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SIMONA FONTANA

Isolation and characterization of Citrus limon L. derived nanovesicles: potential use as antineoplastic agent

  • Authors: Raimondo, S.; Naselli, F.; Fontana, S.; Monteleone, F.; Lo Dico, A.; Saieva, L.; Zito, G.; FLUGY PAPE', A.; Manno, M.; DI BELLA, M.; DE LEO, G.; Alessandro, R.
  • Publication year: 2015
  • Type: Proceedings (TIPOLOGIA NON ATTIVA)
  • Key words: nanovesicles, citrus limon
  • OA Link: http://hdl.handle.net/10447/132213

Abstract

We isolated and characterized nanovesicles from edible Citrus limon with size and composition similar to mammalian-derived exosomes. Furthermore we show an in vitro and in vivo anti-proliferative and pro-apoptotic effect of these vesicles. This study opens to the possibility of using this natural plant-derived nanovesicles as antineoplastic agents.