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Noise driven translocation of short polymers in crowded solutions

  • Autori: Pizzolato, N; Fiasconaro, A; Spagnolo, B
  • Anno di pubblicazione: 2009
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: dynamics (theory), mechanical properties (DNA, RNA, membranes, bio-polymers) (theory), Brownian Motion
  • OA Link:


In this work we study the noise induced effects on the dynamics of short polymers crossing a potential barrier, in the presence of a metastable state. An improved version of the Rouse model for a flexible polymer has been adopted to mimic the molecular dynamics by both taking into account the interactions between adjacent monomers and introducing a Lennard-Jones potential between all beads. A bending recoil torque has also been included in our model. The polymer dynamics is simulated in a two-dimensional domain by numerically solving the Langevin equations of motion with a Gaussian uncorrelated noise. We find a non-monotonic behavior of the mean first-passage time and the most probable translocation time of the polymer center of inertia as a function of the polymer length at low noise intensity. We show how thermal fluctuations influence the motion of short polymers, by inducing two different regimes of translocation in the molecule transport dynamics. In this context, the role played by the length of the molecule in the translocation time is investigated.