Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis
- Authors: Colucci, R.; Fornai, M.; Antonioli, L.; Segnani, C.; Ippolito, C.; Pellegrini, C.; Nericcio, A.; Zizzo, M.G.; Serio, R.; Blandizzi, C.; Bernardini, N.
- Publication year: 2022
- Type: Articolo in rivista
- Key words: Cyclooxygenase; SMAD; TGF-β; fibrosis; inflammatory bowel disease
- OA Link: http://hdl.handle.net/10447/576428
Abstract
Gut fibrosis occurs under chronic inflammation. This study examined the effects of different cyclooxygenase (COX) inhibitors on fibrosis in the inflamed colon.