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CLAUDIA PELLERITO

Lipid and fatty acids variations in Ciona intestinalis ovary after tri-n-butyltin(IV)chloride exposure

  • Authors: E. Puccia, C.M. Messina, M.V. Cangialosi, P. D'Agati, C. Mansueto, C. Pellerito, L. Nagy, V. Mansueto, M. Scopelliti, T. Fiore, L. Pellerito
  • Publication year: 2005
  • Type: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/33410

Abstract

Reduction of total lipids (TL) content and significant variations of triglyceride (TG) and phospholipid (PL) fractions were observed as a consequence of exposure of Ciona intestinalis ovaries to tributyltin chloride (TBTCL) solutions. In particular, an evident TG decrease and a PL increase were observed, which probably provoked an increment in membrane fluidity, because of the high concentration of long chain fatty acids and, as a consequence, PL. This could be a cell adaptive standing mechanism towards the pollutants, as observed in Saccharomyces cerevisiae. Also the increase in the content of the polyunsaturated fatty acids (PUFA), important in the synthesis of compounds such as prostaglandine which are present in the ovary in a stress situation, was probably a consequence of a defense mechanism to the stress provoked by the presence of TBTCI