Skip to main content
Passa alla visualizzazione normale.

ROBERTO SCAFFARO

Flexible mats as promising antimicrobial systems via integration of Thymus capitatus (L.) essential oil into PLA

  • Authors: Roberto Scaffaro, Andrea Maio, Manuela D’Arrigo, Francesco Lopresti, Andreana Marino, Maurizio Bruno, Antonia Nostro
  • Publication year: 2020
  • Type: Articolo in rivista
  • OA Link: http://hdl.handle.net/10447/476637

Abstract

To develop electrospun mats loaded with Thymus capitatus (L.) essential oil (ThymEO) and to study their morpho-mechanical and antimicrobial properties. Materials & methods: Poly(lactic acid) (PLA) mats containing ThymEO were prepared by electrospinning. The effect of ThymEO on the morpho-mechanical properties of fibers was assayed by scanning electron microscopy and dynamometer measurements. The antimicrobial activity of ThymEO delivered either in liquid or vapor phase was assessed through killing curves and invert Petri dishes method. The cytotoxicity was also investigated. Results: The mechanical properties were enhanced by integrating ThymEO into PLA. Both liquid and vapors of ThymEO released from mats caused reductions of microbial viable cells. Negligible cytotoxicity was demonstrated. Conclusion: PLA/ThymEO delivery systems could be suitable for treating microbial infections.