MONITORING OF ATYPICAL ANTIPSYCHOTIC DRUGS SUPPLIED BY THE PHARMACY OF FRATELLI PARLAPIANO HOSPITAL, RIBERA (AG), ITALY

Abstract

Mental disorders are among the worst and widespread health problems, they are associated with important repercussions on the psychosocial sphere and to high economic costs. Antipsychotic drugs used in treatments of these pathologies belong to different chemical classes, but associated to biochemical effects, pharmacological, and in part super imposable. A retrospective survey has been led on external patients, they were under antipsychotic drug treatments already in the archive and arrived to the attention of the Pharmacy of the F.lli Parlapiano Hospital, Ribera (AG), Italy in 2013. For each patient have been extrapolated: gender, date of birth, place of residence, ICD-9CM, pharmacological therapy, and prescribing centre. Collected data have been calculated through Microsoft Office Excel to notice: prevalent diagnosis; prescribed drugs; prevalence by age group; gender, and off label prescribing in patients suffering from dementia. This survey is composed of 535 patients: 463 suffering from mental disorders and 72 suffering from degenerative diseases of SNC (especially Alzheimer). The distribution of psychic and neurological disorders in the two genders is balanced and the average age is 61.55. 64.7% live in the province of Agrigento and are treated at CSM of Ribera. 434 patients suffer from non organic psychosis; 14 patients suffer from organic psychosis; 70 patients suffer from a moderate form of Alzheimer, 2 suffer from other forms of dementia, while for 25 patients no diagnosis has been noticed as the medical prescription had been done by prescription SSN. Prescribed drugs have shown the following percentages: olanzapine 33.04%; quetiapine 33.19%, risperidone 17.97%; aripiprazole 7.4%; clozapine 4.02%; asenapine 1.69%; paliperidone 1.27%, ziprasidone 0.42%. It is a common opinion in the international scientific literature that a wise use of antipsychotic drugs of second generation gives important