Salta al contenuto principale
Passa alla visualizzazione normale.

GIOVANNA PITARRESI

HYDROGELS OF HYALURONIC ACID AND alpha, beta-POLYASPARTYLHYDRAZIDE AND THEIR BIOMEDICAL AND PHARMACEUTICAL USES

  • Autori: Giammona, G.; Pitarresi, G.; Palumbo, F.
  • Anno di pubblicazione: 2005
  • Tipologia: Brevetto

Abstract

Compositions and products based on the chemical crosslinking of hyaluronic acid with a polyfunctional polymer having a protein-like structure, bearing hydrazido pendent groups along the polymeric chain. The polymer is preferably, alpha-beta-polyaspartylhydrazide, a biocompatible macromolecule. The materials obtained after crosslinking, specifically hydrogels, undergo a reduced chemical and enzymatic degradation, unlike the starting hyaluronic acid, and they can be used to prepare systems for applications in the biomedical and pharmaceutical field.