Bone marrow B lymphocytes in multiple myeloma and MGUS: Focus on distribution of naïve cells and memory subsets
- Authors: Pojero, F.; Casuccio, A.; Giambanco, C.; Bulati, M.; Buffa, S.; Di Bassiano, F.; Gervasi, F.; Caruso, C.; Colonna Romano, G.
- Publication year: 2016
- Type: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/191302
Abstract
Multiple myeloma (MM) is caused by proliferation of clonal plasma cells (cPCs) in bone marrow (BM), associated with numerical and functional defects in immune subsets. An impairment of B cell compartment is involved in onset/progression of the disease.