Familial occurrence of warthin tumour: Our experience and review of the literature

Abstract

The tumour of Warthin (WT) is the second parotid tumour for frequency after the pleomorphic adenoma, it represents about 2% to 15% of all parotid tumors. The pathogenesis of familial Warthin Tumour is unknown, even if cytogenetic abnormalities have been identified in Warthin Tumour. Among the inducing factors there is the smoke which has an important role. Familial occurrence of Warthin Tumour is rare, only five reports in the literature. Two of them were reported in brothers, two in a mother and son and one in monozygotic twins. We quote a case of familiar Warthin Tumour arisen in two brothers and we present a review of the Literature.