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Sepsis in head and neck cancer patients treated with chemotherapy and radiation: Literature review and consensus

  • Authors: Mirabile, A.; Numico, G.; Russi, E.; Bossi, P.; Crippa, F.; Bacigalupo, A.; De Sanctis, V.; Musso, S.; Merlotti, A.; Ghi, M.; Merlano, M.; Licitra, L.; Moretto, F.; Denaro, N.; Caspiani, O.; Buglione, M.; Pergolizzi, S.; Cascio, A.; Bernier, J.; Raber-durlacher, J.; Vermorken, J.; Murphy, B.; Ranieri, M.; Dellinger, R.
  • Publication year: 2015
  • Type: Articolo in rivista (Articolo in rivista)
  • Key words: Chemotherapy; Head and neck cancer; Radiotherapy; Sepsis; Humans; Italy; Head and Neck Neoplasms; Sepsis; Hematology; Oncology; Geriatrics and Gerontology
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The reporting of infection/sepsis in chemo/radiation-treated head and neck cancer patients is sparse and the problem is underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met with the aim of reaching a consensus on a clinical definition and management of infections and sepsis. The Delphi appropriateness method was used for this consensus. External expert reviewers then evaluated the conclusions carefully according to their area of expertise. The paper contains seven clusters of statements about the clinical definition and management of infections and sepsis in head and neck cancer patients, which had a consensus. Furthermore, it offers a review of recent literature in these topics.