Mechanisms of Ca2+ liberation at fertilization
- Authors: GERACI F; GIUDICE G
- Publication year: 2005
- Type: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/22085
Abstract
The mechanisms underlying the Ca2+ release at fertilization of several animal organisms are reported. Four main classical theories are described, i.e., that of Ca2+ release following simple sperm contact and a G protein stimulation; that of simple sperm contact followed by a tyrosine kinase receptor activation; that of the necessity of introduction by sperm into the egg of molecules for Ca2+ release; and that the molecule introduced into the marine eggs for Ca2+ release is the same Ca2+. Two other mechanisms for Ca2+ release are also illustrated: that of ryanodine receptor stimulation and that of NAADP formation.