Repetitive TMS temporarily alters brain diffusion
- Authors: Mottaghy F.M.; Gangitano M.; Horkan C.; Chen Y.; Pascual-Leone A.; Schlaug G.
- Publication year: 2003
- Type: Articolo in rivista
- OA Link: http://hdl.handle.net/10447/436981
Abstract
The authors investigated whether repetitive transcranial magnetic stimulation (rTMS) at 1 Hz (12 minutes; 90% of motor threshold) to the primary motor cortex (M1) leads to changes in diffusion-weighted imaging (DWI). After the rTMS train, there was a temporary small restriction in diffusion within the targeted left M1 that disappeared after 5 minutes. These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects.