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STEFANIA GRIMAUDO

Curriculum and Research

Subjects

Academic Year Subject identification code Subject name ECTS Course of study
2023/2024 85100 BIOLOGIA (MODULO) 6 MEDICINA E CHIRURGIA
2023/2024 11666 BIOLOGIA APPLICATA E GENETICA 3 INFERMIERISTICA (ABILITANTE ALLA PROFESSIONE SANITARIA DI INFERMIERE)
2023/2024 01617 BIOLOGIA E GENETICA C.I. 10 MEDICINA E CHIRURGIA
2023/2024 20323 BIOLOGY AND GENETICS 3 NURSING

Publications

Date Title Type Record
2023 Programmed cell death 1 genetic variant and liver damage in nonalcoholic fatty liver disease Articolo in rivista Go to
2023 MAFLD: a multisystem disease Recensione in rivista Go to
2023 Inflammation and autonomic balance in cirrhosis: Association between sympathetic nervous system and osteopontin, interleukin-22, interleukin-6 and interleukin-1Ra concentrations according to portal hypertension and disease severity Articolo in rivista Go to
2023 Metabolic memory in diabetic foot syndrome (DFS): MICRO-RNAS, single nucleotide polymorphisms (SNPs) frequency and their relationship with indices of endothelial function and adipo-inflammatory dysfunction Articolo in rivista Go to
2023 Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression Articolo in rivista Go to
2023 Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line Articolo in rivista Go to
2023 Metabolic memory in diabetic foot syndrome (dfs): epigenetic changes of the expression of micro-rnas and single nucleotide polymorphisms (snps) frequency in a cohort of diabetic patients with and without foot ulceration and correlation with indices of endothelial and adipo-inflammatory dysfunction Articolo in rivista Go to
2022 A cholestatic pattern predicts major liver-related outcomes in patients with non-alcoholic fatty liver disease Articolo in rivista Go to
2022 A Genetic and Metabolic Staging System for Predicting the Outcome of Nonalcoholic Fatty Liver Disease Articolo in rivista Go to
2022 Mer Tyrosine Kinase (MERTK) modulates liver fibrosis progression and hepatocellular carcinoma development Articolo in rivista Go to
2022 PSD3 downregulation confers protection against fatty liver disease Articolo in rivista Go to
2021 PNPLA3 and TLL-1 Polymorphisms as Potential Predictors of Disease Severity in Patients With COVID-19 Articolo in rivista Go to
2021 Phylogenetic analysis in the clinical risk management of an outbreak of hepatitis C virus infection among transfused thalassaemia patients in Italy Articolo in rivista Go to
2021 Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD Articolo in rivista Go to
2020 PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease Articolo in rivista Go to
2020 Neurotensin up-regulation is associated with advanced fibrosis and hepatocellular carcinoma in patients with MAFLD Articolo in rivista Go to
2020 Hepatitis C virus eradication by direct antiviral agents abates oxidative stress in patients with advanced liver fibrosis Articolo in rivista Go to
2020 SARS-CoV-2 Viral Load, IFNλ Polymorphisms and the Course of COVID-19: An Observational Study Articolo in rivista Go to
2020 Optimizing sequential systemic therapies for advanced hepatocellular carcinoma: A decision analysis Articolo in rivista Go to
2020 The "Janus" Role of C/EBPs Family Members in Cancer Progression Articolo in rivista Go to
2020 Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients with Non-alcoholic Fatty Liver Disease Articolo in rivista Go to
2020 PCSK9 rs11591147 R46L loss-of-function variant protects against liver damage in individuals with NAFLD Articolo in rivista Go to
2019 NS5A Gene Analysis by Next Generation Sequencing in HCV Nosocomial Transmission Clusters of HCV Genotype 1b Infected Patients Articolo in rivista Go to
2019 EPIGENETIC PROFILING AND THERAPEUTICS IN LIVER DISEASE Abstract in atti di convegno pubblicato in rivista Go to
2019 STAT5 and STAT5 Inhibitors in Hematological Malignancies Articolo in rivista Go to
2019 Aminopyrine breath test predicts liver-related events and death in HCV-related cirrhosis on SVR after DAA therapy Articolo in rivista Go to
2019 Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity Articolo in rivista Go to
2019 Role of myeloid-epithelial-reproductive tyrosine kinase and macrophage polarization in the progression of atherosclerotic lesions associated with nonalcoholic fatty liver disease Articolo in rivista Go to
2019 Flusso di informazione nella materia vivente Capitolo o Saggio Go to
2018 Prevalence and severity of nonalcoholic fatty liver disease by transient elastography: Genetic and metabolic risk factors in a general population Articolo in rivista Go to
2018 Hepatitis C Virus Eradication by Direct Antiviral Agents Improves Carotid Atherosclerosis in patients with Severe Liver Fibrosis Articolo in rivista Go to
2018 Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease Articolo in rivista Go to
2018 Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver Articolo in rivista Go to
2017 Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease Articolo in rivista Go to
2017 MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals Articolo in rivista Go to
2017 Effects of Pimozide Derivatives on pSTAT5 in K562 Cells Articolo in rivista Go to
2017 Fibronectin type III domain-containing protein 5 rs3480 A>G polymorphism, irisin, and liver fibrosis in patients with Nonalcoholic fatty liver disease Articolo in rivista Go to
2017 Interferon lambda 4 rs368234815 TT>δG variant is associated with liver damage in patients with nonalcoholic fatty liver disease Articolo in rivista Go to
2016 Clinical course and genetic susceptibility of primary biliary cirrhosis: Analysis of a prospective cohort Articolo in rivista Go to
2016 Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation Articolo in rivista Go to
2016 TM6SF2 rs58542926 is not associated with steatosis and fibrosis in largecohort of patients with genotype 1 chronic hepatitis C Articolo in rivista Go to
2016 SINTESI ED ATTIVITÀ ANTIPROLIFERATIVA DI NUOVI DERIVATI A STRUTTURA TETRAZEPINONICA Contributo in atti di convegno pubblicato in volume Go to
2016 Effects of Eradicating Hepatitis C Virus Infection in Patients With Cirrhosis Differ With Stage of Portal Hypertension Articolo in rivista Go to
2015 Transmembrane 6 Superfamily Member 2 Gene Variant Disentangles Nonalcoholic Steatohepatitis From Cardiovascular Disease Articolo in rivista Go to
2015 Synthesis and antiproliferative activity of 3-(2-cloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one Articolo in rivista Go to
2015 The Hepatic Expression of Vitamin D Receptor is Inversely Associated with the Severity of Liver Damage in Genotype 1 Chronic Hepatitis C Patients. Articolo in rivista Go to
2015 PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C Articolo in rivista Go to
2015 The UCP2 -866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis Articolo in rivista Go to
2015 MERTK rs4374383 polymorphism affects the severity of fibrosis in nonalcoholic fatty liver disease Articolo in rivista Go to
2015 Statin use and non-alcoholic steatohepatitis in at risk individuals Articolo in rivista Go to
2014 Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives Articolo in rivista Go to
2014 The risk of hepatocellular carcinoma in HBV cirrhosis is affected by polymorphisms of the MERTK gene Abstract in rivista Go to
2014 Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity Articolo in rivista Go to
2014 Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease Articolo in rivista Go to
2013 A natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cells Articolo in rivista Go to
2013 Role of IL-28B and inosine triphosphatase polymorphisms in efficacy and safety of Peg-Interferon and ribavirin in chronic hepatitis C compensated cirrhosis with and without oesophageal varices. Articolo in rivista Go to
2013 A rs4374383 Single Nucleotide Polymorphisms of MERTK gene is linked to a higher likelihood of hepatocellular carcinoma in patients with HCV cirrhosis Abstract in rivista Go to
2013 Effects of IL28B rs12979860 CC genotype on metabolic profile and sustained virologic response in patients with genotype 1 chronic hepatitis C Articolo in rivista Go to
2013 The new iodoacetamidobenzofuran derivative TR120 decreases STAT5 expression and induces antitumor effects in imatinib-sensitive and imatinib-resistant BCR-ABL-expressing leukemia cells. Articolo in rivista Go to
2013 In vivo liver expression of TLR2, TLR3 and TLR7 in chronic hepatitis C Articolo in rivista Go to
2013 Association of vitamin D serum levels and its common genetic determinants, with severity of liver fibrosis in genotype 1 chronic hepatitis C patients Articolo in rivista Go to
2013 PNPLA3 GG Genotype and Carotid Atherosclerosis in Patients with Non-Alcoholic Fatty Liver Disease Articolo in rivista Go to
2013 Association of vitamin D serum levels and its common genetic determinants with severity of liver fibrosis in genotype 1 chronic hepatitis C patients eedings Go to
2013 Insulin-like growth factor-I, inflammatory proteins, and fibrosis in subjects with nonalcoholic fatty liver disease Articolo in rivista Go to
2012 Risk of disease decompensation and HCC in patients with HCV cirrhosis non responders to PEG IFN plus RBV Abstract in rivista Go to
2012 Vitamin D levels and IL28B polymorphisms are related to rapid virological response to standard of care in genotype 1 chronic hepatitis C. Articolo in rivista Go to
2012 IL28B and PNPLA3 Polymorphisms Affect Histological Liver Damage in Patients with Non-alcoholic Fatty Liver Disease. Articolo in rivista Go to
2012 IL28B polymorphisms influence stage of fibrosis and spontaneous or interferon-induced viral clearance in thalassemia patients with hepatitis C virus infection. Articolo in rivista Go to
2011 High liver RBP4 protein content is associated with histological features in patients with genotype 1 chronic hepatitis C and with nonalcoholic steatohepatitis Articolo in rivista Go to
2011 3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: a novel class of potent tubulin inhibitors Articolo in rivista Go to
2011 Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[2E]-3-phenylprop-2-enoylamino}benzamides Articolo in rivista Go to
2011 Liver follicular helper T-cells in chronic hepatitis C Abstract in rivista Go to
2011 PEG-INTERFERON PLUS RIBAVIRIN IN HCV CIRRHOSIS WITH PORTAL HYPERTENSION: ROLE OF VIRAL AND HOST FACTORS IN HCV CLEARANCE Abstract in rivista Go to
2011 Synthesis of substituted 3-amino-N-phenyl-1H-indazole-1-carboxamides endowed with antiproliferative activity Articolo in rivista Go to
2011 Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives. Articolo in rivista Go to
2011 Genetic predisposition to thrombophilia in inflammatory bowel disease Articolo in rivista Go to
2010 SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 3-AMINO-N-PHENYL-1H-INDAZOLE-1-CARBOXAMIDES eedings Go to
2010 Substituted 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors Articolo in rivista Go to
2009 Superficial venous thrombosis: role of inherited deficiency of natural anticoagulants in extension to deep veins Articolo in rivista Go to
2009 Design, synthesis and structure-activity relationship of 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization. Articolo in rivista Go to
2009 Identification of biphenyl-based hybrid molecules able to decrease the intracellular level of Bcl-2 protein in Bcl-2 overexpressing leukemia cells. Articolo in rivista Go to
2009 Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides Articolo in rivista Go to
2008 Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization Articolo in rivista Go to
2008 Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells Articolo in rivista Go to
2008 Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives as antimitotic agents and inhibitors of tubulin polymerization Articolo in rivista Go to
2008 Novel Terphenyls and 3,5-Diaryl Isoxazole Derivatives Endowed with Growth Supporting and Antiapoptotic Properties Articolo in rivista Go to
2008 Superficial venous thrombosis: Prevalence of common genetic risk factors and their role on spreading to deep veins Articolo in rivista Go to
2008 Synthesis and Biological Evaluation of 1-Methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a New Class of Antimitotic Agents and Tubulin Inhibitors Articolo in rivista Go to
2008 Design, synthesis, and biological evaluation of thiophene analogues of chalcones Articolo in rivista Go to
2008 Antiproliferative Agents That Interfere with the Cell Cycle at the G(1)-->S Transition: Further Development and Characterization of a Small Library of Stilbene-Derived Compounds Articolo in rivista Go to
2007 Effetti antileucemici di due stilbeni identificati in uve provenienti da vigneti affetti da peronospora e Botrytis cinerea Articolo in rivista Go to
2007 Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization. Articolo in rivista Go to
2007 Synthesis and anticancer activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide and 1-(1H)indazol-3-yl-3-phenylureido derivatives eedings Go to
2006 Effects of Propolis in cancer cells eedings Go to
2006 Induction of differentiation by phenols crude extract of extavirgin olive oil on tumor cell lines sensitive and resistant to anticancer drugs eedings Go to
2006 Stilbene-based anticancer agents: Resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism. Articolo in rivista Go to
2006 Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors. Articolo in rivista Go to
2006 Induction of differentiation by phenols crude extract of extravirgin olive oil on tumor cell lines sensitive and resistatnt to antitumor agents eedings Go to
2006 Effects of phenols of extra virgin olive oil on HL60 cell lines sensitive and reristant to anthracyclines eedings Go to
2006 Methylenetetrahydrofolate reductase mutation in subjects with abdominal aortic aneurysm subdivided for age. Articolo in rivista Go to
2006 Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells. Articolo in rivista Go to
2006 Effects of phenols of extra vergin olive oil on Hl60 cell lines sensitive and resistant to anthracycline eedings Go to
2005 Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells Articolo in rivista Go to
2005 “Effects of combretastatin analogues on leukemic cell lines and normal hemopoietic cells” eedings Go to
2005 Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter Articolo in rivista Go to
2005 Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells Articolo in rivista Go to
2005 GENOTYPIC AND PHENOTIPIC FACTORS IN ISCHEMIC STROKE IN YOUNG ADULTS eedings Go to
2005 Heterocyclic and Phenyl Double-Bond-Locked Combretastatin Analogues Possessing Potent Apoptosis-inducing activity in HL60 and in MDR Cell lines Articolo in rivista Go to
2005 Prolonged prothrombin time, Factor VII and activated FVII levels in chronic liver disease are partly dependent on Factor VII gene polymorphisms Articolo in rivista Go to
2005 Home therapy for deep vein thrombosis and pulmonary embolism in cancer patients Articolo in rivista Go to
2004 Thrombophilia in women with unexplained fetal loss eedings Go to
2004 Resistance to gemcitabine in a lymphoma cell line resistant to Fas-mediated apoptosis Articolo in rivista Go to
2004 MTHFR allele677T band risk of abdominal aortic aneurysm eedings Go to
2004 MTHFR allele 677T and risk of abdominal aortic aneurysm eedings Go to
2002 Trombosi portale mesenterica idiopatica in paziente con doppia mutazione eterozigote del gene C677T e del gene A1298C della MTHFR Abstract in rivista Go to