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VALERIO MARIA BARTOLO BRUCATO

Biological evaluation of PLLA membranes, with different pore diameters, to stimulate cell adhesion and growth in vitro

  • Authors: Montesanto, S.; Fucarino, A.; Bucchieri, F.; La Carrubba, V.; Brucato, V.
  • Publication year: 2015
  • Type: Capitolo o Saggio (Capitolo o saggio)
  • Key words: Cell Adhesion; Phase separation; PLLA; polymeric Membrane; Physics and Astronomy (all)
  • OA Link: http://hdl.handle.net/10447/202193

Abstract

Polymeric membranes prepared via DIPS (Diffusion Induced Phase Separation) are widely studied and utilized as scaffolds for the regeneration of tissue. In this work, poly (L)-lactide membrane are prepared through a DIPS protocol starting from a ternary solution made of polymer, dioxane (solvent) and water (non-solvent). A three-dimensional, porous and mechanically stable membrane is desirable for ingrowth of human bronchial epithelial cells.