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FABIO SALVATORE PALUMBO

Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry

  • Autori: Palumbo, FS, Pitarresi, G, Giammona, G
  • Anno di pubblicazione: 2016
  • Tipologia: Abstract in atti di convegno pubblicato in volume
  • OA Link: http://hdl.handle.net/10447/207179

Abstract

Conclusion: HA-g-PDLLA hydrogel is suitable to coat a prosthesis remaining adherent to it and distributing itself in the bone cavity. The hydrogel has been proven effective in a rabbit model of highly contaminated implant. In vivo studies have demonstrated how the intraoperative coating of implants with DAC is safe and feasible. HA-EDA-MA hydrogel is able to protect PEP from alteration during storage and it seems a good candidate for a potential once-daily oral formulation in the treatment of celiac disease.