Adult Human Stem Cells:
Signalling, Differentiation, Transplantation
Palermo , May 19-20 th 2006
Department of Experimental Medicine
Friday 19th of May 2006
3.00-3.30 p.m. : Opening Ceremony
Prof. Giovanni Zummo, President of the Organizing Committee
On. Prof. Bartolo Sammartino, President of the “Accademia Nazionale della Politica”
Prof. Giovanni Orlandini, President of the “Società Italiana di Anatomia e Istologia”
Prof. Giovanni Peri, President of the “European Association of Clinical Anatomy”
3.30-4.00 p.m. : Lecture; Chairmen: Prof. A.F. Manzoli, Prof. B. Gridelli
Prof. Giorgio Zauli, Università di Trieste
Role of TRAIL in osteoclastogenesis
4.00-5.30 p.m. : I Session; Chairmen: Prof. S. Capitani, Prof. E. Gaudio
Dr. Antonio De Luca, Seconda Università di Napoli
Regulatory factors of the cell cycle: new insights into the control of muscle differentiation.
Dr. Valentina Di Felice, Università di Palermo
Ultrastructural and functional investigation of c-kit positive cells isolated from adult rat myocardium.
Dr. Roberta Fiume, Università di Bologna
Nuclear inositol signaling in hematopoietic cells
5.30-5.50 p.m. : Coffee break
5.50-7.20 p.m. : II Session; Chairmen: Prof. M.L. Carnazza, Prof. L. Cocco
Dr. Giuliana Gobbi, Università di Parma
Role of PKCepsilon in hematopoietic differentiation
Dr. Federica Brugnoli, Università di Ferrara
Role of Vav1 in differentiation of myeloid precursors
Dr. Riccardo Mandracchia, Università di Palermo
Human umbilical cord: potency of the cellular microenvironment
7.20-7.30 p.m. : Conclusions
Saturday 20 th of May 2006
9.00- 11.00 a .m. : III Session; Chairmen: Prof. S. Miscia, Prof. M. Vitale
Dr. Fabio Triolo, University of Pittsburgh School of Medicine
Congestive Heart Failure Treatment with Autologous Stem Cell Therapy
Dr. Maria Grazia Mancino , Università di Roma “ La Sapienza ”
Update on Liver Stem Cells
Dr. Beatriz Gonzalez Galvez, Fondazione San Raffaele del Monte Tabor, Milano
Adult cardiac mesoangioblasts: isolation from mice and human explants
Dr. Fabio Bucchieri, Università di Palermo
Three-dimensional culture models: a novel approach to the study of the epithelial mesenchimal trophic unit.
11.00- 11.20 a .m. : Coffee break
11.20 a .m.-12.50 p.m. : IV Session; Chairmen: Prof. G. Anastasi, Prof. S. Zecchi
Dr. Francesco Cappello, Università di Palermo
Role of mitochondrial chaperones in cancer development
Dr. Barbara Ghinassi , Università di Chieti
Altered proliferation/differentiation potential of the common megakaryocytic-erythroid progenitors (MEP) from mice carrying the hymorphic gata1 low mutation
Dr. Anna Mauro, Università di Palermo
Regulation of neurogenesis in the adult brain
12.50-1.00 p.m. :
Conclusions
T he Chromogranin A-derived Vasostatin peptides:
from Biology to Pathology
Cefalù ( Palermo ), 22 th – 25 th October 2006
Museo Mandralisca
Sunday 22 October
Afternoon
15:00-20:00 Get together, welcome and workshop opening (Prof. G. Zummo)
Monday 23 October
I Session of Presentation
Chair: B. Tota
K.B. Helle ( Bergen , Norway )
“Vasostatins: multifunctional peptides with homeostatic potentials”
S. Mahata (San Diego, California)
“Role of catestatin in the development of hypertension”
General Discussion
I Poster Section
Lunch
II Session of Presentation
Chair: G. Alloatti
M. Metz-Boutigue (Strasbourg, France)
“Implication of Vasostatin-containing peptides in the innate immunity”
F. Mulè ( Palermo , Italy )
“Actions of Vasostatins on gastrointestinal function in rodents”
General Discussion
II Poster Section
Dinner
Tuesday 24 October
III Session of Presentations
Chair: K.B. Helle
A.Corti ( Milan , Italy )
“Chromogranin A in hypertrophic cardiomyopathy”
R. Mazza ( Cosenza , Italy )
“Comparative aspects of cardio-inhibitory action of vasostatin 1 in eel and frog hearts”
General Discussion
III Poster Section
Lunch
IV Session of Presentations
Chair: A. Corti
T. Angelone (Cosenza, Italy)
“Vasostatins as modulators of cardiac performance in the isolated perfused rat Langendorff heart”
D. Aunis ( Strasbourg , France )
“Comparative analysis of Vasostatin in serum from patients with severe sepsis and control”
General Discussion
IV Poster Section
Dinner
Wednesday 25 October
V Session of Presentation
Chair: M. Metz-Boutigue
Y. Goumon ( Strasbourg , France )
“Structural and biological characterization of secreted vasostatin-containing peptides as paracrine cardiac mediators”
G. Alloatti ( Torino , Italy )
“Effects of Vasostatins 1 on calcium current and contractility in rat ventricular myocardium”
General Discussion
V Poster Section
Lunch
VI Session of Presentation
Chair: D. Aunis
V. Di Felice (Palermo, Italy)
“Cell-extracellular matrix interaction: a putative non-conventional target of Vasostatin-1”
G. Losano ( Torino , Italy )
“Protection against ischemia/reperfusion injuries by Vasostatin 1 in the isolated rat heart”
General Discussion
VI Poster Section
Concluding Remarks
Dinner
Clinical Anatomy and Information Technology:
Proposal of Cooperation between the University of Palermo and
the Romanian Universities
Palermo, Palazzo Steri,
December 3rd—4th, 2006
3rd December 2006, Palazzo Steri, Sala Carapezza
9.30—12.30: Round table
“The role of information technology in Clinical Anatomy. Distance education and new research possibilities”.
Chairmen: G. Orlandini, M. Ifrim, G. Peri
Speakers:
Prof. Elio Adelfio Cardinale— Prof. Giovanni Orlandini— Prof. Mircea Ifrim— Prof. Florian Popa— Prof. Cristian Dragomir— Prof. Nadia Schmidt— Prof. Stefan Iosif Dragulescu— Prof. Costantin Copotoiu— Prof. Victor Ciupina— Prof. Ciurea Tudorel— Prof. Teodor Traian Maghiar— Prof. Costantin Oprean— Prof. Giovanni Zummo— Prof. Ing. Salvatore Gaglio— Prof. Ing. Antonio Gentile— Prof. Ing Roberto Pirrone— Prof. Ing. Edoardo Ardizzone— Dott. Ing. Vincenzo Cannella— Prof. Ing. Salvatore Vitabile
4th December 2006, Palazzo Steri, Sala Carapezza
10.30—13.30: Round table
“Scientific, cultural and environmental cooperation between the University of Palermo and the Romanian Universities ”.
Speakers:
On. Dott. Salvatore Cuffaro
Presidente della Regione Siciliana
On. Dott. Francesco Musotto
Presidente della Provincia Regionale di Palermo
Dott. Maurizio Gambino
Presidente del Consiglio Provinciale di Palermo
Avv. Diego Cammarata
Sindaco di Palermo
Prof. Giuseppe Silvestri— Prof. Florian Popa— Prof. Cristian Dragomir— Prof. Nadia Schmidt— Prof. Stefan Iosif Dragulescu - Prof. Costantin Copotoiu— Prof. Victor Ciupina— Prof. Ciurea Tudorel - Prof. Teodor Traian Maghiar— Prof. Costantin Oprean — Prof. Pasquale Assennato (Delegato del Rettore per le Relaz. Internazionali) - Dott. Bartolomeo Vienna (Ufficio Cooperazione della Regione Sicilia) — Prof. Giovanni Peri (Coordinatore dei Rapporti tra la Società Italiana di Anatomia e Istologia e la Società Rumena di Anatomia).
Progresses in the Knowledge of Heart Failure:
Pathogenesis, Diagnosis and Treatment
Stem Cells and 2007+ Advances
Palermo ( Italy ), 25 th – 26 th May 2007
Department of Experimental Medicine
Friday 25th May 2007
3.00 p.m. : Opening Ceremony
3.30 p.m. : I Session of Presentations
Topic: Is the Human Heart a Source of Adult Stem Cells?
Chairmen: F. Siclari (Lugano), G. Zummo (Palermo)
Speakers :
DV Miller ( Rochester , USA ) Heterologous tissue in healed myocardial infarction: a clue to stem cell activation?
A De Luca ( Napoli , Italy ) Proliferation toward differentiation in muscle cells
V Di Felice ( Palermo , Italy ) Ultrastructural and functional investigation of c-Kit positive cells isolated from adult myocardium
5.00 p.m. : General Discussion
5.30 p.m. : Coffee break
________________________________________________________________________________
6.00 p.m. : II Session of Presentations
Topic: Pathophysiology of Heart Failure
Chairmen: A. Di Stefano (Veruno), L. Marasà ( Palermo )
Speakers :
E Eleuteri ( Veruno , Italy ) Endothelial-endocardial activation and blood biomarkers in the progression of chronic heart failure
G La Rocca ( Palermo , Italy ) Oxidative stress induces myeloperoxidase expression by HUVEC and chronic heart failure endocardial endothelial cells
C Sergi ( Innsbruck , Austria ) Single nucleotide polymorphisms and myocardial dysfunction
in idiopathic dilated cardiomyopathy
7.30 p.m. : General Discussion
9:00 p.m. Conference Dinner
Saturday 26th May 2007
8.30 a.m. : III Session of Presentations
Topic: Diagnosis of Heart Failure
Chairmen: M. Midiri ( Palermo ), S. Novo ( Palermo )
Speakers :
L Natale ( Rome , Italy ) Magnetic resonance in heart failure diagnosis
S Carerj ( Messina , Italy ) Integrated non-invasive diagnosis of heart failure: Echocardiography and MRI
R Simari ( Rochester , USA ) The cardiovascular cell therapy research network- plans and progress
10.00 a.m. General Discussion
10.30 a.m. : Coffee break
________________________________________________________________________________
11.00 a.m. : IV Session of Presentations
Topic: Heart Failure Treatment
Chairman: G. Ruvolo ( Palermo ), C. Sergi ( Innsbruck )
Speakers :
R Gulati ( Rochester , USA ) Autologous endothelial cells for cardiovascular repair
M Metra ( Brescia , Italy ) Treatment of acutely decompensated chronic heart failure
S Demertzis ( Lugano , Switzerland ) Surgical options in the treatment of heart failure
12.30 p.m. : General Discussion
1.00 p.m. : Lunch
Heat shock proteins e cancro:
Dalla diagnostica molecolare agli approcci terapeutici
Dipartimento di Medicina Sperimentale , Aula "E. Nesci"
Palermo, 18-19 gennaio 2008
Venerdì 18 gennaio 2007
Dipartimento di Medicina Sperimentale, Sezione di Anatomia Umana, Aula “E. Nesci”
Introduzione al Workshop
Ore 15.00: Giovanni Zummo e Lorenzo Marasà
Morfologia e biologia molecolare: un connubio possibile?
I Sessione di Relazioni. Chairperson: Marcella Renis
Ore 15.30: Lina Matera, Università degli Studi di Torino
Il doppio ruolo delle heat shock protein 70 nella crescita tumorale.
Ore 16.00: Christian Scifo, Università degli Studi di Catania
Modificazioni nella morfologia e nell' espressione di HSPs in linee cellulari di carcinoma prostatico trattate con sostanze naturali
Ore 16.30: Barbara Tomasello, Università degli Studi di Catania
Effetto delle antocianine sulla modulazione delle proteine da stress e dello stato del DNA in cellule di carcinoma del colon .
Ore 17.00: Coffee break
II Sessione di Relazioni. Chairperson: Lina Matera
Ore 17.20: Giovanni Li Volti, Università degli Studi di Catania
Ruolo della Hsp32 nei meccanismi di proliferazione cellulare.
Ore 17.50: Giampiero La Rocca, Università degli Studi di Palermo
L'approccio proteomico nello studio delle isoforme delle Hsp: l'esempio dell'Hsp10
Ore 18.20: Francesco Cappello, Università degli Studi di Palermo
Valutazione dell'espressione dell'Hsp60 e dell'Hsp10 in tessuti umani normali e tumorali
Ore 18.50: Discussione e conclusioni
Giovanni Zummo e Lorenzo Marasà
Ore 20.30: Cena
Progressi in malattie ostruttive polmonari:
dalla patogenesi molecolare alla riabilitazione
Dipartimento di Medicina Sperimentale, Aula "E. Nesci" Via del Vespro 129 – 90127, Palermo
15 Aprile 2008
09.00 Registrazione dei partecipanti
09.30 Cerimonia d'apertura
I Session (Official language: ENGLISH )
(Chairmen: Bruno Balbi, Veruno; Mario Spatafora, Palermo )
10.00 A new 3D in vitro model for the study of asthma (Fabio Bucchieri, Palermo) 10.30 Pulmonary biomarkers in COPD: role of bronchial biopsies (Antonino Di Stefano, Veruno)
11.00 Coffee Break
11.30 The Epithelial Mesenchymal Trophic Unit in the Pathogenesis of Asthma (Donna E. Davies, Southampton) 12.00 Increment of inflammatory cells in airways of endurance athletes: what does it mean? (Maria Rosaria Bonsignore, Palermo) 12.30 Discussion
13.00 Lunch con l'esperto : discussione di casi clinici (Dr. Silvestro Ennio D'Anna, Cefalù)
II Sessione (Lingua ufficiale: ITALIANO)
(Chairmen: Maria Rosaria Bonsignore, Palermo; Giuseppe Galardi, Cefalù)
15.30 Indicazioni e linee guida della riabilitazione Respiratoria (Bruno Balbi, Veruno)
16.00 La Riabilitazione nel paziente in attesa di trapianto di polmone (Silvestro Ennio D'Anna, Cefalù)
16.30 Coffee Break
17.00 La riabilitazione nel paziente trapiantato (Patrizio Vitulo, Palermo)
17:30 La riabilitazione nel paziente neuromuscolare (Giorgio Marino, Cefalù)
18.00 Discussione e conclusione
Seconda giornata di studio su:
Stress, heat shock proteins e cancro
Ruolo delle Hsp umane e batteriche nella cancerogenesi
Palermo, 30 gennaio 2009
Sede
Aula "E. Nesci", Dipartimento di Medicina Sperimentale,
Università degli Studi di Palermo
c/o Policlinico "Paolo Giaccone", Via del Vespro 129, Palermo
Ore 15:00: Introduzione al Workshop e saluto delle Autorità
Ore 15.30: Oxidative stress and HSPs expression in tumoral cells
Moderatore: Marcella Renis, Catania
Differential expression of HO-1 in H2O2 insulted prostate carcinoma cell lines
Salvatore Grasso, Catania
Stilbenoid-induced modulation of stress and apoptosis related proteins in DU145 cells
Barbara Tomasello, Catania
Discussione
Ore 16.20: Bacterial HSPs and carcinogenesis
Moderatore: Lorenzo Marasà, Palermo
Helicobacter pylori HspB, gastric mucosa and MALT lymphoma.
Antonio De Luca, Napoli
Chlamydial Hsp60, a risk factor for oncogenesis.
Valentina Di Felice, Palermo
Discussione
Ore 17:20: Coffee break
Ore 17:40: Human HSPs and carcinogenesis
Moderatore: Giovanni Zummo, Palermo
Hsp72 controls tumor cell death via interaction with pro-apoptotic factors.
Michela Giuliano, Palermo
Hsp60 is secreted from tumor cells by various pathways.
Francesco Cappello, Palermo
Discussione
Ore 18:40: Presentazione del Microscopio Leica DMD 108
Dott. Fulvio Follari, EcosistemiService, s.n.c.
Ore 19.00: Conclusioni