: 2019
- Tipologia: Articolo in rivista
- OA Link: http://hdl.handle.net/10447/650913
Abstract
A prompt diagnosis of Cushing's Syndrome (CS) in high-risk populations is mandatory: 1-mg dexamethasone suppression test (1-mg DST), late night salivary cortisol (LNSC), and urinary-free cortisol (UFC) are recommended, despite thresholds calculated in retrospective studies. Our aim was to study the diagnostic accuracy of LNSC measured with chemiluminescence assay in a prospective study, confirming discrepancies with mass spectrometry (MS).