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ITALIA DI LIEGRO

A Low Repeat Length in Oligodendrocyte Chromatin

  • Authors: Di Liegro, I.; Salemi, G.; Cestelli, A.
  • Publication year: 1985
  • Type: Articolo in rivista (Articolo in rivista)
  • Key words: Chromatin; Nucleosomal repeat length; Oligodendrocyte differentiation; Biochemistry; Cellular and Molecular Neuroscience
  • OA Link: http://hdl.handle.net/10447/216012

Abstract

Abstract: The behavior of oligodendrocyte chromatin after micrococcal nuclease digestion of nuclei was assayed in brains of rats of four different ages. During oligodendrocyte differentiation, a decreasing sensitivity of the chromatin to enzymatic attack was observed. On the other hand, the nucleosomal repeat length showed a slight tendency to increase during development. It is worth noting that even the highest values reported here for “oligodendrocyte’ chromatin repeat lengths are significantly lower than 200 base pairs, the value previously reported by others for “non‐astrocytic glia.” Copyright © 1985, Wiley Blackwell. All rights reserved