In vitro cellular co-colture method to induce immunological tolerance
- Autori: Giordano, C.; Coppola, A.; Pizzolanti, G.; Tomasello, L.
- Anno di pubblicazione: 2017
- Tipologia: Brevetto
- OA Link: http://hdl.handle.net/10447/301505
An in vitro method able to modulate peripheral blood mononuclear cells of patients with auto-immune organ-specific diseases is described. The protocol makes auto-reactive lymphocytes tolerogenic through a process of re-education in recognition of self-antigen after co-culture with heterologous and/or autologous fibroblast limbal stem cells.