Breakthrough in the alfa-perchlorination of acyl chlorides
- Authors: Bellesia, F; D'Anna, F; Felluga, F; Frenna, V; Ghelfi, F; Parsons, AF; Reverberi, F; Spinelli, D
- Publication year: 2012
- Type: Articolo in rivista (Articolo in rivista)
- Key words: acyl chlorides, halogenation, chlorine, base catalysis
- OA Link: http://hdl.handle.net/10447/62417
Abstract
The preparation of -perchloroacyl chlorides, from reaction of the corresponding unfunctionalized acyl halides with chlorine, was efficiently achieved under base-catalysis, using a tetraalkylammonium chloride as catalyst. The process is solvent-free and the procedure is easy, inexpensive, and suitable for scale-up.