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Monte Carlo analysis of polymer translocation with deterministic and noisy electric fields

  • Autori: Valenti , D; Denaro, G; Persano Adorno, D; Pizzolato, N; Zammito, S; Spagnolo, B
  • Anno di pubblicazione: 2012
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: polymer molecules; transport dynamics of biomolecules; noise in biological systems; Monte Carlo simulations
  • OA Link:


Polymer translocation through the nanochannel is studied by means of a Monte Carlo approach, in the presence of a static or oscillating external electric voltage. The polymer is described as a chain molecule according to the two-dimensional "bond fluctuation model". It moves through a piecewise linear channel, which mimics a nanopore in a biological membrane. The monomers of the chain interact with the walls of the channel, modelled as a reflecting barrier. We analyze the polymer dynamics, concentrating on the translocation time through the channel, when an external electric field is applied. By introducing a source of coloured noise, we analyze the effect of correlated random fluctuations on the polymer translocation dynamics.